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- New breast cancer drug may be effective against other types of cancer
- Body tightly controls inflammatory response to pathogens
- Psychotherapies have long-term benefit for those suffering from irritable bowel syndrome
- Scientists prevent, reverse diabetes-related kidney destruction in animal model
- Second contagious form of cancer found in Tasmanian devils
- Activity of Brain Proteins Associated with Memory Impairment in Alzheimer’s Identified
- Seaweed capsules may lead to an injection-free life for diabetic patients
- Choreographing the dance of electrons
- Scientists discover a new role for RNA in safeguarding human chromosome number
- 'Self-sabotage' prevents immune protection against malaria
- New antibodies with an extra fragment overcome malaria parasite diversity
- Genome misfolding unearthed as new path to cancer
- Positive results for new oral drug for pulmonary hypertension
- Mapping cancer's 'social networks' opens new approaches to treatment
- Targeting fat-tissue hormone may lead to type 2 diabetes treatment
New breast cancer drug may be effective against other types of cancer Posted: 29 Dec 2015 05:42 PM PST Palbociclib, a new oral drug whose efficacy in combating breast cancer has been demonstrated alone and in combination with endocrine therapy, also has potential to combat other types of cancer, according to a literature review and additional original research. |
Body tightly controls inflammatory response to pathogens Posted: 28 Dec 2015 01:13 PM PST The body can control inflammatory response triggered by invasions of microbial pathogens, such as bacteria and viruses, a discovery that could lead to the development of new therapeutic agents for uncontrolled inflammation, according to researchers. |
Psychotherapies have long-term benefit for those suffering from irritable bowel syndrome Posted: 28 Dec 2015 01:13 PM PST The beneficial effects of using psychological therapy to treat the symptoms of irritable bowel syndrome are not only short term but are also long lasting, a new meta-analysis has found. |
Scientists prevent, reverse diabetes-related kidney destruction in animal model Posted: 28 Dec 2015 01:12 PM PST Diabetes is the leading cause of kidney failure, and scientists have found that infusing just a small dose of a cytokine, thought to help cause that failure, can instead prevent or reverse it. |
Second contagious form of cancer found in Tasmanian devils Posted: 28 Dec 2015 01:12 PM PST Transmissible cancers are believed to arise extremely rarely in nature. One of the few known transmissible cancers causes facial tumors in Tasmanian devils, and is threatening this species with extinction. Today, scientists report the discovery of a second transmissible cancer in Tasmanian devils. The discovery calls into question our current understanding of the processes that drive cancers to become transmissible. |
Activity of Brain Proteins Associated with Memory Impairment in Alzheimer’s Identified Posted: 25 Dec 2015 11:18 AM PST Researchers at a laboratory for research of molecular and cellular mechanisms underlying learning and memory found that "repairing" the activity led to an improvement in memory. A start-up they established on the basis of the findings will attempt to develop drugs delaying the onset of cognitive symptoms. |
Seaweed capsules may lead to an injection-free life for diabetic patients Posted: 25 Dec 2015 11:18 AM PST A microencapsulation method can help to overcome major challenges in pancreatic islet transplantation, say researchers. The microencapsulation method can help to overcome some major challenges in pancreatic islet transplantation, including the scarcity of available islets and the lack of simple and reliable control methods, especially for individual islet assessment. It offers hope to patients suffering from type 1 diabetes to return to a "normal" life, free of insulin injections. |
Choreographing the dance of electrons Posted: 25 Dec 2015 11:15 AM PST Scientists have demonstrated a new way of controlling electrons by confining them in a device made out of atomically thin materials, and applying external electric and magnetic fields. |
Scientists discover a new role for RNA in safeguarding human chromosome number Posted: 25 Dec 2015 11:15 AM PST Molecular biologists have identified a gene called NORAD that helps maintain the proper number of chromosomes in cells, and that when inactivated, causes the number of chromosomes in a cell to become unstable, a key feature of cancer cells. |
'Self-sabotage' prevents immune protection against malaria Posted: 25 Dec 2015 11:15 AM PST Scientists have for the first time revealed how malaria parasites cause an inflammatory reaction that sabotages our body's ability to protect itself against the disease.The discovery opens up the possibility of improving new or existing malaria vaccines by boosting key immune cells needed for long-lasting immunity. This could even include vaccines that have previously been ineffective in clinical trials. |
New antibodies with an extra fragment overcome malaria parasite diversity Posted: 23 Dec 2015 07:17 PM PST A new groundbreaking mechanism that generates super-antibodies that can broadly target malaria parasites has been described in a new article. The antibodies described in this study were not only special for their broad reactivity, but also for their novel and surprising structure characterized by the presence of a large extra fragment, say the researchers. |
Genome misfolding unearthed as new path to cancer Posted: 23 Dec 2015 07:15 PM PST Researchers reveal a completely new biological mechanism that underlies cancer. By studying brain tumors that carry mutations in the isocitrate dehydrogenase genes, the team uncovered some unusual changes in the instructions for how the genome folds up on itself. |
Positive results for new oral drug for pulmonary hypertension Posted: 23 Dec 2015 07:15 PM PST Largest study ever of pulmonary hypertension shows effective treatment may get easier for the mostly young women patients who have the rare heart disease. The oral drug Selexipag reduced hospitalizations and worsening symptoms. |
Mapping cancer's 'social networks' opens new approaches to treatment Posted: 23 Dec 2015 07:15 PM PST A computer model has been designed that applies techniques used to analyze social networks to identify new ways of treating cancer, according to a new article. |
Targeting fat-tissue hormone may lead to type 2 diabetes treatment Posted: 23 Dec 2015 07:13 PM PST The preclinical development of a therapeutic that could potentially be used to treat type 2 diabetes, fatty liver disease, and other metabolic diseases has been outlined in a new report. The researchers developed an antibody that improves glucose regulation and reduces fatty liver in obese mice by targeting a hormone in adipose (fat) tissue called aP2 (also known as FABP4). |
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