ScienceDaily: Health & Medicine News

---

• Scan then surgery: Best route to trauma management?
• Watching the production of new proteins in live cells
• Not guility: Parkinson and protein phosphorylation
• Disabling enzyme reduces tumor growth, cripples cancer cells, finds new study
• Thyroid cancer biopsy guidelines should be simplified, researchers say
• New implanted defibrillator works well without touching heart
• Even mild stress can make it difficult to control your emotions
• Touch and movement neurons shape the brain's internal image of the body
• Immune system, skin microbiome 'complement' one another
• Breakthrough in DNA editing technology
• Interpretation of do-not-resuscitate order appears to vary among pediatric physicians
• Extremely preterm infants and risk of developing neurodevelopmental impairment later in childhood
• Terminology used to describe preinvasive breast cancer may affect patients' treatment preferences
• Intervention appears effective to prevent weight gain among disadvantaged women
• Comprehensive Parkinson's biomarker test has prognostic and diagnostic value
• Oxygen-generating compound shows promise for saving tissue after severe injury
• New, 'robust' treatment for stroke uses genetic material from bone marrow
• Researchers develop software tool for cancer genomics
• RNA double helix structure identified using synchrotron light
• Four or more cups of coffee a day may keep prostate cancer recurrence and progression away
• New minimally invasive technique for melanoma
• New approach to remedying childhood visual disorders
• Skin cell defect is surprising allergy trigger: Skin and food allergies can be result of skin cell 'glue' deficiency
• Development of a therapeutic algorithm for optimal nosebleed management
• Patients leaving hospital against medical advice more likely to be readmitted or die
• Midwest air quality alert may mean first sick day for kids heading back to school
• Women at increasing risk of kidney stones, related ER visits
• New function for a well-known immune messenger molecule
• Worldwide ban on flame retardant
• Through four years' training, college football players gain strength and size
• Sweaty palms and racing heart may benefit some negotiators
• Pediatric readmission rates aren't indicator of hospital performance, study shows
• Healthcare professionals need to look out for fabricated illness in children
• 'Shapeshifting' computer program will open up drug discovery for tricky disease targets
• A skeleton for chromosomes
• Antisense oligoneucleotide corrects striatal transcriptional abnormalities and protects function in Huntington's disease mice
• New study supports intracerebral injections of bone marrow-derived stem cells to prevent or reduce post-stroke cognitive deficits
• New screening strategy may catch ovarian cancer at early stages
• Researchers uncover new biological target for combating Parkinson's disease
• Biphasic electrical stimulation: A strategy may bring hope to spinal cord injury patients
• BT-R3 mediates killing of the malaria vector Anopheles gambiae by Bacillus thuringiensis
• Nitric oxide can regulate gene expression
• UCLA researchers invent portable device for common kidney tests

Scan then surgery: Best route to trauma management? Posted: 26 Aug 2013 06:56 PM PDT Giving severe trauma victims a computed tomography (CT) scan before managing their bleeding could boost their chances of survival, suggests a new study. The findings are at odds with current guidelines, and so contribute to the on-going debate about how best to treat patients with severe trauma injuries. Trauma is the leading cause of death in young adults in many countries.

Watching the production of new proteins in live cells Posted: 26 Aug 2013 03:31 PM PDT Researchers have made a significant step in understanding and imaging protein synthesis, pinpointing exactly where and when cells produce new proteins. They have developed a new technique to produce high-resolution imaging of newly synthesized proteins inside living cells.

Not guility: Parkinson and protein phosphorylation Posted: 26 Aug 2013 03:29 PM PDT Clues left at the scene of the crime don't always point to the guilty party, as researchers investigating Parkinson's disease have discovered. It is generally accepted that the disease is aggravated when a specific protein is phosohorylated -- that is to say chemically transformed -- by an enzyme. Now neuroscientists have been able to show that, on the contrary, this transformation tends to protect against the progression of the disease. This conclusion could change therapeutic approaches currently being developed by pharmas.

Disabling enzyme reduces tumor growth, cripples cancer cells, finds new study Posted: 26 Aug 2013 03:28 PM PDT Researchers have found that knocking out an enzyme needed to make lipids can dramatically cripple the ability of aggressive cancer cells to spread and grow tumors. The discovery points to a promising new target for treatment of aggressive cancers.

Thyroid cancer biopsy guidelines should be simplified, researchers say Posted: 26 Aug 2013 03:28 PM PDT Researchers have called for simplified guidelines on when to biopsy thyroid nodules for cancer, which they say would result in fewer unnecessary biopsies.

New implanted defibrillator works well without touching heart Posted: 26 Aug 2013 03:26 PM PDT A new type of defibrillator implanted under the skin can detect dangerously abnormal heart rhythms and deliver shocks to restore a normal heartbeat without wires touching the heart, according to new research.

Even mild stress can make it difficult to control your emotions Posted: 26 Aug 2013 03:05 PM PDT Even mild stress can thwart therapeutic measures to control emotions, a team of neuroscientists has found. Their findings point to the limits of clinical techniques while also shedding new light on the barriers that must be overcome in addressing afflictions such as fear or anxiety.

Touch and movement neurons shape the brain's internal image of the body Posted: 26 Aug 2013 03:05 PM PDT The brain's tactile and motor neurons, which perceive touch and control movement, may also respond to visual cues, according to researchers.

Immune system, skin microbiome 'complement' one another Posted: 26 Aug 2013 03:05 PM PDT Researchers demonstrate for the first time that the immune system influences the skin microbiome. A new study found that the skin microbiome -- a collection of microorganisms inhabiting the human body -- is governed, at least in part, by an ancient branch of the immune system called complement.

Breakthrough in DNA editing technology Posted: 26 Aug 2013 03:05 PM PDT Scientists have found a way to apply a powerful new DNA-editing technology more broadly than ever before.

Interpretation of do-not-resuscitate order appears to vary among pediatric physicians Posted: 26 Aug 2013 03:02 PM PDT Clinicians use the do-not-resuscitate (DNR) order not only as a guide for therapeutic decisions during a cardiopulmonary arrest but also as a surrogate for broader treatment directives, according to a new study.

Extremely preterm infants and risk of developing neurodevelopmental impairment later in childhood Posted: 26 Aug 2013 03:02 PM PDT A meta-analysis of previously reported studies examined the rate of moderate to severe and severe neurodevelopmental impairment by gestational age in extremely preterm survivors followed up between ages 4 and 8 years, and determined whether there is a significant difference in impairment rates between the successive weeks of gestation of survivors.

Terminology used to describe preinvasive breast cancer may affect patients' treatment preferences Posted: 26 Aug 2013 03:02 PM PDT When ductal carcinoma in situ (DCIS, a preinvasive malignancy of the breast) is described as a high-risk condition rather than cancer, more women report that they would opt for nonsurgical treatments.

Intervention appears effective to prevent weight gain among disadvantaged women Posted: 26 Aug 2013 03:02 PM PDT An intervention not focused on weight loss was effective for weight gain prevention among socioeconomically disadvantaged black women, according to a new report.

Comprehensive Parkinson's biomarker test has prognostic and diagnostic value Posted: 26 Aug 2013 03:02 PM PDT Researchers report the first biomarker results reported from the Parkinson's Progression Markers Initiative (PPMI), showing that a comprehensive test of protein biomarkers in spinal fluid have prognostic and diagnostic value in early stages of Parkinson's disease.

Oxygen-generating compound shows promise for saving tissue after severe injury Posted: 26 Aug 2013 03:02 PM PDT The same compound in a common household clothes detergent shows promise as a treatment to preserve muscle tissue after severe injury. Researchers hope the oxygen-generating compound could one day aid in saving and repairing limbs and tissue.

New, 'robust' treatment for stroke uses genetic material from bone marrow Posted: 26 Aug 2013 11:38 AM PDT In the latest in a series of experiments testing the use of stem cells to treat neurological disease, researchers have shown for the first time that microscopic material in the cells offers a "robust" treatment for crippling stroke.

Researchers develop software tool for cancer genomics Posted: 26 Aug 2013 11:37 AM PDT Researchers have developed a new bioinformatics software tool designed to more easily identify genetic mutations responsible for cancers.

RNA double helix structure identified using synchrotron light Posted: 26 Aug 2013 11:36 AM PDT Scientists successfully crystallized a short RNA sequence, poly (rA)11, and confirmed the hypothesis of a poly (rA) double-helix.

Four or more cups of coffee a day may keep prostate cancer recurrence and progression away Posted: 26 Aug 2013 11:36 AM PDT Coffee consumption is associated with a lower risk of prostate cancer recurrence and progression, according to a new study.

New minimally invasive technique for melanoma Posted: 26 Aug 2013 09:31 AM PDT Surgical oncologists are now using laparoscopic procedure to remove lymph nodes, cutting chance of infection and reducing recovery time in half.

New approach to remedying childhood visual disorders Posted: 26 Aug 2013 09:31 AM PDT By discovering the role of key neurons that mediate an important part of vision development, neurobiologists have revealed a new approach to correcting visual disorders in children who suffer from early cataracts or amblyopia, also known as lazy eye.

Skin cell defect is surprising allergy trigger: Skin and food allergies can be result of skin cell 'glue' deficiency Posted: 26 Aug 2013 09:31 AM PDT A structural defect in skin cells can contribute to allergy development, including skin and food allergies, traditionally thought primarily to be a dysfunction of the immune system.

Development of a therapeutic algorithm for optimal nosebleed management Posted: 26 Aug 2013 09:31 AM PDT Approximately 60 percent of people experience epistaxis, commonly known as nosebleed, at least once in their lifetime. Of those who experience nosebleed, six percent require medical treatment. A new study explores which nosebleed treatment options demonstrate the best outcomes.

Patients leaving hospital against medical advice more likely to be readmitted or die Posted: 26 Aug 2013 09:31 AM PDT People who leave hospital against their doctors' orders are more likely to be readmitted to hospital or die, according to a new study.

Midwest air quality alert may mean first sick day for kids heading back to school Posted: 26 Aug 2013 09:30 AM PDT The Midwest is experiencing dangerous levels of mold in the air as the first dangerous air alert is called for the 2013 allergy reporting season. Gottlieb Allergy Count, the official allergy count for the Midwest, reports the mold count today is 53,000, a high for 2013, and well over the 50,000 threshold that signals a dangerous air quality warning.

Women at increasing risk of kidney stones, related ER visits Posted: 26 Aug 2013 08:33 AM PDT The risk of women developing kidney stones is rising, as is the number of cases being seen in US emergency departments, while the rate of hospitalization for the disorder has remained stable.

New function for a well-known immune messenger molecule Posted: 26 Aug 2013 08:33 AM PDT Scientists have discovered a new function of the well-known messenger protein interleukin-7: It facilitates the drainage of lymph fluid from tissues. In the future, the scientists plan to investigate whether this molecule could be used to prevent or treat lymphedema.

Worldwide ban on flame retardant Posted: 26 Aug 2013 07:57 AM PDT The flame retardant HBCD may no longer be produced or used. This was decided by representatives from over 160 countries in late May at a UN conference on chemicals in Geneva. HBCD was formerly used as a flame retardant for plastics, electronics and textiles, and especially for insulation panels in buildings.

Through four years' training, college football players gain strength and size Posted: 26 Aug 2013 07:52 AM PDT From freshman through senior year, college football players achieve significant increases in strength and size, reports a study.

Sweaty palms and racing heart may benefit some negotiators Posted: 26 Aug 2013 07:00 AM PDT The idea of having to negotiate over the price of a new car sends many into the cold sweats, but new research suggests that sweaty palms and a racing heart may actually help some people in getting a good deal.

Pediatric readmission rates aren't indicator of hospital performance, study shows Posted: 26 Aug 2013 07:00 AM PDT Readmission rates of adult patients to the same hospital within 30 days are an area of national focus and a potential indicator of clinical failure and unnecessary expenditures. However, a new study shows that hospital readmissions rates for children are not necessarily meaningful measures of the quality of their care.

Healthcare professionals need to look out for fabricated illness in children Posted: 26 Aug 2013 07:00 AM PDT While it's rare for a parent to fabricate an illness in their child, a researcher says physicians and other health professionals need to be on the alert for this form of child abuse.

'Shapeshifting' computer program will open up drug discovery for tricky disease targets Posted: 26 Aug 2013 06:58 AM PDT Combination of technologies could reduce the number of early trial compounds from millions to hundreds, potentially shaving years off the discovery-development program.

A skeleton for chromosomes Posted: 26 Aug 2013 06:58 AM PDT Scientists have found that the structure of chromosomes is supported by a kind of molecular skeleton, made of cohesin.

Antisense oligoneucleotide corrects striatal transcriptional abnormalities and protects function in Huntington's disease mice Posted: 26 Aug 2013 06:58 AM PDT Findings from postmortem studies of the brains of Huntington's Disease (HD) patients suggest that transcriptional dysregulation may be an early step in the pathogenesis of HD before symptoms appear. Other studies report transcriptional alterations in the brains of some mouse models of HD. A new study has found transcriptional changes in mouse striatum which correlate with progressive motor and psychiatric deficits and, most importantly, reports for the first time, that an antisense oligonucleotide (ASO) may be used therapeutically to both correct striatal transcriptional abnormalities and improve motor and behavioral problems.

New study supports intracerebral injections of bone marrow-derived stem cells to prevent or reduce post-stroke cognitive deficits Posted: 26 Aug 2013 06:58 AM PDT Cognitive deficits following ischemic stroke are common and debilitating, even in the relatively few patients who are treated expeditiously so that clots are removed or dissolved rapidly and cerebral blood flow restored. A new study demonstrates that intracerebral injection of bone-marrow-derived mesenchymal stem cells (BSCs) reduces cognitive deficits produced by temporary occlusion of cerebral blood vessels in a rat model of stroke, suggesting that BSCs may offer a new approach for reducing post-stroke cognitive dysfunction.

New screening strategy may catch ovarian cancer at early stages Posted: 26 Aug 2013 06:58 AM PDT A new screening strategy for ovarian cancer appears to be highly specific for detecting the disease before it becomes lethal. If verified in an ongoing clinical trial, it could potentially help save the lives of thousands of women each year in the United States alone. There currently are no established screening strategies for ovarian cancer. The disease often causes no specific symptoms and is difficult to detect in the early stages when it is most responsive to treatment. Therefore, ovarian cancer is highly lethal because most women have advanced disease when they are diagnosed.

Researchers uncover new biological target for combating Parkinson's disease Posted: 25 Aug 2013 02:15 PM PDT Researchers have brought new clarity to the picture of what goes awry in the brain during Parkinson's disease and identified a compound that eases the disease's symptoms in mice. Their discoveries also overturn established ideas about the role of a protein considered key to the disease's progress.

Biphasic electrical stimulation: A strategy may bring hope to spinal cord injury patients Posted: 24 Aug 2013 10:16 AM PDT Transplantation stem cells is a potential clinical therapy for repair of spinal cord injury. However, transplanted cells are especially vulnerable due to a lack of sufficient growth factors at the transplant site. A new study demonstrates that biphasic electrical stimulation (BES) prevents growth factor-deprived apoptosis through the BDNF-PI3K/Akt signaling in neural stem cells. The findings may guide future efforts to stem cell-based transplantation therapy. It also raises hope that BES may one day be used to restore spinal cord injury.

BT-R3 mediates killing of the malaria vector Anopheles gambiae by Bacillus thuringiensis Posted: 24 Aug 2013 10:16 AM PDT The cadherin receptor, BT-R3, of Anopheles gambiae reported in a new study mediates the killing action of the Cry4B mosquitocidal toxin. Characterization of the toxin-receptor complex will facilitate protein design for creation of new customized mosquitocidal proteins and peptide mimics that might be more effective than the natural toxins themselves and less able to bring about insect host resistance.

Nitric oxide can regulate gene expression Posted: 24 Aug 2013 10:14 AM PDT Scientists have discovered a new role for nitric oxide, a gas molecule crucial for cellular signaling and health. Researchers found that nitric oxide plays an important role in epigenetics -- heritable alterations in gene expression caused by mechanisms other than changes in DNA sequence.

UCLA researchers invent portable device for common kidney tests Posted: 23 Aug 2013 06:13 AM PDT A lightweight and portable device conducts kidney tests and transmits data through a cellphone attachment may significantly reduce the need for frequent office visits by diabetes patients and others with chronic kidney ailments. This device, can determine levels of albumin -- a protein commonly found in blood that is a sign of danger when found in urine -- and transmit the results within seconds.

You are subscribed to email updates from ScienceDaily: Health & Medicine News To stop receiving these emails, you may unsubscribe now.	Email delivery powered by Google
Google Inc., 20 West Kinzie, Chicago IL USA 60610