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- Circulating RNA may provide prognostic tool for multiple myeloma
- Rescuing the golgi puts brakes on Alzheimer’s progress
- An unholy alliance: Colon cancer cells in situ co-opt fibroblasts in surrounding tissue to break out
| Circulating RNA may provide prognostic tool for multiple myeloma Posted: 07 Dec 2014 06:16 AM PST The 'molecular mail' sent by multiple myeloma cells provides clues to how well patients with the disease are likely to respond to treatment, according to a new study.  |
| Rescuing the golgi puts brakes on Alzheimer’s progress Posted: 05 Dec 2014 08:35 AM PST Alzheimer's disease (AD) progresses inside the brain in a rising storm of cellular chaos as deposits of the toxic protein, amyloid-beta (Aβ), overwhelm neurons. An apparent side effect of accumulating Aβ in neurons is the fragmentation of the Golgi apparatus, the part of the cell involved in packaging and sorting protein cargo including the precursor of Aβ. But is the destruction the Golgi a kind of collateral damage from the Aβ storm or is the loss of Golgi function itself part of the driving force behind Alzheimer's?  |
| An unholy alliance: Colon cancer cells in situ co-opt fibroblasts in surrounding tissue to break out Posted: 05 Dec 2014 08:35 AM PST Researchers report that they have evidence of a coordinated attack on the basement membrane of human colon cells by cancer cells in situ and CAF cells in the extracellular matrix that begins long before the actual translocation of cancer cells.  |
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