ScienceDaily: Health & Medicine News

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• Counting the cost of infertility treatment
• Study finds parental stress linked to obesity in children
• Enzalutamide in prostate cancer: Hints of added benefit
• Scientists discover novel hormone essential for heart development
• Surprising discovery: Skin communicates with liver
• Promising results for Swedish cancer drug candidate
• Study delivers protein across blood-brain barrier to degrade Alzheimer's plaques
• Human stem cells predict efficacy of Alzheimer drugs
• Trucks a significant cause of severe accidents, study finds
• Predictor of prostate cancer outcomes identified
• Drug induces morphologic, molecular, clinical remissions in myelofibrosis
• Scientists accelerate aging in stem cells to study age-related diseases like Parkinson's
• Researchers uncover why combination drug treatment ineffective in cancer clinical trials
• Liver transplant survival rates lower in black than white pediatric patients
• Traumatic brain injury rehab outcomes studied
• Activating pathway could restart hair growth in dormant hair follicles
• Criteria shows one year death risk at time of hospital admission
• Cancer mutation likely trigger of scleroderma
• Emerging bird flu strain poorly adapted for infecting humans
• Brain cancer cells hide while drugs seek
• Nurse-led innovations demonstrate improved patient outcomes, bottom-line impact
• More alcohol, traffic laws mean fewer traffic deaths
• Alcohol in pregnancy causes children to have impaired social skills
• High-tech athletic shoe for pure running pleasure
• Blacks happier at work than whites despite fewer friends, less autonomy
• Teen sleep problems: Social ties more important than biology
• Almost 600 under-16s take up smoking every day in UK
• Scientists present groundbreaking HIV prevention research
• Protein that helps developing germ cells wipe genes clean of past imprints
• Successful repair of bone defects using novel tissue engineered bone graft

Counting the cost of infertility treatment Posted: 06 Dec 2013 09:43 AM PST From drug therapy to IVF, out-of pocket costs can range from $900 to $19,000 per treatment cycle, report researchers.

Study finds parental stress linked to obesity in children Posted: 06 Dec 2013 08:17 AM PST Parental stress is linked to weight gain in children, according to a new study.

Enzalutamide in prostate cancer: Hints of added benefit Posted: 06 Dec 2013 08:17 AM PST Enzalutamide can prolong survival in certain patients with prostate cancer, and delay occurrence of bone lesions. The new drug also offers advantages with regards to pain.

Scientists discover novel hormone essential for heart development Posted: 06 Dec 2013 07:16 AM PST Scientists have identified a gene encoding a hormone that could potentially be used as a therapeutic molecule to treat heart diseases. The hormone -- which they have chosen to name ELABELA -- is only 32 amino-acids long, making it amongst the tiniest proteins made by the human body.

Surprising discovery: Skin communicates with liver Posted: 06 Dec 2013 07:16 AM PST Researchers have discovered that the skin is capable of communicating with the liver. The discovery has surprised the scientists, and they say that it may help our understanding of how skin diseases can affect the rest of the body.

Promising results for Swedish cancer drug candidate Posted: 06 Dec 2013 07:16 AM PST A new study presents very promising results for the treatment of the cancer form multiple myeloma. The findings are so promising that the scientists are teaming up with Harvard to bring the drug to clinical trials on patients.

Study delivers protein across blood-brain barrier to degrade Alzheimer's plaques Posted: 06 Dec 2013 06:14 AM PST Biologists substantially degraded Alzheimer's plaques in mice brains and human brain tissue by sending a fused protein across the blood-brain barrier. Their technique not only offers a potential strategy for treating the debilitating neurological disease, but also other diseases that affect the brain and eyes.

Human stem cells predict efficacy of Alzheimer drugs Posted: 06 Dec 2013 06:11 AM PST Why do certain Alzheimer medications work in animal models but not in clinical trials in humans? A research team has been able to show that results of established test methods with animal models and cell lines used up until now can hardly be translated to the processes in the human brain. Drug testing should therefore be conducted with human nerve cells, conclude the scientists.

Trucks a significant cause of severe accidents, study finds Posted: 05 Dec 2013 07:00 PM PST Trucks are responsible for 4,500 deaths per year in the United States. Truck crashes also cause huge losses in productivity, property and personal injury. New research just published details how trucks account for 8% of US highway traffic, yet are involved in 11% of fatal road crashes.

Predictor of prostate cancer outcomes identified Posted: 05 Dec 2013 02:18 PM PST Researchers have identified a biomarker for a cellular switch that accurately predicts which prostate cancer patients are likely to have their cancer recur or spread.

Drug induces morphologic, molecular, clinical remissions in myelofibrosis Posted: 05 Dec 2013 01:58 PM PST Imetelstat, a novel telomerase inhibiting drug, has been found to induce morphologic, molecular and clinical remissions in some patients with myelofibrosis a study has found.

Scientists accelerate aging in stem cells to study age-related diseases like Parkinson's Posted: 05 Dec 2013 11:16 AM PST A study has revealed a new method for converting induced pluripotent stem cells (iPSCs) into nerve cells that recapitulate features associated with aging as well as Parkinson's disease. The simple approach, which involves exposing iPSC-derived cells to a protein associated with premature aging called progerin, could enable scientists to use stem cells to model a range of late-onset disorders, opening new avenues for preventing and treating these devastating diseases.

Researchers uncover why combination drug treatment ineffective in cancer clinical trials Posted: 05 Dec 2013 11:16 AM PST Medical researchers have discovered that combination drug therapy didn't work well in clinical trials for cancer patients because one drug was making the other drug ineffective.

Liver transplant survival rates lower in black than white pediatric patients Posted: 05 Dec 2013 11:15 AM PST Novel research reveals racial and socioeconomic disparities among pediatric liver transplant patients. Findings indicate that graft and patient survival was higher in white children than minorities. Studies show that over the last 30 years pediatric patient survival, at one year following liver transplant, is 90% compared to 70% prior to 1980. Experts suggest that as survival rates improve, understanding racial and socioeconomic differences in pediatric populations are important factors to consider.

Traumatic brain injury rehab outcomes studied Posted: 05 Dec 2013 11:14 AM PST For patients recovering from a traumatic brain injury (TBI), the rehabilitation process – compensating for changes in functioning, adaptation and even community reintegration – can be challenging. Unfortunately, not all rehab programs are created equal, and with the differences comes a difference in outcomes, according to a first-of-its-kind study.

Activating pathway could restart hair growth in dormant hair follicles Posted: 05 Dec 2013 11:14 AM PST A new study identifies a molecular pathway that can be activated to prompt hair growth of dormant hair follicles, or blocked to prevent growth of unwanted hair.

Criteria shows one year death risk at time of hospital admission Posted: 05 Dec 2013 11:13 AM PST A new tool allows doctors to recognize patients at highest mortality risk, matching treatments to values and health goals.

Cancer mutation likely trigger of scleroderma Posted: 05 Dec 2013 11:13 AM PST Scientists have found evidence that cancer triggers the autoimmune disease scleroderma, which causes thickening and hardening of the skin and widespread organ damage.

Emerging bird flu strain poorly adapted for infecting humans Posted: 05 Dec 2013 11:13 AM PST Avian influenza virus H7N9, which killed several dozen people in China earlier this year, has not yet acquired the changes needed to infect humans easily, according to a new study by scientists.

Brain cancer cells hide while drugs seek Posted: 05 Dec 2013 11:13 AM PST A team of scientists has found that brain cancer cells resist therapy by dialing down the gene mutation targeted by drugs, then re-amplify that growth-promoting mutation after therapy has stopped.

Nurse-led innovations demonstrate improved patient outcomes, bottom-line impact Posted: 05 Dec 2013 09:35 AM PST Nurse-led initiatives in Indiana measurably improved patient outcomes while demonstrating anticipated financial savings of more than $5.2 million to their organizations, according to initial results from a hospital-based nurse leadership and innovation training program.

More alcohol, traffic laws mean fewer traffic deaths Posted: 05 Dec 2013 09:34 AM PST States with a higher number of alcohol- and traffic-related laws have a lower proportion of traffic deaths than do states with fewer such laws on the books, a study by researchers has found.

Alcohol in pregnancy causes children to have impaired social skills Posted: 05 Dec 2013 06:21 AM PST A recent study has found that drinking alcohol while pregnant means your child is more likely to develop issues with social skills as they grow older.

High-tech athletic shoe for pure running pleasure Posted: 05 Dec 2013 06:20 AM PST Jogging keeps you fit and is healthy. However, athletes that start training can overdo it and easily pull and tear ligaments. A new high-tech running shoe will evaluate running form in real time and thereby counter these injuries in future.

Blacks happier at work than whites despite fewer friends, less autonomy Posted: 05 Dec 2013 06:19 AM PST Despite working in more routine and less autonomous jobs, having fewer close friends at work, and feeling less supported by their coworkers, blacks report significantly more positive emotions in the workplace than whites, according to a new study.

Teen sleep problems: Social ties more important than biology Posted: 05 Dec 2013 06:19 AM PST Medical researchers point to developmental factors, specifically the decline of the sleep-inducing hormone melatonin, as an explanation for why children get less sleep as they become teenagers. But a new study suggests that social ties, including relationships with peers and parents, may be even more responsible for changing sleep patterns among adolescents.

Almost 600 under-16s take up smoking every day in UK Posted: 04 Dec 2013 05:27 PM PST Almost 600 under-16s take up smoking every day in the UK, suggests research published. In London alone, the daily tally is 67 -- more than 2 classrooms-full.

Scientists present groundbreaking HIV prevention research Posted: 04 Dec 2013 03:24 PM PST Researchers are making history by proving that it's possible to develop a drug delivery system that has the potential to protect women from sexually transmitted HIV and herpes simplex virus, while at the same time preventing unintended pregnancy. The report describes in vivo results from a novel, multipurpose pod-intravaginal ring delivering three antiretroviral drugs in combination with two hormonal contraceptives.

Protein that helps developing germ cells wipe genes clean of past imprints Posted: 04 Dec 2013 03:22 PM PST A protein called Tet1 is partly responsible for giving primordial germ cells a clean epigenetic slate before developing into sperm and egg cells, according to a new study. This discovery could help provide clues to the cause of some kinds of neonatal growth defects and may also help advance the development of stem cell models of disease.

Successful repair of bone defects using novel tissue engineered bone graft Posted: 04 Dec 2013 03:22 PM PST In this study, scientists engineered a novel biomimetic tissue engineered bone graft with MSCs isolated from rabbit adipose, using collagen I hydrogel to encapsulate the ²-TCP scaffolds designed to enlarge the cells adhesion. The results demonstrated that the rabbit critical-sized bone defect could be completely repaired by the novel construct.

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