الخميس، 12 يناير 2017

ScienceDaily: Top News

ScienceDaily: Top News


How stress may increase risk of heart disease and stroke

Posted: 11 Jan 2017 06:36 PM PST

Heightened activity in the amygdala -- a region of the brain involved in stress -- is associated with a greater risk of heart disease and stroke, according to a study that provides new insights into the possible mechanism by which stress can lead to cardiovascular disease in humans.

Incentive pay schemes can affect employee well-being

Posted: 11 Jan 2017 06:32 PM PST

Incentive-related pay schemes can stress rather than motivate employees, according to new research.

Most valuable colleagues: What the NBA can teach us about worker productivity

Posted: 11 Jan 2017 03:45 PM PST

Some employees could have a halo effect on their peers, according to new research. An individual's decisions regarding whether to smoke, how much to eat and whether to attend college can all be influenced by peer choices. In the same way, workplace productivity can spill over from one employee to another.

Bacterial protein structure could aid development of new antibiotics

Posted: 11 Jan 2017 03:45 PM PST

Bacterial cells have an added layer of protection, called the cell wall, that animal cells don't. Assembling this tough armor entails multiple steps, some of which are targeted by antibiotics like penicillin and vancomycin. Now researchers have provided the first close-up glimpse of a protein, called MurJ, which is crucial for building the bacterial cell wall and protecting it from outside attack. The findings could be used to develop new broad-spectrum antibiotics.

Researchers develop novel treatment to prevent graft-versus-host-disease

Posted: 11 Jan 2017 03:45 PM PST

Graft-versus-host-disease (GVHD) is the leading cause of non-relapse associated death in patients who receive stem cell transplants. In a new study, researchers show that a novel treatment can effectively inhibit the development of GVHD in mice and maintain the infection- and tumor-fighting capabilities of the immune system.

Pressures from grazers hastens ecosystem collapse from drought

Posted: 11 Jan 2017 03:44 PM PST

Ecosystem collapse from extreme drought can be significantly hastened by pressures placed on drought-weakened vegetation by grazers and fungal pathogens, a new study finds. The study's experimental evidence shows that the natural enemies of plants play a major role in lowering resilience to drought and preventing recovery afterward. The finding may be applicable to a wide range of ecosystems now threatened by climate-intensified drought, including marshes, mangroves, forests and grasslands.

Deciphering the beetle exoskeleton with nanomechanics

Posted: 11 Jan 2017 03:44 PM PST

Engineers have employed a creative way to identify the geometry and material properties of the fibers that comprise a beetle's exoskeleton. This work could ultimately uncover information that could guide the design and manufacturing of new and improved artificial materials through bio-mimicry.

New target for taming Ebola

Posted: 11 Jan 2017 03:44 PM PST

A team of scientists has identified a mechanism that appears to represent one way that host cells have evolved to outsmart infection by Ebola and other viruses.

How a Western diet leads to overeating and obesity

Posted: 11 Jan 2017 03:43 PM PST

More than two in three adults in the United States are considered overweight or obese, with substantial biomedical and clinical evidence suggesting that chronic overconsumption of a 'western diet' -- foods consisting high levels of sugars and fats -- is a major cause of this epidemic. New research now shows that chronic consumption of a western diet leads to overeating and obesity due to elevations in 'peripheral endocannabinoid signaling.'

Sketching out magnetism with electricity

Posted: 11 Jan 2017 03:41 PM PST

In a proof-of-concept study, researchers drew magnetic squares in a nonmagnetic material with an electrified pen and then "read" this magnetic doodle with X-rays.

Diet helps shed pounds, release toxins and reduce oxidative stress

Posted: 11 Jan 2017 03:41 PM PST

Research by exercise scientists has found that a balanced, protein-pacing, low-calorie diet that includes intermittent fasting not only achieves long-term weight loss, but also helps release toxins in the form of PCBs from the body fat stores, in addition to enhancing heart health and reducing oxidative stress.

Cost, technology issues are barriers to real-time cancer patient symptom reporting

Posted: 11 Jan 2017 03:40 PM PST

In a perspective article, a researcher addresses the need for – and the barriers preventing – electronic reporting of patients' symptoms between visits.

Genetic opposites attract when chimpanzees choose a mate

Posted: 11 Jan 2017 12:18 PM PST

Researchers find that chimpanzees are more likely to reproduce with mates whose genetic makeup most differs from their own. Many animals avoid breeding with parents, siblings and other close relatives, researchers say. But chimps are unusual in that even among virtual strangers they can tell genetically similar mates from more distant ones. Chimps are able to distinguish degrees of genetic similarity among unfamiliar mates many steps removed from them in their family tree.

Should biomedical graduate schools ignore the GRE?

Posted: 11 Jan 2017 12:18 PM PST

The Graduate Record Exam (GRE), which is required for admission to graduate and doctorate programs across the country, is not the best indicator for predicting a student's success while pursuing a doctorate in the experimental life sciences. And from that research, investigators recommend devaluing - if not eliminating altogether - the GRE from the applications process for biomedical PhD candidates.

Stem cells used to regenerate the external layer of a human heart

Posted: 11 Jan 2017 12:18 PM PST

A process using human stem cells can generate the cells that cover the external surface of a human heart -- epicardium cells -- according to a multidisciplinary team of researchers.

Strep spreads by harnessing immune defenses of those infected

Posted: 11 Jan 2017 12:18 PM PST

The bacteria that cause most cases of pneumonia worldwide secrete a toxin that helps them jump from one body to the next -- with help from the hosts' immune defenses.

Trust issues: Users more gullible when they customize their technology

Posted: 11 Jan 2017 12:18 PM PST

Cheery robots may give people the creeps and serious robots may actually ease anxiety depending on how users perceive the robot's role in their lives, according to an international team of researchers.

Do dogs of all ages respond equally to dog-directed speech?

Posted: 11 Jan 2017 12:18 PM PST

People tend to talk to dogs as though they are human babies. A new study shows that people speak more slowly and with a higher tone to dogs of all ages -- both adults and puppies -- and that puppies respond most readily to this dog-directed speech.

Report recommends new framework for estimating the social cost of carbon

Posted: 11 Jan 2017 12:18 PM PST

To estimate the social cost of carbon dioxide for use in regulatory impact analyses, the federal government should use a new framework that would strengthen the scientific basis, provide greater transparency, and improve characterization of the uncertainties of the estimates, suggests a new report.

Why better choices depend on 'libertarian paternalism'

Posted: 11 Jan 2017 12:18 PM PST

Nudging people toward better behavior through policy can be effective, but can face resistance if people feel their autonomy is threatened.

Release of water shakes Pacific plate at depth

Posted: 11 Jan 2017 12:14 PM PST

A team of seismologists analyzing the data from 671 earthquakes that occurred between 30 and 280 miles beneath the Earth's surface in the Pacific Plate as it descended into the Tonga Trench were surprised to find a zone of intense earthquake activity in the downgoing slab. The pattern of the activity along the slab provided strong evidence that the earthquakes are sparked by the release of water at depth.

Changing climate changes soils

Posted: 11 Jan 2017 10:38 AM PST

Researchers have used digital techniques to predict how one vital soil characteristic, soil organic carbon, may be altered by climate change.

A glimpse into the workings of the baby brain

Posted: 11 Jan 2017 10:28 AM PST

Neuroscientists have adapted their MRI scanner to make it easier to scan infants' brains as the babies watch movies featuring different types of visual input.

Paleontologists classify mysterious ancient cone-shaped sea creatures

Posted: 11 Jan 2017 10:28 AM PST

One branch on the tree of life is heavier as a team of scientists has determined what a bizarre group of extinct cone-shaped animals actually are. Known as hyoliths, these marine creatures evolved over 530 million years ago and are among the first known to have external skeletons. Long believed to be molluscs, a new study shows a stronger relationship to brachiopods -- a group with a rich fossil record though few species living today.

Scientists discover world's largest tropical peatland in remote Congo swamps

Posted: 11 Jan 2017 10:28 AM PST

A vast peatland in the Congo Basin has been mapped for the first time, revealing it to be the largest in the tropics. The new study found that the Cuvette Centrale peatlands in the central Congo Basin, which were unknown to exist five years ago, cover 145,500 square kilometres -- an area larger than England. They lock in 30 billion tonnes of carbon making the region one of the most carbon-rich ecosystems on Earth.

Physicists 'squeeze' light to cool microscopic drum below quantum limit

Posted: 11 Jan 2017 10:28 AM PST

Physicists have cooled a mechanical object to a temperature lower than previously thought possible, below the so-called 'quantum limit.'

'Marvel microbes' illuminate how cells became complex

Posted: 11 Jan 2017 10:28 AM PST

A newly discovered group of microbes provide new insights as to how complex cellular life emerged. The study provides new details of how, billions of years ago, complex cell types that comprise plants, fungi, but also animals and humans, gradually evolved from simpler microbial ancestors.

New genes identified that regulate the spread of cancers

Posted: 11 Jan 2017 10:28 AM PST

Researchers have discovered a new biological target for drugs to reduce the spread of tumours in cancer patients. The study with genetically modified mice found 23 genes that are involved in regulating the spread of cancers. The researchers showed that targeting one of these genes -- Spns2 -- led to a three-quarters reduction in tumor spread.

New laser based on unusual physics phenomenon could improve telecommunications, computing

Posted: 11 Jan 2017 10:27 AM PST

Researchers have demonstrated the world's first laser based on an unconventional wave physics phenomenon called bound states in the continuum. The technology could revolutionize the development of surface lasers, making them more compact and energy-efficient for communications and computing applications. The new BIC lasers could also be developed as high-power lasers for industrial and defense applications.

Can the 'greening' be greener?

Posted: 11 Jan 2017 10:27 AM PST

The EU introduced the new 'greening' instrument into the Common Agricultural Policy in 2015, with the intention to slow the rapid loss of biodiversity in agricultural areas. A group of scientists examined how effective the flagship greening measure called 'Ecological Focus Areas' actually is. Their conclusions are sobering: Ecological Focus Areas are implemented in a way that provides little benefit for biodiversity or farmers, and yet come at a high price to tax payers.

First look inside nanoscale catalysts shows 'defects' are useful

Posted: 11 Jan 2017 10:27 AM PST

Peering for the first time into the workings of tiny chemical catalysts, scientists observed that the 'defective' structure on their edges enhances their reactivity and effectiveness. This finding that could lead to the design of improved catalysts that make industrial chemical processes greener, by decreasing the amount of energy needed for chemical reactions, and preventing the formation of unwanted and potentially hazardous products.

new light shed on functioning of human gut bacteria

Posted: 11 Jan 2017 10:27 AM PST

Researchers shed new light on the functioning of human gut bacteria, revealing how nutrients are transported into the bacterial cell.

Gun violence in PG-13 movies continues to climb past R-rated films

Posted: 11 Jan 2017 10:11 AM PST

The amount of gun violence in top-grossing PG-13 movies has continued to exceed the gun violence in the biggest box-office R-rated films, an analysis shows. What increasingly differentiates the gun violence in PG-13 movies from those rated R is not just frequency but these films' 'erasure of the consequences' such as blood and suffering and the involvement of comic book-inspired heroes and antiheroes.

Superhero culture magnifies aggressive, not defending behaviors

Posted: 11 Jan 2017 10:11 AM PST

Children who frequently engage with superhero culture are more likely to be physically and relationally aggressive one year later and not more likely to be defenders of kids being picked on by bullies, new research concludes.

New therapeutic target against persistent viral infections

Posted: 11 Jan 2017 10:11 AM PST

Life is a question of balance, and the body is no exception. Expression levels of certain proteins can affect the immune system's ability to neutralize a virus. Type I interferons (IFN-I) are cytokines that were previously thought of as key contributors to the antiviral response, but emerging lines of evidence suggest that they may also participate in the establishment and maintenance of persistent viral infections.

Measuring how perovskite solar films efficiently convert light to power

Posted: 11 Jan 2017 10:11 AM PST

Researchers have directly shown that electrons generated when light strikes a well-oriented perovskite film are unrestricted by grain boundaries and travel long distances without deteriorating. Identification of this property, which is key to efficiently convert sunlight into electricity, could lead to more efficient solar panels.

Catching CRISPR in action: First all-atom simulation of genome editing in action

Posted: 11 Jan 2017 10:11 AM PST

Scientists have performed the first all-atom molecular dynamics simulations of Cas9-catalyzed DNA cleavage in action. The simulations shed light on the process of Cas9 genome editing and helped resolve controversies about specific aspects of the cutting.

DNA duplicator small enough to hold in your hand

Posted: 11 Jan 2017 10:11 AM PST

Engineers have developed a new method for duplicating DNA that makes devices small enough to hold in your hand that are capable of identifying infectious agents before symptoms appear.

High-sugar diet programs a short lifespan in flies

Posted: 11 Jan 2017 10:08 AM PST

Flies with a history of eating a high sugar diet live shorter lives, even after their diet improves. This is because the unhealthy diet drives long-term reprogramming of gene expression, according to a team of researchers.

National salt reduction strategy is cost-effective 'best buy' for 183 countries worldwide

Posted: 11 Jan 2017 10:07 AM PST

A new global study projects that a government-supported intervention to reduce national salt consumption by 10 percent over 10 years would be a highly cost-effective 'best buy' for preventing cardiovascular disease across 183 countries worldwide. Government-supported policy projected to be a highly cost-effective way to reduce salt consumption and gain healthy years lost to cardiovascular disease

High dietary red meat intake linked to common bowel condition diverticulitis

Posted: 11 Jan 2017 09:28 AM PST

Replacing one daily portion with poultry or fish may lower risk, findings suggest.

Walking the tightrope: The balance between helping patients now without risking the future

Posted: 11 Jan 2017 08:53 AM PST

Antibiotic use represents a special challenge, in which too much of a good thing can be dangerous to public health as a whole. The fight against a common, costly, hospital-acquired infection known as Clostridium difficile, or C. diff offers an illuminating case study in the area of so-called antibiotic stewardship.

Contrary to decades of hype, curcumin alone is unlikely to boost health

Posted: 11 Jan 2017 08:08 AM PST

Curcumin, a compound in turmeric, continues to be hailed as a natural treatment for a wide range of health conditions, including cancer and Alzheimer's disease. But a new review of the scientific literature on curcumin has found it's probably not all it's ground up to be. The report instead cites evidence that, contrary to numerous reports, the compound has limited -- if any -- therapeutic benefit.

Our galaxy's black hole is spewing out planet-size 'spitballs'

Posted: 11 Jan 2017 08:08 AM PST

Every few thousand years, an unlucky star wanders too close to the black hole at the center of the Milky Way. The black hole's powerful gravity rips the star apart, sending a long streamer of gas whipping outward. That would seem to be the end of the story, but it's not. New research shows that not only can the gas gather itself into planet-size objects, but those objects then are flung throughout the galaxy in a game of cosmic 'spitball.'

Farthest stars in Milky Way might be ripped from another galaxy

Posted: 11 Jan 2017 08:08 AM PST

The 11 farthest known stars in our galaxy are located about 300,000 light-years from Earth, well outside the Milky Way's spiral disk. New research shows that half of those stars might have been ripped from another galaxy: the Sagittarius dwarf. Moreover, they are members of a lengthy stream of stars extending one million light-years across space, or 10 times the width of our galaxy.

New type of monitoring provides information about the life of bacteria in microdroplets

Posted: 11 Jan 2017 08:08 AM PST

In the future, it will be possible to carry out tests of new drugs on bacteria much more efficiently using microfluidic devices, since each of the hundreds and thousands of droplets moving through the microchannels can act as separate incubators. So far, however, there has been no quick or accurate method of assessing the oxygen conditions in individual microdroplets.

Customers who receive genetic health data not alarmed by results, find information useful

Posted: 11 Jan 2017 07:39 AM PST

As consumers have been able to learn more about their genetic makeup in recent years through personal genomic testing, one big criticism has been that without someone to interpret it, the health information could be harmful to the receivers.

For men with prostate cancer, emotional distress may lead to more aggressive treatment

Posted: 11 Jan 2017 07:39 AM PST

The anxiety many men experience after being diagnosed with prostate cancer may lead them to choose potentially unnecessary treatment options, researchers report.

Bronchial carcinoma: Added benefit of crizotinib not proven

Posted: 11 Jan 2017 07:29 AM PST

The dossier contains no data or no suitable data on ROS1-positive, advanced non-small cell lung cancer. Results on ALK-positive tumors are not applicable.

New method to remove nickel from contaminated seawater

Posted: 11 Jan 2017 07:29 AM PST

The same deposit that builds up in many tea kettles or water pipes in areas where calcium-rich water is the norm might be just the (cheap) ticket to rid contaminated seawater of toxic metals.

Changes to hospital electronic health records could improve care of patients on warfarin

Posted: 11 Jan 2017 07:29 AM PST

Using electronic health records can improve the care patients on warfarin receive after they leave the hospital and eliminate potential confusion among care providers and pharmacists, research concludes.

Tumor-seeking salmonella treats brain tumors

Posted: 11 Jan 2017 07:29 AM PST

Genetic tweaks to salmonella turn the bacteria into cancer-seeking missiles that produce self-destruct orders deep within tumors. Tests in rat models with extreme cases of the disease showed a remarkable 20 percent survival rate over 100 days -- roughly equivalent to 10 human years -- with the tumors going into complete remission.

A novel cancer immunotherapy shows early promise in preclinical studies

Posted: 11 Jan 2017 07:29 AM PST

Scientists report that GARP, a TGF-beta cell surface receptor, could be a novel diagnostic marker for breast, colon, and lung cancer. An antibody-based therapy targeting GARP prevented metastasis to the lung in a mouse model of breast cancer. Targeting GARP with an antibody could represent a novel addition to established immunotherapies that 'wake up' the immune system so that it can fight cancer.

Surprise advance in the treatment of adult cancers

Posted: 11 Jan 2017 07:29 AM PST

An epigenetic modification that might be the cause of 15% of adult cancers of the throat linked to alcohol and tobacco use was identified. This discovery was unexpected since it seemed highly improbable that this kind of alterations of the epigenome found in children could also target an epithelial tumor like throat cancer that occurs only in adults.

Updated classification system captures many more people at risk for heart attack

Posted: 11 Jan 2017 07:29 AM PST

Experts have published a suggested new plan for a five-stage system of classifying the risk of heart attack in those with heart disease, one they say puts much-needed and long-absent focus on the risks faced by millions of Americans who pass so-called stress tests or have less obvious or earlier-stage danger signs.

Nature's weaving formula used to engineer advanced functional materials

Posted: 11 Jan 2017 07:29 AM PST

For the first time, biomedical engineers have woven a 'smart' fabric that mimics the sophisticated and complex properties of one nature's ingenious materials, the bone tissue periosteum. Having achieved proof of concept, the researchers are now ready to produce fabric prototypes for a range of advanced functional materials that could transform the medical, safety and transport sectors.

New Colombian plant discovered honors Colombian president

Posted: 11 Jan 2017 07:29 AM PST

A new plant species from Northeastern Colombia has been named Espeletia praesidentis, in honor of efforts made by Colombian President Juan Manuel Santos to build peace in his country after over five decades of conflict.

How to inflate a huge hardened concrete shell

Posted: 11 Jan 2017 07:29 AM PST

An alternative for resource intensive formwork for the construction of concrete domes has been developed. It is now used in a test dome for the Austrian Federal Railways Infrastructure.

Psychology: Playful people are at an advantage

Posted: 11 Jan 2017 07:28 AM PST

Adults can positively utilise their inclination towards playfulness in many situations. They are good at observing, can easily see things from new perspectives, and can turn monotonous tasks into something interesting. At the same time, playfulness should not be equated with humor. Instead we need a new vocabulary to describe it, write psychologists.

Looking for life in all the right places, with the right tool

Posted: 11 Jan 2017 07:28 AM PST

Researchers have invented a range of instruments from giant telescopes to rovers to search for life in outer space, but so far, these efforts have yielded no definitive evidence that it exists beyond Earth. Now scientists have developed a new tool that can look for signs of life with 10,000 times more sensitivity than instruments carried on previous spaceflight missions.

ScienceDaily: Health & Medicine News

ScienceDaily: Health & Medicine News


How stress may increase risk of heart disease and stroke

Posted: 11 Jan 2017 06:36 PM PST

Heightened activity in the amygdala -- a region of the brain involved in stress -- is associated with a greater risk of heart disease and stroke, according to a study that provides new insights into the possible mechanism by which stress can lead to cardiovascular disease in humans.

Bacterial protein structure could aid development of new antibiotics

Posted: 11 Jan 2017 03:45 PM PST

Bacterial cells have an added layer of protection, called the cell wall, that animal cells don't. Assembling this tough armor entails multiple steps, some of which are targeted by antibiotics like penicillin and vancomycin. Now researchers have provided the first close-up glimpse of a protein, called MurJ, which is crucial for building the bacterial cell wall and protecting it from outside attack. The findings could be used to develop new broad-spectrum antibiotics.

Researchers develop novel treatment to prevent graft-versus-host-disease

Posted: 11 Jan 2017 03:45 PM PST

Graft-versus-host-disease (GVHD) is the leading cause of non-relapse associated death in patients who receive stem cell transplants. In a new study, researchers show that a novel treatment can effectively inhibit the development of GVHD in mice and maintain the infection- and tumor-fighting capabilities of the immune system.

New target for taming Ebola

Posted: 11 Jan 2017 03:44 PM PST

A team of scientists has identified a mechanism that appears to represent one way that host cells have evolved to outsmart infection by Ebola and other viruses.

How a Western diet leads to overeating and obesity

Posted: 11 Jan 2017 03:43 PM PST

More than two in three adults in the United States are considered overweight or obese, with substantial biomedical and clinical evidence suggesting that chronic overconsumption of a 'western diet' -- foods consisting high levels of sugars and fats -- is a major cause of this epidemic. New research now shows that chronic consumption of a western diet leads to overeating and obesity due to elevations in 'peripheral endocannabinoid signaling.'

Diet helps shed pounds, release toxins and reduce oxidative stress

Posted: 11 Jan 2017 03:41 PM PST

Research by exercise scientists has found that a balanced, protein-pacing, low-calorie diet that includes intermittent fasting not only achieves long-term weight loss, but also helps release toxins in the form of PCBs from the body fat stores, in addition to enhancing heart health and reducing oxidative stress.

Cost, technology issues are barriers to real-time cancer patient symptom reporting

Posted: 11 Jan 2017 03:40 PM PST

In a perspective article, a researcher addresses the need for – and the barriers preventing – electronic reporting of patients' symptoms between visits.

Stem cells used to regenerate the external layer of a human heart

Posted: 11 Jan 2017 12:18 PM PST

A process using human stem cells can generate the cells that cover the external surface of a human heart -- epicardium cells -- according to a multidisciplinary team of researchers.

Strep spreads by harnessing immune defenses of those infected

Posted: 11 Jan 2017 12:18 PM PST

The bacteria that cause most cases of pneumonia worldwide secrete a toxin that helps them jump from one body to the next -- with help from the hosts' immune defenses.

New genes identified that regulate the spread of cancers

Posted: 11 Jan 2017 10:28 AM PST

Researchers have discovered a new biological target for drugs to reduce the spread of tumours in cancer patients. The study with genetically modified mice found 23 genes that are involved in regulating the spread of cancers. The researchers showed that targeting one of these genes -- Spns2 -- led to a three-quarters reduction in tumor spread.

new light shed on functioning of human gut bacteria

Posted: 11 Jan 2017 10:27 AM PST

Researchers shed new light on the functioning of human gut bacteria, revealing how nutrients are transported into the bacterial cell.

New therapeutic target against persistent viral infections

Posted: 11 Jan 2017 10:11 AM PST

Life is a question of balance, and the body is no exception. Expression levels of certain proteins can affect the immune system's ability to neutralize a virus. Type I interferons (IFN-I) are cytokines that were previously thought of as key contributors to the antiviral response, but emerging lines of evidence suggest that they may also participate in the establishment and maintenance of persistent viral infections.

DNA duplicator small enough to hold in your hand

Posted: 11 Jan 2017 10:11 AM PST

Engineers have developed a new method for duplicating DNA that makes devices small enough to hold in your hand that are capable of identifying infectious agents before symptoms appear.

High-sugar diet programs a short lifespan in flies

Posted: 11 Jan 2017 10:08 AM PST

Flies with a history of eating a high sugar diet live shorter lives, even after their diet improves. This is because the unhealthy diet drives long-term reprogramming of gene expression, according to a team of researchers.

National salt reduction strategy is cost-effective 'best buy' for 183 countries worldwide

Posted: 11 Jan 2017 10:07 AM PST

A new global study projects that a government-supported intervention to reduce national salt consumption by 10 percent over 10 years would be a highly cost-effective 'best buy' for preventing cardiovascular disease across 183 countries worldwide. Government-supported policy projected to be a highly cost-effective way to reduce salt consumption and gain healthy years lost to cardiovascular disease

High dietary red meat intake linked to common bowel condition diverticulitis

Posted: 11 Jan 2017 09:28 AM PST

Replacing one daily portion with poultry or fish may lower risk, findings suggest.

Walking the tightrope: The balance between helping patients now without risking the future

Posted: 11 Jan 2017 08:53 AM PST

Antibiotic use represents a special challenge, in which too much of a good thing can be dangerous to public health as a whole. The fight against a common, costly, hospital-acquired infection known as Clostridium difficile, or C. diff offers an illuminating case study in the area of so-called antibiotic stewardship.

Contrary to decades of hype, curcumin alone is unlikely to boost health

Posted: 11 Jan 2017 08:08 AM PST

Curcumin, a compound in turmeric, continues to be hailed as a natural treatment for a wide range of health conditions, including cancer and Alzheimer's disease. But a new review of the scientific literature on curcumin has found it's probably not all it's ground up to be. The report instead cites evidence that, contrary to numerous reports, the compound has limited -- if any -- therapeutic benefit.

New type of monitoring provides information about the life of bacteria in microdroplets

Posted: 11 Jan 2017 08:08 AM PST

In the future, it will be possible to carry out tests of new drugs on bacteria much more efficiently using microfluidic devices, since each of the hundreds and thousands of droplets moving through the microchannels can act as separate incubators. So far, however, there has been no quick or accurate method of assessing the oxygen conditions in individual microdroplets.

Customers who receive genetic health data not alarmed by results, find information useful

Posted: 11 Jan 2017 07:39 AM PST

As consumers have been able to learn more about their genetic makeup in recent years through personal genomic testing, one big criticism has been that without someone to interpret it, the health information could be harmful to the receivers.

For men with prostate cancer, emotional distress may lead to more aggressive treatment

Posted: 11 Jan 2017 07:39 AM PST

The anxiety many men experience after being diagnosed with prostate cancer may lead them to choose potentially unnecessary treatment options, researchers report.

Bronchial carcinoma: Added benefit of crizotinib not proven

Posted: 11 Jan 2017 07:29 AM PST

The dossier contains no data or no suitable data on ROS1-positive, advanced non-small cell lung cancer. Results on ALK-positive tumors are not applicable.

Changes to hospital electronic health records could improve care of patients on warfarin

Posted: 11 Jan 2017 07:29 AM PST

Using electronic health records can improve the care patients on warfarin receive after they leave the hospital and eliminate potential confusion among care providers and pharmacists, research concludes.

Tumor-seeking salmonella treats brain tumors

Posted: 11 Jan 2017 07:29 AM PST

Genetic tweaks to salmonella turn the bacteria into cancer-seeking missiles that produce self-destruct orders deep within tumors. Tests in rat models with extreme cases of the disease showed a remarkable 20 percent survival rate over 100 days -- roughly equivalent to 10 human years -- with the tumors going into complete remission.

A novel cancer immunotherapy shows early promise in preclinical studies

Posted: 11 Jan 2017 07:29 AM PST

Scientists report that GARP, a TGF-beta cell surface receptor, could be a novel diagnostic marker for breast, colon, and lung cancer. An antibody-based therapy targeting GARP prevented metastasis to the lung in a mouse model of breast cancer. Targeting GARP with an antibody could represent a novel addition to established immunotherapies that 'wake up' the immune system so that it can fight cancer.

Surprise advance in the treatment of adult cancers

Posted: 11 Jan 2017 07:29 AM PST

An epigenetic modification that might be the cause of 15% of adult cancers of the throat linked to alcohol and tobacco use was identified. This discovery was unexpected since it seemed highly improbable that this kind of alterations of the epigenome found in children could also target an epithelial tumor like throat cancer that occurs only in adults.

Updated classification system captures many more people at risk for heart attack

Posted: 11 Jan 2017 07:29 AM PST

Experts have published a suggested new plan for a five-stage system of classifying the risk of heart attack in those with heart disease, one they say puts much-needed and long-absent focus on the risks faced by millions of Americans who pass so-called stress tests or have less obvious or earlier-stage danger signs.

Testing breast milk for cannabinoids

Posted: 11 Jan 2017 07:28 AM PST

With the legalization of medical and recreational marijuana spreading across the country, the drug's use is reportedly increasing among pregnant women. It stands to reason that many of these women will continue to use marijuana after they give birth. Now researchers have developed a new method to help determine what this means for infants' potential exposure to the active compounds in marijuana in breast milk.

Researchers find a potential target for anti-Alzheimer treatments

Posted: 11 Jan 2017 06:35 AM PST

Scientists have identified a gene that may provide a new starting point for developing treatments for Alzheimer's disease (AD). The USP9 gene has an indirect influence on the so-called tau protein, which is believed to play a significant role in the onset of Alzheimer's disease. This discovery may open a new door to developing active ingredients to treat Alzheimer's disease.

Remembering where to get high

Posted: 11 Jan 2017 06:35 AM PST

Addiction-related memories are exceptionally strong and stable, suggesting that addictive drugs remodel the brain's circuitry in a prominent and lasting way. In the past decade, researchers have used mouse models to unravel how cellular changes in the nucleus accumbens (NAc), a brain structure involved in action selection associated with arousal and reward, may contribute to addiction-related behavior. Whereas neuronal remodeling in the NAc explains a wide range of addictive behaviors, it is not required for all of them, according to a study.

Our senses can't learn under stress

Posted: 11 Jan 2017 06:34 AM PST

Stress is part of our everyday lives. While some thrive on it, it makes others sick. But what does stress do to our senses?

Blood test may help predict confusion after surgery

Posted: 11 Jan 2017 06:34 AM PST

Many people experience an extended period of confusion when they awake after surgery. This acute confusional state, called delirium, particularly affects older adults and poses an important clinical challenge as it can lead to greater postoperative complications and may extend hospitalization.

Sudden drop in outdoor temperature increases the risk of respiratory infections

Posted: 11 Jan 2017 06:34 AM PST

You can pretty much put a mark in your calendar for when the annual flu epidemic begins. Using 20,000 virus samples and weather statistics, researchers have now discovered more details about how outdoor temperature and flu outbreaks are linked.

New material in the fight against hospital-acquired infections

Posted: 11 Jan 2017 06:19 AM PST

Researchers have developed a new light-activated antimicrobial material for use in the fight against the most common hospital infections.

Intensive weight loss does not cause major health problems for female fitness competitors

Posted: 11 Jan 2017 06:19 AM PST

Worries about the potential negative consequences of fat loss regimens for aesthetic purposes in normal weight females have been surfacing in the media. This has taken place regardless of the lack of longitudinal studies on this kind of diets. Now researchers have published a study that shows for the first time what effects an intensive weight reduction had in rather a large group of normal weight females.

Antidepressant use increases hip fracture risk among elderly

Posted: 11 Jan 2017 06:19 AM PST

Antidepressant use nearly doubles the risk of hip fracture among community-dwelling persons with Alzheimer's disease, according to a new study. The increased risk was highest at the beginning of antidepressant use and remained elevated even 4 years later.

Tucatinib (ONT-380) progressing in pivotal trial against HER2+ breast cancer

Posted: 11 Jan 2017 06:14 AM PST

Twenty-seven percent of 50 heavily pretreated patients with stage IV HER2+ breast cancer saw clinical benefit from the drug Tucatinib (ONT-380) , with at least 'stable disease' at 24 or more weeks after the start of treatment.

Using E. coli to detect hormone disruptors in the environment

Posted: 11 Jan 2017 06:14 AM PST

Endocrine disrupting chemicals (EDCs) have been implicated in the development of obesity, diabetes and cancer and are found in a wide array of products including pesticides, plastics and pharmaceuticals. EDCs are potentially harmful, even at low concentrations, equal in some cases to mere milligrams dissolved in in a swimming pool full of water. Now researchers report that they can quickly detect environmentally relevant concentrations of EDCs using engineered E. coli bacteria.

Nutritional quality of kids' menus at chain restaurants not improving

Posted: 11 Jan 2017 06:14 AM PST

US chain restaurants participating in an initiative to improve the nutritional quality of their children's menus have made no significant changes compared with restaurants not participating in the program.

Rural dementia: We need to talk

Posted: 11 Jan 2017 06:14 AM PST

English research into the experience of dementia in farming and farming families, and its impact on their businesses and home lives, has identified four areas of concern which need to be addressed if dementia in the countryside is to be managed. It is the first time that research has addressed this issue in farming.

Scientists pave the way for enhanced detection and treatment of vascular graft infections

Posted: 11 Jan 2017 06:14 AM PST

A study reports the detrimental aftereffects of infected grafts, including the formation of biofilms that can shelter bacteria and function as a source of recurrent infection. This new research should enable researchers to develop better strategies to diagnose and manage vascular graft infections.

More older Americans using cannabis, underscoring need for research

Posted: 11 Jan 2017 06:14 AM PST

Cannabis use among older adults in the US is on the rise, yet there is currently a lack of biomedical, clinical, and public health research to inform policy related to this trend, according to a new article.

First study to show chair yoga as effective alternative treatment for osteoarthritis

Posted: 11 Jan 2017 06:14 AM PST

The first randomized controlled trial to examine the effects of chair yoga on pain and physical function in older adults with osteoarthritis is proving to be an effective way to reduce pain and improve quality of life while avoiding pharmacologic treatment or adverse events for the millions who suffer from the disease in their lower extremities (hip, knee, ankle or foot).

Pumping iron is good for the heart, researchers show

Posted: 11 Jan 2017 06:14 AM PST

Just one session of interval weight-training can improve the risk of Type 2 diabetes complications, according to a new study. This is encouraging news for those starting the New Year with good intentions.

Legal or not, marijuana can increase the risk of developing alcohol use disorders

Posted: 10 Jan 2017 04:49 PM PST

Alcohol use disorders (AUDs) develop with time and in stages. Following the initiation of drinking, some people progress to problem drinking, and then develop a "cluster" of specific problems to comprise an AUD. However, not all stages of AUD development have been studied equally. This report examines high-risk families to understand underlying influences across multiple stages of AUD development.

Air pollution and lack of physical activity pose competing threats to children in China

Posted: 10 Jan 2017 04:46 PM PST

Health workers and policymakers need to find ways to address poor air quality and lack of exercise among children in China so that children can be more physically active without suffering the health risks caused by exposure to air pollution.

Stool samples from the Inuit of Nunavut: Study documents their 'gut microbiome'

Posted: 10 Jan 2017 12:13 PM PST

Since 2012, doctoral student Catherine Girard has collected stool samples from the Inuit of Nunavut. In a new study, she documents for the first time their 'gut microbiome' -- with surprising results.

Normal ranges for testosterone levels defined

Posted: 10 Jan 2017 12:13 PM PST

A large study of more than 9,000 men has established harmonized reference ranges for total testosterone in men that when applied to assays that have been appropriately calibrated will effectively enable clinicians to make a correct diagnosis of hypogonadism, according to a new study.