الجمعة، 25 يوليو 2014

ScienceDaily: Top News

ScienceDaily: Top News


Earlier Stone Age artifacts found in Northern Cape of South Africa

Posted: 24 Jul 2014 02:21 PM PDT

Excavations at an archaeological site at Kathu in the Northern Cape province of South Africa have produced tens of thousands of Earlier Stone Age artifacts, including hand axes and other tools.

Parched West is using up underground water: Study points to grave implications for Western U.S. water supply

Posted: 24 Jul 2014 02:21 PM PDT

A new study finds more than 75 percent of the water loss in the drought-stricken Colorado River Basin since late 2004 came from underground resources. The extent of groundwater loss may pose a greater threat to the water supply of the western United States than previously thought.

Biologist warn of early stages of Earth's 6th mass extinction event

Posted: 24 Jul 2014 02:19 PM PDT

The planet's current biodiversity, the product of 3.5 billion years of evolutionary trial and error, is the highest in the history of life. But it may be reaching a tipping point. Scientists caution that the loss and decline of animals is contributing to what appears to be the early days of the planet's sixth mass biological extinction event. Since 1500, more than 320 terrestrial vertebrates have become extinct. Populations of the remaining species show a 25 percent average decline in abundance. The situation is similarly dire for invertebrate animal life.

How to power California with wind, water and sun

Posted: 24 Jul 2014 11:43 AM PDT

New research outlines the path to a possible future for California in which renewable energy creates a healthier environment, generates jobs and stabilizes energy prices.

Pesticide linked to three generations of disease: Methoxychlor causes epigenetic changes

Posted: 24 Jul 2014 11:42 AM PDT

Researchers say ancestral exposures to the pesticide methoxychlor may lead to adult onset kidney disease, ovarian disease and obesity in future generations.

Linking microbial, immune environment in semen to HIV viral load, transmission

Posted: 24 Jul 2014 11:42 AM PDT

HIV infection re-shapes the relationship between semen bacteria and immune factors which in turn affects viral load, suggesting that the semen microbiome plays a role in sexual transmission of HIV, researchers report. While HIV is found in many body fluids, sexual transmission through semen is the most common route of infection.

No returning to Eden: Researchers explore how to restore species in a changing world

Posted: 24 Jul 2014 11:42 AM PDT

Reversing the increasing rate of global biodiversity losses may not be possible without embracing intensive, and sometimes controversial, forms of threatened species management, according to zoologists.

Synchronization of North Atlantic, North Pacific preceded abrupt warming, end of ice age

Posted: 24 Jul 2014 11:16 AM PDT

Scientists have long been concerned that global warming may push Earth's climate system across a 'tipping point,' where rapid melting of ice and further warming may become irreversible -- a hotly debated scenario with an unclear picture of what this point of no return may look like. A new study suggests that combined warming of the North Atlantic and Pacific Oceans thousands of years ago may have provided the tipping point for abrupt warming and rapid melting of the northern ice sheets.

DNA mostly 'junk?' Only 8.2 percent of human DNA is 'functional', study finds

Posted: 24 Jul 2014 11:16 AM PDT

Only 8.2 percent of human DNA is likely to be doing something important -- is 'functional' -- say researchers. This figure is very different from one given in 2012, when some scientists involved in the ENCODE (Encyclopedia of DNA Elements) project stated that 80% of our genome has some biochemical function.

Atomic structure of key muscle component revealed

Posted: 24 Jul 2014 11:16 AM PDT

Adding to the growing fundamental understanding of the machinery of muscle cells, a group of biophysicists describe -- in minute detail -- how actin filaments are stabilized at one of their ends to form a basic muscle structure called the sarcomere. With the help of many other proteins, actin molecules polymerize to form filaments that give rise to structures of many different shapes. The actin filaments have a polarity, with a plus and minus end, reflecting their natural tendency to gain or lose subunits when not stabilized.

Leaf-mining insects destroyed with the dinosaurs, others quickly appeared

Posted: 24 Jul 2014 11:16 AM PDT

After the asteroid impact at the end of the Cretaceous period that triggered the dinosaurs' extinction and ushered in the Paleocene, leaf-mining insects in the western United States completely disappeared. Only a million years later, at Mexican Hat, in southeastern Montana, fossil leaves show diverse leaf-mining traces from new insects that were not present during the Cretaceous, according to paleontologists.

Protein couple controls flow of information into brain's memory center

Posted: 24 Jul 2014 10:40 AM PDT

Neuroscientists have succeeded in providing new insights into how the brain works by analyzing tissue samples from mice to identify how two specific proteins, 'CKAMP44' and 'TARP Gamma-8', act upon the brain's memory center. Brain function depends on the active communication between nerve cells, known as neurons. For this purpose, neurons are woven together into a dense network where they constantly relay signals to one another.

Artificial intelligence identifies the musical progression of the Beatles

Posted: 24 Jul 2014 10:40 AM PDT

Computer scientists have developed an artificial intelligence algorithm that can analyze and compare musical styles, which they have used to study the musical progression of the Beatles.

New perspective on agricultural plastic, debris burning, and air quality

Posted: 24 Jul 2014 09:45 AM PDT

To reduce fire hazard, wildland managers often utilize the silvicultural practice of mechanically cutting woody shrubs and suppressed trees. These cuttings and other post-logging debris are then burned during periods of low fire danger in order to dispose of the material. Managers often cover all or part of the debris pile with low-density polyethylene plastic, commonly referred to as agricultural plastic, in order to keep water out. Inclusion of agricultural plastic in debris piles has no effect on smoke emissions, a new study indicates.

Joblessness could kill you, but recessions could be good for your health

Posted: 24 Jul 2014 09:45 AM PDT

While previous studies of individuals have shown that employees who lose their jobs have a higher mortality rate, more comprehensive studies have shown, unexpectedly, that population mortality actually declines as unemployment rates increase. Researchers set out to better understand these seemingly contradictory findings.

Fukushima accident underscores need for U.S. to seek out new information about nuclear plant hazards

Posted: 24 Jul 2014 09:44 AM PDT

A new congressionally mandated report concludes that the overarching lesson learned from the 2011 Fukushima Daiichi nuclear accident is that nuclear plant licensees and their regulators must actively seek out and act on new information about hazards with the potential to affect the safety of nuclear plants.

Corn and soy insecticides similar to nicotine found widespread in midwest U.S. rivers

Posted: 24 Jul 2014 09:44 AM PDT

Insecticides similar to nicotine, known as neonicotinoids, were found commonly in streams throughout the Midwest, according to a new study. This is the first broad-scale investigation of neonicotinoid insecticides in the Midwestern United States and one of the first conducted within the United States.

A reward is valued more if you choose it yourself: New quirky byproduct of learning from reward

Posted: 24 Jul 2014 09:44 AM PDT

Many people value rewards they choose themselves more than rewards they merely receive, even when the rewards are actually equivalent. A new study provides evidence that this long-observed quirk of behavior is a byproduct of how the brain reinforces learning from reward.

Cancer: Treatment that prevents tumor metastasis identified in animal study

Posted: 24 Jul 2014 09:42 AM PDT

Metastasis, the strategy adopted by tumor cells to transform into an aggressive form of cancer, are often associated with a gloomy prognosis. Managing to block the metastasis or, even better, prevent their formation would be a giant step towards the fight against cancer. Researchers successfully performed this on models of human tumors in mice.

Metastatic brain tumor treatment could be on the horizon with use of SapC-DOPS

Posted: 24 Jul 2014 08:25 AM PDT

A new study has provided hope that previously studied SapC-DOPS could be used for treatment of brain cancer that has spread. "These results support the potential of SapC-DOPS for the diagnosis and therapy of primary and metastatic brain tumors which is critically needed to increase survival rates of patients with this illness," one researcher said.

Key molecule in flies identified that adjusts energy use under starvation conditions

Posted: 24 Jul 2014 08:25 AM PDT

In the fly Drosophila melanogaster, p53 is activated in certain cells to adapt the metabolic response to nutrient deprivation, thus having a global effect on the organism, researchers show. The researchers also reveal the molecular mechanisms through which the activity of p53 is regulated. The results obtained in Drosophila are useful to address the study of the molecular mechanisms of p53 in vertebrate models and to examine whether this protein is involved in diabetes and obesity.

Annual financial cost of COPD $36 billion in U.S.: CDC report

Posted: 24 Jul 2014 08:25 AM PDT

A new report outlines the total and state-specific medical and absenteeism costs of chronic obstructive pulmonary disease among adults in the United States, and lays out some projections to 2020. Chronic lower respiratory diseases, including COPD, are the third-leading cause of death in the United States. Close to 24 million US adults have evidence of impaired lung function, indicating an underdiagnosis of COPD. Smoking is a primary risk factor of COPD, and approximately 80% of COPD deaths can be attributed to smoking.

Nearly 50 years of lemur, other primates data now available online

Posted: 24 Jul 2014 07:42 AM PDT

A 48-year archive of life history data for the world's largest and most diverse collection of endangered primates is now digital and available online. The database allows visitors to view and download data for more than 3600 animals representing 27 species of lemurs, lorises and galagos -- distant primate cousins who predate monkeys and apes -- with more data to be uploaded in the future.

Mechanism that clears excess of protein linked with Type 2 diabetes

Posted: 24 Jul 2014 07:42 AM PDT

In people who do not have Type 2 diabetes, autophagy prevents the accumulation of toxic forms of IAPP, researchers have found. In people with Type 2 diabetes, the process appears to not work properly, contributing to the destruction of beta cells. As the body's insulin producers, beta cells play a key role in maintaining healthy blood sugar levels.

Cost-effective, solvothermal synthesis of heteroatom (S or N)-doped graphene developed

Posted: 24 Jul 2014 07:42 AM PDT

A research team has developed cost-effective technology to synthesize sulfur-doped and nitrogen-doped graphenes which can be applied as high performance electrodes for secondary batteries and fuel cells.

Natural products from plants protect skin during cancer radiotherapy

Posted: 24 Jul 2014 07:42 AM PDT

Plant-derived natural product chemicals could offer protection to the skin from the harmful effects of gamma radiation during cancer radiotherapy, suggests research.

New mass map of distant galaxy cluster is most precise yet

Posted: 24 Jul 2014 07:42 AM PDT

Astronomers have mapped the mass within a galaxy cluster more precisely than ever before. Created using observations from Hubble's Frontier Fields observing program, the map shows the amount and distribution of mass within MCS J0416.1-2403, a massive galaxy cluster found to be 160 trillion times the mass of the Sun.

Background TV can be bad for kids

Posted: 24 Jul 2014 07:41 AM PDT

Leaving the television on can be detrimental to children's learning and development, according to a new study. Researchers found that background television can divert a child's attention from play and learning. Regardless of family demographics, parenting can act as a buffer against the impacts of background TV, the research team found.

Dream come true for chemists? Creating organic zeolites

Posted: 24 Jul 2014 07:41 AM PDT

Traditionally, zeolites have been derived from inorganic material like silicon or aluminum. For the past several years, one research team has focused on combining zeolites with organic polymers whose main component is carbon, oxygen, hydrogen or nitrogen. A new technique and the new materials it produces can be immediately useful in catalysis and separations for chemicals production and hydrocarbon conversion for energy applications.

Discovery is key to metal wear in sliding parts

Posted: 24 Jul 2014 06:43 AM PDT

Researchers have discovered a previously unknown mechanism for wear in metals: a swirling, fluid-like microscopic behavior in a solid piece of metal sliding over another. The findings could be used to improve the durability of metal parts in numerous applications.

Chemist develops X-ray vision for quality assurance

Posted: 24 Jul 2014 06:43 AM PDT

A researcher has developed a method that uses X-rays for the rapid identification of substances present in an indeterminate powder. The new technique has the capacity to recognize advanced biological molecules such as proteins. The method therefore has enormous potential in both food production and the pharmaceutical industry, where it opens up new opportunities for the quality assurance of protein-based medicines, for example.

Paracetamol no better than placebo for lower back pain

Posted: 24 Jul 2014 06:40 AM PDT

Paracetamol is no better than placebo at speeding recovery from acute episodes of lower back pain or improving pain levels, function, sleep, or quality of life, according to the first large randomized trial to compare the effectiveness of paracetamol with placebo for low-back pain. The findings question the universal endorsement of paracetamol as the first choice painkiller for low-back pain, say the authors.

Unleashing the power of quantum dot triplets

Posted: 24 Jul 2014 06:40 AM PDT

Another step towards faster computers relies on three coherently coupled quantum dots used as quantum information units. Quantum computers have yet to materialize. Yet, scientists are making progress in devising suitable means of making such computers faster. One such approach relies on quantum dots-a kind of artificial atom, easily controlled by applying an electric field. A new study demonstrates that changing the coupling of three coherently coupled quantum dots (TQDs) with electrical impulses can help better control them.

Four-billion-year-old chemistry in cells today

Posted: 24 Jul 2014 06:40 AM PDT

Parts of the primordial soup in which life arose have been maintained in our cells today according to scientists. Research has revealed how cells in plants, yeast and very likely also in animals still perform ancient reactions thought to have been responsible for the origin of life -- some four billion years ago.

Nano-supercapacitors for electric cars

Posted: 24 Jul 2014 06:40 AM PDT

Innovative nano-material based supercapacitors are set to bring mass market appeal a good step closer to the lukewarm public interest in Germany. This movement is currently being motivated by the advancements in the state-of-the-art of this device.

Formula calculates thickness of bombproof concrete

Posted: 24 Jul 2014 06:40 AM PDT

A new type of steel-reinforced concrete protects buildings better from bomb attacks. Researchers have developed a formula to quickly calculate the concrete's required thickness. The material will be used in the One World Trade Center at Ground Zero.

New drugs to combat asthma, similar illnesses

Posted: 24 Jul 2014 06:40 AM PDT

Science and industry are collaborating to develop future pharmaceuticals for treating chronic inflammatory diseases. The medicines will combat immunological processes that have gone wrong. Statistics indicate that there are 300 million asthma sufferers worldwide, a further 600 million people living with chronic pneumonia and up to 30% of the global population contending with allergic rhinitis (allergic inflammation of the nasal airways).

Genome analysis helps in breeding more robust cows

Posted: 24 Jul 2014 06:37 AM PDT

Genome analysis of 234 bulls has put researchers on the trail of DNA variants which influence particular characteristics in breeding bulls. For example, two variants have proven responsible for disruptions to the development of embryos and for curly hair, which is disadvantageous because more ticks and parasites occur in curly hair than in short, straight hair. These are the first results of the large 1000 Bull Genomes project on which some 30 international researchers are collaborating.

Wireless home automation systems reveal more than you would think about user behavior

Posted: 24 Jul 2014 06:36 AM PDT

Home automation systems that control domestic lighting, heating, window blinds or door locks offer opportunities for third parties to intrude on the privacy of the inhabitants and gain considerable insight into their behavioral patterns.

One route to malaria drug resistance found

Posted: 24 Jul 2014 06:33 AM PDT

Researchers have uncovered a way the malaria parasite becomes resistant to an investigational drug. The discovery also is relevant for other infectious diseases including bacterial infections and tuberculosis. Fosmidomycin, an antibiotic, is being evaluated against malaria in phase 3 clinical trials in combination with other antimalarial drugs.

Hubble finds three surprisingly dry exoplanets: 'Hot Jupiters' had only one-tenth to one one-thousandth the amount of water predicted

Posted: 24 Jul 2014 06:28 AM PDT

Astronomers have gone looking for water vapor in the atmospheres of three planets orbiting stars similar to the Sun -- and have come up nearly dry. The three planets, known as HD 189733b, HD 209458b, and WASP-12b, are between 60 and 900 light-years away from Earth and were thought to be ideal candidates for detecting water vapor in their atmospheres because of their high temperatures where water turns into a measurable vapor.

Why don't genetically identical cells behave identically? Cellular noise

Posted: 24 Jul 2014 06:28 AM PDT

One researcher is like a mechanic for cells: he takes them apart to see how they function. He can tell you what part is like a gas pedal and which part is like the brakes. Now he's can show us why these brakes don't work the same even in cells that are genetically identical.

Greater odds of adverse childhood experiences in those with military service, study finds

Posted: 23 Jul 2014 01:20 PM PDT

Men and women who have served in the military have a higher prevalence of adverse childhood events (ACEs), suggesting that enlistment may be a way to escape adversity for some. ACEs can result in severe adult health consequences such as posttraumatic stress disorder, substance use and attempted suicide.

Unsuspected characteristics of new cystic fibrosis drugs found, offering potential paths to more effective therapies

Posted: 23 Jul 2014 12:20 PM PDT

A large phase 3 clinical trial for cystic fibrosis patients has concluded, showing that a combination of two new cystic fibrosis drugs modestly improved lung function and offered better health outcomes for some patients. Now, scientists have shown that one of these drugs counteracts the intended beneficial molecular effect of the other.

Gene inhibitor, salmon fibrin restore function lost in spinal cord injury in rodents

Posted: 23 Jul 2014 11:18 AM PDT

A therapy combining salmon fibrin injections into the spinal cord and injections of a gene inhibitor into the brain restored voluntary motor function impaired by spinal cord injury, scientists have found. In a study on rodents, researchers achieved this breakthrough by turning back the developmental clock in a molecular pathway critical to the formation of corticospinal tract nerve connections and providing a scaffold so that neuronal axons at the injury site could grow and link up again.

Sapronoses: Diseases of another kind, caused by pathogenic microorganisms

Posted: 23 Jul 2014 11:18 AM PDT

The drought that has the entire country in its grip is affecting more than the color of people's lawns. It may also be responsible for the proliferation of a heat-loving amoeba commonly found in warm freshwater bodies, such as lakes, rivers and hot springs, which the drought has made warmer than usual this year. Sapronoses are infectious diseases caused by pathogenic microorganisms that inhabit aquatic ecosystems and/or soil rather than a living host.

ScienceDaily: Health & Medicine News

ScienceDaily: Health & Medicine News


Pesticide linked to three generations of disease: Methoxychlor causes epigenetic changes

Posted: 24 Jul 2014 11:42 AM PDT

Researchers say ancestral exposures to the pesticide methoxychlor may lead to adult onset kidney disease, ovarian disease and obesity in future generations.

Linking microbial, immune environment in semen to HIV viral load, transmission

Posted: 24 Jul 2014 11:42 AM PDT

HIV infection re-shapes the relationship between semen bacteria and immune factors which in turn affects viral load, suggesting that the semen microbiome plays a role in sexual transmission of HIV, researchers report. While HIV is found in many body fluids, sexual transmission through semen is the most common route of infection.

DNA mostly 'junk?' Only 8.2 percent of human DNA is 'functional', study finds

Posted: 24 Jul 2014 11:16 AM PDT

Only 8.2 percent of human DNA is likely to be doing something important -- is 'functional' -- say researchers. This figure is very different from one given in 2012, when some scientists involved in the ENCODE (Encyclopedia of DNA Elements) project stated that 80% of our genome has some biochemical function.

Atomic structure of key muscle component revealed

Posted: 24 Jul 2014 11:16 AM PDT

Adding to the growing fundamental understanding of the machinery of muscle cells, a group of biophysicists describe -- in minute detail -- how actin filaments are stabilized at one of their ends to form a basic muscle structure called the sarcomere. With the help of many other proteins, actin molecules polymerize to form filaments that give rise to structures of many different shapes. The actin filaments have a polarity, with a plus and minus end, reflecting their natural tendency to gain or lose subunits when not stabilized.

Protein couple controls flow of information into brain's memory center

Posted: 24 Jul 2014 10:40 AM PDT

Neuroscientists have succeeded in providing new insights into how the brain works by analyzing tissue samples from mice to identify how two specific proteins, 'CKAMP44' and 'TARP Gamma-8', act upon the brain's memory center. Brain function depends on the active communication between nerve cells, known as neurons. For this purpose, neurons are woven together into a dense network where they constantly relay signals to one another.

Joblessness could kill you, but recessions could be good for your health

Posted: 24 Jul 2014 09:45 AM PDT

While previous studies of individuals have shown that employees who lose their jobs have a higher mortality rate, more comprehensive studies have shown, unexpectedly, that population mortality actually declines as unemployment rates increase. Researchers set out to better understand these seemingly contradictory findings.

Cancer: Treatment that prevents tumor metastasis identified in animal study

Posted: 24 Jul 2014 09:42 AM PDT

Metastasis, the strategy adopted by tumor cells to transform into an aggressive form of cancer, are often associated with a gloomy prognosis. Managing to block the metastasis or, even better, prevent their formation would be a giant step towards the fight against cancer. Researchers successfully performed this on models of human tumors in mice.

High school students in some schools smoking at same rate as adults

Posted: 24 Jul 2014 09:36 AM PDT

Cuyahoga County high school students are smoking tobacco products at the same rate as adults in the county, according to new data. In 2013, more than 22 percent, or one in five high school students, report use of any tobacco product within the prior 30 days.

Teens pay high psychiatric toll when raised in conditions of political conflict

Posted: 24 Jul 2014 08:25 AM PDT

Israeli youths exposed to protracted conflict suffer far higher levels of anxiety, phobia, fear, depression, obsessive-compulsive symptoms, and paranoia than their counterparts in the US. The largest cross-sectional empirical study of its kind, the research assessed youths exposed to terrorism, missile attacks, war, forced residential relocations, and military operations.

Metastatic brain tumor treatment could be on the horizon with use of SapC-DOPS

Posted: 24 Jul 2014 08:25 AM PDT

A new study has provided hope that previously studied SapC-DOPS could be used for treatment of brain cancer that has spread. "These results support the potential of SapC-DOPS for the diagnosis and therapy of primary and metastatic brain tumors which is critically needed to increase survival rates of patients with this illness," one researcher said.

Annual financial cost of COPD $36 billion in U.S.: CDC report

Posted: 24 Jul 2014 08:25 AM PDT

A new report outlines the total and state-specific medical and absenteeism costs of chronic obstructive pulmonary disease among adults in the United States, and lays out some projections to 2020. Chronic lower respiratory diseases, including COPD, are the third-leading cause of death in the United States. Close to 24 million US adults have evidence of impaired lung function, indicating an underdiagnosis of COPD. Smoking is a primary risk factor of COPD, and approximately 80% of COPD deaths can be attributed to smoking.

Seeing same GP at every visit will reduce emergency department attendance

Posted: 24 Jul 2014 08:25 AM PDT

Attendances at emergency departments can be reduced by enabling patients to see the same GP every time they visit their doctor's surgery. This is just one of several recommendations made in a report published. Other factors that also affect admission and attendances at emergency departments are: how easy it is for patients to access GP surgeries and primary care providers; the distance the patients live away from the emergency department; and the number of confusing options patients had for accessing emergency care.

Mechanism that clears excess of protein linked with Type 2 diabetes

Posted: 24 Jul 2014 07:42 AM PDT

In people who do not have Type 2 diabetes, autophagy prevents the accumulation of toxic forms of IAPP, researchers have found. In people with Type 2 diabetes, the process appears to not work properly, contributing to the destruction of beta cells. As the body's insulin producers, beta cells play a key role in maintaining healthy blood sugar levels.

Natural products from plants protect skin during cancer radiotherapy

Posted: 24 Jul 2014 07:42 AM PDT

Plant-derived natural product chemicals could offer protection to the skin from the harmful effects of gamma radiation during cancer radiotherapy, suggests research.

Background TV can be bad for kids

Posted: 24 Jul 2014 07:41 AM PDT

Leaving the television on can be detrimental to children's learning and development, according to a new study. Researchers found that background television can divert a child's attention from play and learning. Regardless of family demographics, parenting can act as a buffer against the impacts of background TV, the research team found.

Voice for radio? New research reveals it's in the cords

Posted: 24 Jul 2014 06:43 AM PDT

Unique vocal cord vibration patterns might be the secret behind a good radio voice, new research reveals. The world-first study filmed the vocal folds of 16 male radio performers, including announcers, broadcasters, newsreaders and voice-over artists and found their vocal folds move and close faster than non-broadcasters.

Experiments prove 'stemness' of individual immune memory cells

Posted: 24 Jul 2014 06:43 AM PDT

Specific individual immune cells, termed 'central memory T cells,' have all the essential characteristics of adult tissue stem cells, researchers have proven for the first time. Such cells can perpetuate themselves indefinitely and generate diverse offspring that can reconstitute "tissue" function. These findings indicate that it should be possible to fully restore specific immunity to pathogens in immunocompromised patients by substitution of small numbers of these T cells.

Paracetamol no better than placebo for lower back pain

Posted: 24 Jul 2014 06:40 AM PDT

Paracetamol is no better than placebo at speeding recovery from acute episodes of lower back pain or improving pain levels, function, sleep, or quality of life, according to the first large randomized trial to compare the effectiveness of paracetamol with placebo for low-back pain. The findings question the universal endorsement of paracetamol as the first choice painkiller for low-back pain, say the authors.

New drugs to combat asthma, similar illnesses

Posted: 24 Jul 2014 06:40 AM PDT

Science and industry are collaborating to develop future pharmaceuticals for treating chronic inflammatory diseases. The medicines will combat immunological processes that have gone wrong. Statistics indicate that there are 300 million asthma sufferers worldwide, a further 600 million people living with chronic pneumonia and up to 30% of the global population contending with allergic rhinitis (allergic inflammation of the nasal airways).

Detecting Salmonella in pork meat processing: New methods

Posted: 24 Jul 2014 06:37 AM PDT

Infections caused by foodborne microorganisms are an increasing public health burden. In a PhD project, new methods of characterizing and dectecting foodborne illness-causing Salmonella in pork meat processing and in bacteria in water, feed and food samples were studied.

One route to malaria drug resistance found

Posted: 24 Jul 2014 06:33 AM PDT

Researchers have uncovered a way the malaria parasite becomes resistant to an investigational drug. The discovery also is relevant for other infectious diseases including bacterial infections and tuberculosis. Fosmidomycin, an antibiotic, is being evaluated against malaria in phase 3 clinical trials in combination with other antimalarial drugs.

Why don't genetically identical cells behave identically? Cellular noise

Posted: 24 Jul 2014 06:28 AM PDT

One researcher is like a mechanic for cells: he takes them apart to see how they function. He can tell you what part is like a gas pedal and which part is like the brakes. Now he's can show us why these brakes don't work the same even in cells that are genetically identical.

New York law offers nurses more recognition, responsibility

Posted: 23 Jul 2014 03:08 PM PDT

If past experience is anything to go by, nurse practitioners in New York State are about to get a lot more recognition for their contributions to primary care. To improve the practice environment, managers should make efforts to establish a clear NP role within their organization and promote the visibility of NPs, an author says. Managers should also focus on improving the relationship between NPs and administrators and opening the channels of communications.

Medical student perceptions of health policy education improving, but 40% are still not satisfied, study shows

Posted: 23 Jul 2014 03:07 PM PDT

Students graduating from U.S. medical schools in 2012 feel they've received a better education in health policy issues than graduates surveyed in 2008, according to a multi-center study. The study applied a new framework for teaching and evaluating perceptions of training in health policy, first proposed by the authors in a 2011 perspective.

Greater odds of adverse childhood experiences in those with military service, study finds

Posted: 23 Jul 2014 01:20 PM PDT

Men and women who have served in the military have a higher prevalence of adverse childhood events (ACEs), suggesting that enlistment may be a way to escape adversity for some. ACEs can result in severe adult health consequences such as posttraumatic stress disorder, substance use and attempted suicide.

Unsuspected characteristics of new cystic fibrosis drugs found, offering potential paths to more effective therapies

Posted: 23 Jul 2014 12:20 PM PDT

A large phase 3 clinical trial for cystic fibrosis patients has concluded, showing that a combination of two new cystic fibrosis drugs modestly improved lung function and offered better health outcomes for some patients. Now, scientists have shown that one of these drugs counteracts the intended beneficial molecular effect of the other.

Gene inhibitor, salmon fibrin restore function lost in spinal cord injury in rodents

Posted: 23 Jul 2014 11:18 AM PDT

A therapy combining salmon fibrin injections into the spinal cord and injections of a gene inhibitor into the brain restored voluntary motor function impaired by spinal cord injury, scientists have found. In a study on rodents, researchers achieved this breakthrough by turning back the developmental clock in a molecular pathway critical to the formation of corticospinal tract nerve connections and providing a scaffold so that neuronal axons at the injury site could grow and link up again.

Sapronoses: Diseases of another kind, caused by pathogenic microorganisms

Posted: 23 Jul 2014 11:18 AM PDT

The drought that has the entire country in its grip is affecting more than the color of people's lawns. It may also be responsible for the proliferation of a heat-loving amoeba commonly found in warm freshwater bodies, such as lakes, rivers and hot springs, which the drought has made warmer than usual this year. Sapronoses are infectious diseases caused by pathogenic microorganisms that inhabit aquatic ecosystems and/or soil rather than a living host.

Dead body feeding larvae useful in forensic investigations

Posted: 23 Jul 2014 09:39 AM PDT

Non-biting blow fly Chrysomya megacephala is commonly found in dead bodies and is used in forensic investigations to determine the time of death, referred to as the post mortem interval. A report of synanthropic derived form of C. megacephala from Tamil Nadu is provided for the first time based on morphological features and molecular characterization through generation of DNA barcoding.

Protein evolution follows modular principle

Posted: 23 Jul 2014 09:39 AM PDT

Similarities between proteins reveal that their great diversity has arisen from smaller building blocks. Proteins consist of long chains of 20 different amino acid building blocks that fold into a characteristic three-dimensional structure. It is noteworthy that some modules, known as protein domains, occur more frequently than others. Scientists suspect that many of these domains share a common evolutionary origin.

Brown fat protects against diabetes, obesity in humans

Posted: 23 Jul 2014 09:39 AM PDT

People with higher levels of brown fat, or brown adipose tissue, in their bodies have better blood sugar control, higher insulin sensitivity and a better metabolism for burning fat stores, researchers have shown for the first time. The findings suggest that, because of the brown fat's ability to better regulate blood sugar, this could be a potential medical weapon against diabetes.

Ketamine can be a wonder drug for ER patients, physicians

Posted: 23 Jul 2014 08:41 AM PDT

For critically ill patients arriving at the emergency department, the drug ketamine can safely provide analgesia, sedation and amnesia for rapid, life-saving intubation, despite decades-old studies that suggested it raised intracranial pressure. A systematic review of 10 recent studies of what many emergency physicians regard as a 'wonder drug' has been recently published for review.

Researchers unlock protein puzzle using brightly hued dyes

Posted: 23 Jul 2014 08:12 AM PDT

By using brightly hued dyes, researchers discovered an innovative way to reveal where proteins touch each other, possibly leading to new treatments for cancer, arthritis, heart disease and even lung disease.

Statin use decreases risk of Barrett's esophagus, study shows

Posted: 23 Jul 2014 08:11 AM PDT

Statins, a class of drugs commonly used to lower cholesterol levels, significantly reduce a patient's risk of developing Barrett's esophagus, according to a new study. The protective effect of statins was especially significant among patients who were obese. Those with a body mass index greater than or equal to 30 had a 74 percent reduction in Barrett's esophagus.

Controlling childbirth pain tied to lower depression risk

Posted: 23 Jul 2014 08:09 AM PDT

Controlling pain during childbirth and post delivery is linked to reduced risk of postpartum depression, says a perinatal psychiatrist, based on a new study. The study showed postpartum depression rates doubled for women without pain control. Significant numbers of women have acute and chronic pain related to childbirth and need to consult with their physician if pain continues for several months.

Human parasite Leishmania is a probiotic for the fly that carries it

Posted: 23 Jul 2014 08:06 AM PDT

The Leishmania parasite, which causes the human disease leishmaniasis, acts as a probiotic in the insect that transmits it to humans, protecting them from bacterial disease, research shows. Around 12 million people are currently infected with Leishmaniasis worldwide, mostly in South America, Africa and Asia. It is estimated to kill 20-50,000 people per year. Sandflies transmit the parasite by feeding on an infected mammal and, if they survive long enough, feeding on another mammal, and passing the parasite on to them.

Physical work environment in hospitals affects nurses' job satisfaction, with implications for patient outcomes, health care costs

Posted: 23 Jul 2014 08:01 AM PDT

Architecture, interior design, and other physical aspects of their work environments can enhance early-career nurses' job satisfaction, a study has shown. The research team conducted a nationwide survey of RNs to examine the relationship between RNs' physical work environment and job satisfaction. They found that RNs who gave their physical work environments higher ratings were also more likely to report better workgroup cohesion, nurse-physician relations, workload, and other factors associated with job satisfaction.

Number of people susceptible to painful mosquito-borne virus increasing, says leading researcher

Posted: 23 Jul 2014 07:59 AM PDT

A leading researcher in chikungunya virus says many more people are at risk of getting infected now that mosquitoes in the U.S. are carrying the virus. At least 243 travel-related cases of chikungunya have been reported to the Centers for Disease Control and Prevention in 31 states, with the number expected to grow. The first case acquired in the United States was reported in Florida, seven months after the mosquito-borne virus was recognized in the Western Hemisphere.

Caffeine intake may worsen menopausal hot flashes, night sweats

Posted: 23 Jul 2014 07:59 AM PDT

An association between caffeine intake and more bothersome hot flashes and night sweats in postmenopausal women has been made by researchers. Approximately 85 percent of the U.S. population consumes some form of caffeine-containing beverage daily. Vasomotor symptoms (hot flashes and night sweats) are the most commonly reported menopausal symptoms, occurring in 79 percent of perimenopausal women and 65 percent of postmenopausal women.

In asthma, it's not just what you smell, but what you think you smell

Posted: 22 Jul 2014 01:41 PM PDT

Simply believing that an odor is potentially harmful can increase airway inflammation in asthmatics for at least 24 hours following exposure, research shows. The findings highlight the role that expectations can play in health-related outcomes.