ScienceDaily: Health & Medicine News

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• Brief exposure to performance-enhancing drugs may be permanently 'remembered' by muscles
• Eleven new genetic susceptibility factors for Alzheimer's disease discovered through the largest study
• Cell nucleus protein in brown fat cells governs daily control of body temperature
• Scientists eye longer-term forecasts of U. S. heat waves
• Novel mutations define two types of bone tumor: Two related genes underlie the development of two rare bone tumors in nearly 100 per cent of patients
• After a concussion, students may need gradual transition back to academics
• New oral treatment shows significant promise in the treatment of mouth and genital ulcers in people with Behcet's syndrome
• Recent advances in medicine lead to better health for children with juvenile arthritis
• New tools in juvenile arthritis treatment help children, their families and their rheumatologists share in important health care decision making
• Common rheumatoid arthritis treatment may be effective in treating immunoglobulin G4-related disease
• Children whose mothers have lupus might be at increased risk of autism spectrum disorders
• Few children and young adults with autoimmune diseases are receiving the HPV vaccination
• Smoking can increase x-ray damage in people with ankylosing spondylitis by as much as five times
• Medication used to control blood sugar in people with type 2 diabetes may also reduce the risk of autoimmune diseases
• Stroke prevention surgery less effective than meds, lifestyle change
• Only 11 percent of children involved in bike accidents wear a helmet
• Pediatric musculoskeletal MRSA infections on the rise
• How bacteria with a sweet tooth may keep us healthy
• Enzyme restores function with diabetic kidney disease
• Positive personal growth following breast cancer diagnosis
• Multiple, distinct Y chromosomes associated with significant excess risk of prostate cancer
• Researchers identify molecule that could aid lung cancer detection, treatment
• Supplement cuts muscle loss in knee replacements
• New ALS drug headed for phase II trial
• Measuring blood sugar with light
• Next-gen sequencing identifies genes associated with speech disorder
• Study reveals first effective medicine to treat cocaine dependence
• Salvianolate for treatment of cerebral ischemia-reperfusion injuries

Brief exposure to performance-enhancing drugs may be permanently 'remembered' by muscles Posted: 27 Oct 2013 05:56 PM PDT Brief exposure to anabolic steroids may have long lasting, possibly permanent, performance-enhancing effects, shows a new study.

Eleven new genetic susceptibility factors for Alzheimer's disease discovered through the largest study Posted: 27 Oct 2013 03:53 PM PDT The largest international study ever conducted on Alzheimer's disease (AD), the I-GAP (International Genomics Alzheimer's Project) consortium has identified 11 new regions of the genome involved in the onset of this neurodegenerative disease. This study gives an overview of the molecular mechanisms underlying the disease, opening up to a better understanding of the pathophysiology of AD.

Cell nucleus protein in brown fat cells governs daily control of body temperature Posted: 27 Oct 2013 03:50 PM PDT Body temperature follows a 24-hour rhythm, peaking during the day, low at night. The benefit might be the conservation of energy while sleeping. It is also critical to be able to adapt to changes in ambient temperature regardless of the time of day. A new mouse study shows how body temperature rhythms are synchronized while maintaining the ability to adapt to changes in environmental temperature day or night.

Scientists eye longer-term forecasts of U. S. heat waves Posted: 27 Oct 2013 03:50 PM PDT Scientists have fingerprinted a distinctive atmospheric wave pattern high above the Northern Hemisphere that can foreshadow the emergence of summertime heat waves in the United States more than two weeks in advance. The new research could potentially enable forecasts of the likelihood of U.S. heat waves 15-20 days out, giving society more time to prepare for these often-deadly events.

Novel mutations define two types of bone tumor: Two related genes underlie the development of two rare bone tumors in nearly 100 per cent of patients Posted: 27 Oct 2013 11:06 AM PDT Scientists have made a rare discovery that allows them to attribute two types of tumour almost entirely to specific mutations that lie in two related genes.

After a concussion, students may need gradual transition back to academics Posted: 27 Oct 2013 09:35 AM PDT A concussion should not only take a student athlete off the playing field -- it may also require a break from the classroom, according to a new clinical report.

New oral treatment shows significant promise in the treatment of mouth and genital ulcers in people with Behcet's syndrome Posted: 27 Oct 2013 09:31 AM PDT Apremilast, an orally available small molecule modulating several inflammatory pathways, which is pending approval by the United States Food and Drug Administration, is showing promise in the treatment of mouth and genital ulcers in people with Behcet's syndrome, according to new research.

Recent advances in medicine lead to better health for children with juvenile arthritis Posted: 27 Oct 2013 09:31 AM PDT There has been a progressive decline in the levels of disease activity and disability among children with juvenile idiopathic arthritis over the past 25 years, according to new research. This research confirms the notion that recent advances in the management of the disease have led to a substantial improvement in health outcomes for children living with it.

New tools in juvenile arthritis treatment help children, their families and their rheumatologists share in important health care decision making Posted: 27 Oct 2013 09:31 AM PDT Learning that your child has arthritis can lead to a number of questions and concerns about treatment options and prognosis. But, partnering with your child and his or her rheumatologist in shared decision making about their health care can lead to better outcomes overall, according to new research.

Common rheumatoid arthritis treatment may be effective in treating immunoglobulin G4-related disease Posted: 27 Oct 2013 09:31 AM PDT Rituximab (Rituxan®) — a drug commonly used rheumatoid arthritis, granulomatosis with polyangiitis (formerly Wegener's), and certain types of cancers — may be a safe and effective treatment for immunoglobulin G4-related disease (commonly called IgG4-RD), according to new research.

Children whose mothers have lupus might be at increased risk of autism spectrum disorders Posted: 27 Oct 2013 09:31 AM PDT Children born to mothers with lupus may be at twice the risk of autism spectrum disorders than those born to mothers without the disease.

Few children and young adults with autoimmune diseases are receiving the HPV vaccination Posted: 27 Oct 2013 09:29 AM PDT The number of children and young adults with autoimmune diseases receiving the HPV vaccination is profoundly low despite studies showing the vaccine to be safe and effective, according to new research. Given the increased incidence of HPV in people with autoimmune diseases, this research suggests that increased public health efforts are needed.

Smoking can increase x-ray damage in people with ankylosing spondylitis by as much as five times Posted: 27 Oct 2013 09:29 AM PDT Smoking can increase the effect of inflammation on X-ray damage in people with ankylosing spondylitis by as much as five times. And, the increase is as much as 13 times higher in men with the disease who smoke than women who don't smoke, according to new research.

Medication used to control blood sugar in people with type 2 diabetes may also reduce the risk of autoimmune diseases Posted: 27 Oct 2013 09:29 AM PDT Dipeptidyl peptidase-4 inhibitors commonly used to control blood sugar levels in people with type 2 diabetes may also reduce the risk of autoimmune diseases in these patients, according to new research.

Stroke prevention surgery less effective than meds, lifestyle change Posted: 26 Oct 2013 01:49 PM PDT The final results of a stroke prevention study in patients with narrowed brain arteries confirm earlier findings: Medication plus lifestyle changes are safer and more effective at preventing stroke than a surgical technique called stenting.

Only 11 percent of children involved in bike accidents wear a helmet Posted: 26 Oct 2013 06:11 AM PDT Despite a California bike helmet mandate, only 11 percent of Los Angeles County children treated for bike-related injuries were wearing a helmet, according to new research.

Pediatric musculoskeletal MRSA infections on the rise Posted: 26 Oct 2013 06:11 AM PDT Pediatric musculoskeletal Staphylococcus aureus bacterial infections have been evolving over the past decade, with more children diagnosed with the more virulent, methicillin-resistant Staphylococcus aureus (MRSA) today than 10 years ago. The result is longer hospitals stays, more surgeries and other related complications, according to new research.

How bacteria with a sweet tooth may keep us healthy Posted: 25 Oct 2013 03:57 PM PDT Some gut bacterial strains are specifically adapted to use sugars in our gut lining to aid colonisation, potentially giving them a major influence over our gut health.

Enzyme restores function with diabetic kidney disease Posted: 25 Oct 2013 03:56 PM PDT Researchers say that, while a prevailing theory suggests elevated cellular levels of glucose ultimately result in diabetic kidney disease, the truth may, in fact, be quite the opposite. The findings could fundamentally change understanding of how diabetes-related diseases develop – and how they might be better treated.

Positive personal growth following breast cancer diagnosis Posted: 25 Oct 2013 12:52 PM PDT Although being diagnosed with breast cancer is usually an extremely stressful experience for most women, a new study by researchers has found that there also can be unexpected benefits.

Multiple, distinct Y chromosomes associated with significant excess risk of prostate cancer Posted: 25 Oct 2013 11:32 AM PDT Multiple, distinct Y chromosomes are associated with significant excess prostate cancer risk, according to analysis of multi-generational families. Researchers intend to study these Y chromosomes for genetic mutations that predispose a man to develop the cancer.

Researchers identify molecule that could aid lung cancer detection, treatment Posted: 25 Oct 2013 10:53 AM PDT Researchers have discovered a molecule that could help lead to the non-invasive detection of lung cancer as well as its treatment.

Supplement cuts muscle loss in knee replacements Posted: 25 Oct 2013 10:53 AM PDT Twenty grams of essential amino acids taken twice daily for a week before and for two weeks after knee-replacement surgeries helped 16 patients, mean age 69, recover faster and with much less muscle atrophy than a control group ingesting a placebo.

New ALS drug headed for phase II trial Posted: 25 Oct 2013 10:52 AM PDT Researchers will soon begin phase IIa clinical trials of TDI-132, a drug that in animal models has shown promise in reducing the inflammation associated with Amyotrophic Lateral Sclerosis.

Measuring blood sugar with light Posted: 25 Oct 2013 09:30 AM PDT One key to healthful living with diabetes is monitoring sugar levels to ensure they remain stable. People can easily do this at home using devices that read sugar levels in a drop of blood. Now a team of researchers has devised a non-invasive way to make monitoring easier. Using infrared laser light applied on top of the skin, they measure sugar levels in the fluid in and under skin cells to read blood sugar levels.

Next-gen sequencing identifies genes associated with speech disorder Posted: 25 Oct 2013 08:39 AM PDT A collaborative team of researchers has used next generation sequencing to identify clinically relevant genetic variants associated with a rare pediatric speech disorder.

Study reveals first effective medicine to treat cocaine dependence Posted: 25 Oct 2013 08:37 AM PDT New research reveals that topiramate, a drug approved by the U.S. Food and Drug Administration to treat epilepsy and migraine headaches also could be the first reliable medication to help treat cocaine dependence.

Salvianolate for treatment of cerebral ischemia-reperfusion injuries Posted: 25 Oct 2013 07:24 AM PDT Salvianolic acid B, also called salvia magnesium acetate, exerts strong resistance to oxidative stress and inflammatory reaction, and improves energy metabolism against cerebral ischemia-reperfusion injuries. Researchers have found that administration of salvianolate during reperfusion after ischemia appears to attenuate brain tissue damage and inhibit neuronal apoptosis by increasing heat shock protein 22 and phosphorylated protein kinase B expression.

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