ScienceDaily: Health & Medicine News

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• Genetically engineered compound for back pain falls short
• Giving preventive drug to men at high risk for HIV would be cost-effective, study shows
• Nano-syringe delivers combination, targeted brain cancer therapy
• Mechanical tissue resuscitation technology shows promise preventing cell death
• Off-label prescribing of medications is common, Canadian study suggests
• Pill reduced number of multiple sclerosis lesions in Phase II trial
• Study dusts sugar coating off little-known regulation in cells
• Nearly one in four grandparents store prescription medicines where children can easily find them
• Diet fad of 'eating through the nose' could be a nightmare, nutrition expert says
• Coronary stents not harmful to patients with history of metal allergy, study suggests
• Neural stem cell regulator identified: Lack of regulator can cause neural tube defects
• Football-related catastrophic brain injuries on the rise
• Potential treatment for lethal childhood leukemia: Inhibiting two related enzymes significantly improves survival in mouse model
• Further evidence found of disturbed immune system in autism
• More baby boomers facing old age alone
• New method may help detect marker for Alzheimer's disease earlier
• Metformin can substantially reduce the risk of Parkinson's disease in diabetes, study suggests
• Gene with a key role in neuronal survival identified
• Aesthetic appeal may have neurological link to contemplation and self-assessment
• How Parkinson's disease starts and spreads

Genetically engineered compound for back pain falls short Posted: 16 Apr 2012 03:58 PM PDT Despite the great promise that injecting a new type of anti-inflammatory pain medicine into the spine could relieve the severe leg and lower back pain of sciatica, a new study has found that the current standard of care with steroid injections still does better.

Giving preventive drug to men at high risk for HIV would be cost-effective, study shows Posted: 16 Apr 2012 03:57 PM PDT A once-a-day pill to help prevent HIV infection could significantly reduce the spread of AIDS, but only makes economic sense if used in select, high-risk groups, researchers conclude in a new study.

Nano-syringe delivers combination, targeted brain cancer therapy Posted: 16 Apr 2012 01:58 PM PDT Nanomedicine researchers have developed a way to selectively kill brain cancer cells by using a tiny syringe to deliver a combination of chemotherapy drugs directly into the cells.

Mechanical tissue resuscitation technology shows promise preventing cell death Posted: 16 Apr 2012 01:58 PM PDT Researchers seeking a successful treatment for traumatic brain injury have found that the size and extent of damaged tissue can be reduced by using a new device to prevent cell death.

Off-label prescribing of medications is common, Canadian study suggests Posted: 16 Apr 2012 01:56 PM PDT A study evaluating off-label prescribing of medications in a primary care network in Canada suggests the practice is common, although it varies by medication, patient and physician characteristics, according to a new report.

Pill reduced number of multiple sclerosis lesions in Phase II trial Posted: 16 Apr 2012 01:56 PM PDT An investigational oral drug called ONO-4641 reduced the number of lesions in people with multiple sclerosis, according to the results of a phase two clinical trial.

Study dusts sugar coating off little-known regulation in cells Posted: 16 Apr 2012 12:40 PM PDT O-GlcNAc regulatory system adds complexity in cell regulation, could eventually provide new drug targets.

Nearly one in four grandparents store prescription medicines where children can easily find them Posted: 16 Apr 2012 12:04 PM PDT Unintentional poisonings from medicines cause more emergency room visits for young children each year than do car accidents. But nearly 1 of every 4 grandparents says that they store prescription medicines in easy-access ways, according to a new poll.

Diet fad of 'eating through the nose' could be a nightmare, nutrition expert says Posted: 16 Apr 2012 12:01 PM PDT What should be a fairy-tale day — a woman's wedding — could turn into a nightmare for a bride-to-be who goes on a new feeding-tube diet to lose 20 pounds fast, says an expert.

Coronary stents not harmful to patients with history of metal allergy, study suggests Posted: 16 Apr 2012 10:04 AM PDT Cardiologists have long grappled with how to best manage patients with coronary artery disease who report skin hypersensitivity to nickel or other metal components found in stents -- small tubes placed in narrowed or weakened arteries to help improve blood flow to the heart. But new research may help allay these concerns.

Neural stem cell regulator identified: Lack of regulator can cause neural tube defects Posted: 16 Apr 2012 10:04 AM PDT Researchers have found that lack of a specific gene can interrupt neural tube closure.

Football-related catastrophic brain injuries on the rise Posted: 16 Apr 2012 10:03 AM PDT Catastrophic brain injuries associated with full-contact football appear to be rising, especially among high school students, according to a new report.

Potential treatment for lethal childhood leukemia: Inhibiting two related enzymes significantly improves survival in mouse model Posted: 16 Apr 2012 09:53 AM PDT Researchers have demonstrated that two related enzymes -- phosphoinositide-3 kinase gamma and delta -- play a key role in the development of T-cell acute lymphoblastic leukemia, a highly aggressive childhood leukemia that is difficult to treat. The study also showed that a dual PI3K gamma/delta inhibitor can significantly prolong survival in a mouse model of the disease.

Further evidence found of disturbed immune system in autism Posted: 16 Apr 2012 09:52 AM PDT One of the largest studies of its kind to date found disturbed levels of cytokines in the plasma of children with autism disorder: in particular, five related to the T-helper cell immune system and three involved in hematopoiesis.

More baby boomers facing old age alone Posted: 16 Apr 2012 09:51 AM PDT Startling new statistics paint a bleak future for the largest generation in history, the baby boomers, as they cross into old age.

New method may help detect marker for Alzheimer's disease earlier Posted: 16 Apr 2012 08:50 AM PDT Use of a new drug to detect the beta-amyloid plaques in the brain that are hallmark signs of Alzheimer's disease may help doctors diagnose the disease earlier.

Metformin can substantially reduce the risk of Parkinson's disease in diabetes, study suggests Posted: 16 Apr 2012 08:30 AM PDT A major 12-year study based on a Taiwanese population cohort has demonstrated that not only does diabetes increase the risk of developing Parkinson's disease more than twofold, the use of sulfonylureas, commonly used as treatment for diabetes, increases the risk further by about 57 percent. This study also found that by including metformin in the therapy, no increased risk in developing Parkinson's disease was recorded.

Gene with a key role in neuronal survival identified Posted: 16 Apr 2012 07:04 AM PDT Researchers have identified the fundamental role played by the Nurr1 gene in neuron survival associated with synaptic activity. The discovery allows scientists to study a new target that could help to understand the relationship between alterations in neural connections, which are known to cause early cognitive deficit, and the neurodegeneration characteristic of Alzheimer's disease.

Aesthetic appeal may have neurological link to contemplation and self-assessment Posted: 16 Apr 2012 06:51 AM PDT A network of brain regions which is activated during intense aesthetic experience overlaps with the brain network associated with inward contemplation and self-assessment, researchers have found. Their study sheds new light on the nature of the aesthetic experience, which appears to integrate sensory and emotional reactions in a manner linked with their personal relevance.

How Parkinson's disease starts and spreads Posted: 16 Apr 2012 06:50 AM PDT Injection of a small amount of clumped protein triggers a cascade of events leading to a Parkinson's-like disease in mice, according to a new article.

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