ScienceDaily: Health & Medicine News

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• New compound holds promise for treating Duchenne MD, other inherited diseases
• Successful transplant of patient-derived stem cells into mice with muscular dystrophy
• Injecting life-saving oxygen into a vein
• New vaccine for nicotine addiction
• Researchers delve into airborne particulates
• Regulation of telomerase in stem cells and cancer cells
• Immune response to heart attack worsens atherosclerosis, increases future risk
• Scientists measure soot particles in flight
• Easier way to make new drug compounds
• Parkinson’s disease gene identified with help of Saskatchewan Mennonite families
• Brain scans detect early signs of autism in infants
• Menopausal women could 'work out' their hot flashes
• Diabetes reversed in mice using stem cells
• New drug dramatically improves survival in Hodgkin lymphoma patients
• Kids who cook are hungrier for healthy food choices
• A step toward minute factories that produce medicine inside the body
• One step closer to Parkinson's drug
• 'Broken heart syndrome' protects the heart from adrenaline overload
• Significant cardiovascular risk with low carbohydrate-high protein diets, experts warn
• Women with a fear of childbirth endure a longer labor, finds new research
• Half of inhaled soot particles from diesel exhaust, fires gets stuck in the lungs
• How much would our health benefit from leaving the car at home?
• Progress in quest to reduce use of radiation in treatment of pediatric Hodgkin lymphoma
• Post-anesthesia dementia, like Alzheimer's, looks micro-'tubular'
• Alzheimer's spread through the brain mapped: Infects from neuron to neuron
• New mouse model helps explain gene discovery in congenital heart disease

New compound holds promise for treating Duchenne MD, other inherited diseases Posted: 27 Jun 2012 12:42 PM PDT Scientistshave identified a new compound that could treat certain types of genetic disorders in muscles. It is a first, big step in what they hope will lead to human clinical trials for Duchenne Muscular Dystrophy (DMD).

Successful transplant of patient-derived stem cells into mice with muscular dystrophy Posted: 27 Jun 2012 11:25 AM PDT Stem cells from patients with a rare form of muscular dystrophy have been successfully transplanted into mice affected by the same form of dystrophy, according to a new study.

Injecting life-saving oxygen into a vein Posted: 27 Jun 2012 11:25 AM PDT Patients unable to breathe because of acute lung failure or an obstructed airway need another way to get oxygen to their blood -- and fast -- to avoid cardiac arrest and brain injury. Medical researchers have designed tiny, gas-filled microparticles that can be injected directly into the bloodstream to quickly oxygenate the blood.

New vaccine for nicotine addiction Posted: 27 Jun 2012 11:24 AM PDT Researchers have developed and successfully tested in mice an innovative vaccine to treat nicotine addiction. A single dose of their novel vaccine protects mice, over their lifetime, against nicotine addiction. The vaccine is designed to use the animal's liver as a factory to continuously produce antibodies that gobble up nicotine the moment it enters the bloodstream, preventing the chemical from reaching the brain and even the heart.

Researchers delve into airborne particulates Posted: 27 Jun 2012 10:21 AM PDT Scientists have peered into the makeup of complex airborne particulate matter so small that it can be transported into human lungs -- usually without a trace.

Regulation of telomerase in stem cells and cancer cells Posted: 27 Jun 2012 10:21 AM PDT Scientists have gained important insights for stem cell research which are also applicable to human tumors and could lead to the development of new treatments.

Immune response to heart attack worsens atherosclerosis, increases future risk Posted: 27 Jun 2012 10:20 AM PDT A heart attack doesn't just damage heart muscle tissue by cutting off its blood supply, it also sets off an inflammatory cascade that worsens underlying atherosclerosis, actively increasing the risk for a future heart attack. These findings suggest an important new therapeutic strategy for preventing heart attacks and strokes, both of which are caused when atherosclerotic plaques rupture and block important blood vessels.

Scientists measure soot particles in flight Posted: 27 Jun 2012 10:20 AM PDT For the first time, air-polluting soot particles have been imaged in flight down to nanometer resolution. Pioneering a new technique scientists snapped the most detailed images yet of airborne aerosols.

Easier way to make new drug compounds Posted: 27 Jun 2012 10:19 AM PDT Scientists have developed a powerful new technique for manipulating the building-block molecules of organic chemistry. The technique enables chemists to add new functional molecules to previously hard-to-reach positions on existing compounds—making it easier for them to generate new drugs and other organic chemicals.

Parkinson’s disease gene identified with help of Saskatchewan Mennonite families Posted: 27 Jun 2012 10:19 AM PDT Scientists, with the help of Saskatchewan Mennonite families, have identified an abnormal gene which leads to Parkinson's disease.

Brain scans detect early signs of autism in infants Posted: 27 Jun 2012 09:22 AM PDT A new study shows significant differences in brain development in high-risk infants who develop autism starting as early as six months of age.

Menopausal women could 'work out' their hot flashes Posted: 27 Jun 2012 09:22 AM PDT Menopausal women who exercise may experience fewer hot flashes in the 24 hours following physical activity, according to health researchers.

Diabetes reversed in mice using stem cells Posted: 27 Jun 2012 09:22 AM PDT Scientists have reversed diabetes in mice using stem cells. Scientists have shown that human stem cell transplants can successfully restore insulin production and reverse diabetes in mice. Crucially, they re-created the "feedback loop" that enables insulin levels to automatically rise or fall based on blood glucose levels.

New drug dramatically improves survival in Hodgkin lymphoma patients Posted: 27 Jun 2012 09:20 AM PDT A new cancer drug with remarkably few side effects is dramatically improving survival in Hodgkin lymphoma patients who fail other treatments and are nearly out of options.

Kids who cook are hungrier for healthy food choices Posted: 27 Jun 2012 07:33 AM PDT Children who help cook at home are more likely to enjoy fruits and veggies than kids who don't cook, according to a new study.

A step toward minute factories that produce medicine inside the body Posted: 27 Jun 2012 07:33 AM PDT Scientists are reporting an advance toward treating disease with minute capsules containing not drugs -- but the DNA and other biological machinery for making the drug. They describe engineering micro- and nano-sized capsules that contain the genetically coded instructions, plus the read-out gear and assembly line for protein synthesis that can be switched on with an external signal.

One step closer to Parkinson's drug Posted: 27 Jun 2012 07:33 AM PDT A new study details how Parkinson's disease spreads through the brain. Experiments in rat models uncover a process previously used to explain mad cow disease, in which misfolded proteins travel from sick to healthy cells. This model has never before been identified so clearly in a living organism, and the breakthrough brings researchers one step closer to a disease-modifying drug for Parkinson's.

'Broken heart syndrome' protects the heart from adrenaline overload Posted: 27 Jun 2012 07:33 AM PDT A condition that temporarily causes heart failure in people who experience severe stress might actually protect the heart from very high levels of adrenaline, according to a new study.

Significant cardiovascular risk with low carbohydrate-high protein diets, experts warn Posted: 27 Jun 2012 06:22 AM PDT Women who regularly eat a low-carbohydrate, high-protein diet are at greater risk of cardiovascular disease (such as heart disease and stroke) than those who do not, a new study suggests.

Women with a fear of childbirth endure a longer labor, finds new research Posted: 27 Jun 2012 06:22 AM PDT Women who have a fear of childbirth spend longer in labor than women who have no such fear, suggests new research.

Half of inhaled soot particles from diesel exhaust, fires gets stuck in the lungs Posted: 27 Jun 2012 06:20 AM PDT The exhaust from diesel-fueled vehicles, wood fires and coal-driven power stations contains small particles of soot that flow out into the atmosphere. The soot is a scourge for the climate but also for human health. Now for the first time, researchers have studied in detail how diesel soot gets stuck in the lungs. The results show that more than half of all inhaled soot particles remain in the body.

How much would our health benefit from leaving the car at home? Posted: 27 Jun 2012 06:17 AM PDT Walking to get around is considered a moderate physical activity and meets WHO exercise recommendations. A new study confirms that doing short journeys on foot rather than taking the car or motorbike would avoid the death of 108 men and 79 women a year in Catalonia alone. This would imply annual savings of more than 200 million euros.

Progress in quest to reduce use of radiation in treatment of pediatric Hodgkin lymphoma Posted: 27 Jun 2012 06:17 AM PDT A multicenter trial showed that nearly half of young patients with early-stage Hodgkin lymphoma can be cured without undergoing either irradiation or intensive chemotherapy that would leave them at risk for second cancers, infertility, heart and other problems later.

Post-anesthesia dementia, like Alzheimer's, looks micro-'tubular' Posted: 27 Jun 2012 06:16 AM PDT Modern anesthesia is extremely safe. But as risks to heart, lungs and other organs have waned, another problem has emerged in the elderly: post-operative cognitive dysfunction. Mentally, some patients "just aren't the same" for months or longer after surgery. Other factors play a role, but a small number of patients deteriorate mentally due to anesthesia per se. Those with Alzheimer's disease suffer exacerbations, and those without the diagnosis may have it unmasked by anesthesia, suggesting some relationship.

Alzheimer's spread through the brain mapped: Infects from neuron to neuron Posted: 26 Jun 2012 02:27 PM PDT The inexorable spread of Alzheimer's disease through the brain leaves dead neurons and forgotten thoughts in its wake. Researchers have now shown how toxic proteins are transferred from neuron to neuron.

New mouse model helps explain gene discovery in congenital heart disease Posted: 26 Jun 2012 01:38 PM PDT Scientists now have clues to how a gene mutation discovered in families affected with congenital heart disease leads to underdevelopment of the walls that separate the heart into four chambers. A new study suggests that abnormal development of heart cells during embryogenesis may be to blame.

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