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Mutations linked to genetic disorders shed light on a crucial DNA repair pathway Posted: 07 Aug 2015 07:07 PM PDT Researchers have identified two new genes in which mutations can interfere with a cell's ability to remove misplaced links between DNA strands, and, as a result, cause a rare genetic disorder known as Fanconi anemia. These discoveries offer new insight on a repair process critical to maintaining certain tissues and preventing cancer.

Pediatric brain tumors can be classified noninvasively at diagnosis Posted: 07 Aug 2015 11:43 AM PDT Medulloblastoma, the most commonly occurring malignant brain tumor in children, can be classified into four subgroups -- each with a different risk profile requiring subgroup-specific therapy. Investigators have now discovered that these subgroups can be determined non-invasively, using magnetic resonance spectroscopy.

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