ScienceDaily: Health & Medicine News

---

• Does daylight saving time increase risk of stroke?
• Less than half of pediatricians inquire about maternal mental health
• Study points to cannabis' effect on emotion processing
• Female fertility is dependent on functional expression of the E3 ubiquitin ligase Itch
• Diabetic management: Subcutaneous insulin therapy fails to protect against oxidative stress and inflammation
• A human liver microphysiology platform for studying physiology, drug safety, and disease
• A new way to discover DNA modifications
• Cancer patients with limited finances are more likely to have increased symptoms and poorer quality of life
• Two-way clustering method for QSAR modeling of diverse set of chemicals
• 'Informed consent' states often give women considering abortions inaccurate information
• Scientists find way to predict activity of stem cells
• Study finds 5x increase in hand sanitizer use when located in hospital
• New method may find elusive flaws in medical implants and spacecraft
• Metabolic phenotyping of blood plasma allows for the detection of lung cancer
• Childhood poverty, parental abuse cost adults their health for years to come
• Mutated gene associated with colon cancer discovered in 18th-century Hungarian mummy
• Is anti-TNF therapy safe for inflammatory bowel disease patients with prior cancer?
• Activity monitoring devices provide reliable records of activity
• Chronic conditions rise in older people
• Air data can be used to reconstruct radiological releases
• Blood vessels sprout under pressure
• Breast cancer genetic variants found to alter how cells respond to estrogen
• Are parents of 'difficult' children more likely to use iPads to calm kids down?
• Immune therapy breaks down wall around pancreatic tumors for chemo to attack
• I'll cry if i want to: Emotional exhaustion harms society's outcasts
• Nanotechnology delivery system offers new approach to skin disease therapies
• Genetic switch regulating satiety and body weight identified
• Ballooning 10 billion world population drives moderate-to-high worries, study finds
• Snoring in children can affect their health
• Two-pronged attack increases potency of new anti-cancer drugs
• Osteopathic manipulative treatment improves low back pain, avoid surgery, studies find
• Glucose-guzzling immune cells may drive coronary artery disease, study finds
• Understanding ageism prolongs your life
• New insight into the possible risk factors associated with food allergies
• New target for reducing nerve pain identified
• Making better enzymes and protein drugs
• 'Neoehrlichiosis' internationally diagnosed, successfully treated in patients without immunodeficiency for the first time
• Mammalian fertilization, caught on tape
• Cells in stiffer tissues are squeezed into mutating more often
• Tarantula toxins converted to painkillers
• Quick thinking and feeling healthy predict longer life
• Extracting value from chaos: The promise of health information technology
• Study finds consistent link between violent crime and concealed-carry gun permits
• Normal stem cells linked to aggressive prostate cancer
• Training needed to increase physician comfort level with transgender patients
• Predictive proteins: Elevated levels trigger metastatic progression of cancer cells
• Eylea outperforms Avastin for diabetic macular edema with moderate or worse vision loss
• Potential association between pre-labor Cesarean delivery and childhood leukemia IDed

Does daylight saving time increase risk of stroke? Posted: 29 Feb 2016 07:06 PM PST Turning the clock ahead or back one hour during daylight saving time transitions may be tied to an increased risk of ischemic stroke, but only temporarily, according to a preliminary study.

Less than half of pediatricians inquire about maternal mental health Posted: 29 Feb 2016 07:06 PM PST Although asking about maternal depression increased among pediatricians by about 30 percent between 2004 and 2013, less than half of pediatricians usually screen for the condition.

Study points to cannabis' effect on emotion processing Posted: 29 Feb 2016 03:27 PM PST According to researchers, cannabis significantly affects users' ability to recognize, process and empathize with human emotions like happiness, sadness and anger.

Female fertility is dependent on functional expression of the E3 ubiquitin ligase Itch Posted: 29 Feb 2016 03:26 PM PST Protein ubiquitination is known to result in its proteasomal degradation or to serve as a signal for tissue-specific cellular functions. Here it is reported that mice with a mutant form of the E3 ubiquitin ligase ITCH display reduced litter sizes due to a maternal effect. Mutant females had decreased numbers of implantations, corpa lutea, and extended estrous cycles. The results indicate for the first time that loss of functional ITCH disrupts female reproduction.

Diabetic management: Subcutaneous insulin therapy fails to protect against oxidative stress and inflammation Posted: 29 Feb 2016 03:25 PM PST Today, the gold standard for insulin therapy is the subcutaneous injection of insulin (CSII), despite a non-physiological route of administration with suboptimal glycemic control showed in some patients. Inability of CSII therapy to prevent inflammation and oxidative stress was firstly demonstrated in vivo on treated-diabetic rats, presenting a high variability of glycogen storage associated with glycemic fluctuations. This study suggests that targeting oxidative stress and/or inflammation could help the therapeutic management of diabetic patients.

A human liver microphysiology platform for studying physiology, drug safety, and disease Posted: 29 Feb 2016 03:25 PM PST Currently available animal and human liver models provide limited predictions of human drug efficacy and toxicity, primarily due to metabolic differences and the limited ability of simple 2-D models to recapitulate the complex cellular interactions that lead to toxicity. To fill this gap we have developed a novel 4 cell type, 3-D, microfluidic, human liver model with the ability to monitor multiple cellular toxicity and human disease related functions over at least 28 days.

A new way to discover DNA modifications Posted: 29 Feb 2016 03:25 PM PST DNA is made from four nucleosides, each known by its own letter -- A, G, C, and T. However, since the structure of DNA was deciphered in 1953, scientists have discovered several other variants that are often added to the DNA sequences to replace one of the usual four letters.

Cancer patients with limited finances are more likely to have increased symptoms and poorer quality of life Posted: 29 Feb 2016 03:25 PM PST If you're a lung or colorectal cancer patient, what's in your wallet could determine your level of suffering and quality of life during treatment, according to a new study.

Two-way clustering method for QSAR modeling of diverse set of chemicals Posted: 29 Feb 2016 12:32 PM PST New articles developed in silico models for the estimation of potential mutagenicity of chemicals from their structure without the input of any other experimental data.

'Informed consent' states often give women considering abortions inaccurate information Posted: 29 Feb 2016 12:31 PM PST Women considering abortions are getting medically inaccurate information nearly a third of the time in states that require doctors to provide informed consent materials to their patients, according to a new study.

Scientists find way to predict activity of stem cells Posted: 29 Feb 2016 11:01 AM PST Scientists have for the first time developed a way to predict how a specific type of stem cell will act against different diseases.

Study finds 5x increase in hand sanitizer use when located in hospital Posted: 29 Feb 2016 11:01 AM PST Placing alcohol-based hand sanitizers (AHS) in the middle of a hospital lobby floor in front of the visitor entrance increased visitor usage by 528 percent, according to a new study.

New method may find elusive flaws in medical implants and spacecraft Posted: 29 Feb 2016 11:01 AM PST Medical implants and spacecraft can suddenly go dead, often for the same reason: cracks in ceramic capacitors, devices that store electric charge in electronic circuits. These cracks, at first harmless and often hidden, can start conducting electricity, depleting batteries or shorting out the electronics. Now, researchers have demonstrated a nondestructive approach for detecting cracks in ceramic capacitors before they go bad.

Metabolic phenotyping of blood plasma allows for the detection of lung cancer Posted: 29 Feb 2016 11:01 AM PST Metabolic phenotyping of blood plasma by proton nuclear magnetic resonance identified unique metabolic biomarkers specific to lung cancer patients and allowed for the accurate identification of a cohort of patients with early and late-stage lung cancer.

Childhood poverty, parental abuse cost adults their health for years to come Posted: 29 Feb 2016 11:01 AM PST Growing up in poverty or being abused by parents can lead to accumulated health problems later in life, according to new research.

Mutated gene associated with colon cancer discovered in 18th-century Hungarian mummy Posted: 29 Feb 2016 11:01 AM PST A new discovery suggests that a genetic predisposition to cancer preceded the advent of modernization -- and, in a bizarre twist, they discovered this evidence in an 18th-century Hungarian mummy.

Is anti-TNF therapy safe for inflammatory bowel disease patients with prior cancer? Posted: 29 Feb 2016 10:59 AM PST A previous history of cancer doesn't necessarily preclude treatment with antibodies against tumor necrosis factor (anti-TNF) for patients with inflammatory bowel diseases, suggests a new study.

Activity monitoring devices provide reliable records of activity Posted: 29 Feb 2016 10:59 AM PST Fitbit, the popular physical activity monitoring device, is a valid and reliable way of monitoring physical activity, finds a new study.

Chronic conditions rise in older people Posted: 29 Feb 2016 10:53 AM PST The number of older people in England living with more than one chronic condition could have risen by 10 percent in the last decade putting increasing pressure on the NHS, new research has suggested.

Air data can be used to reconstruct radiological releases Posted: 29 Feb 2016 10:53 AM PST New research demonstrates that experts can use data from air sampling technology to not only detect radiological releases, but to accurately quantify the magnitude and source of the release. This has applications for nuclear plant safety, as well as national security and nuclear nonproliferation monitoring.

Blood vessels sprout under pressure Posted: 29 Feb 2016 10:53 AM PST It is blood pressure that drives the opening of small capillaries during angiogenesis. A team of researchers has observed the process for the first time.

Breast cancer genetic variants found to alter how cells respond to estrogen Posted: 29 Feb 2016 10:51 AM PST An international study of almost 120,000 women has newly identified five genetic variants affecting risk of breast cancer, all of which are believed to influence how breast cells respond to the female sex hormone estrogen.

Are parents of 'difficult' children more likely to use iPads to calm kids down? Posted: 29 Feb 2016 10:51 AM PST It may be tempting to hand an iPad or Smartphone to a tantrum-throwing child -- and maybe more so for some parents. A study shows that devices were more likely to be used as a coping strategy to pacify children with difficult behavior. However, there were no differences between children with social-emotional difficulties and other children when it came to mobile technology use during other scenarios, such as eating, being in public, doing chores or at bedtime.

Immune therapy breaks down wall around pancreatic tumors for chemo to attack Posted: 29 Feb 2016 08:20 AM PST In a new preclinical study, researchers have uncovered the poorly understood mechanics of how macrophages can be "re-educated" by an experimental immune therapy to help tear down the scaffolding that surrounds and protects pancreas cancer from chemotherapy.

I'll cry if i want to: Emotional exhaustion harms society's outcasts Posted: 29 Feb 2016 08:20 AM PST Most theories suggest some people are willing to view stigmatized individuals, such as drug addicts, as less than human because believing people in these situations don't have the capacity to think and feel like others makes it easier to marginalize them. Research has now found another reason why people may dehumanize society's outcasts: emotional exhaustion.

Nanotechnology delivery system offers new approach to skin disease therapies Posted: 29 Feb 2016 08:18 AM PST Researchers have developed a nanotechnology-based delivery system containing a protective cellular pathway inducer that activates the body's natural defense against free radicals efficiently, a development that could control a variety of skin pathologies and disorders.

Genetic switch regulating satiety and body weight identified Posted: 29 Feb 2016 08:12 AM PST A team of researchers has identified a new mechanism that regulates the effect of the satiety hormone leptin. The study identified the enzyme HDAC5 as key factor in our control of body weight and food intake and potential target against the Yoyo dieting effect.

Ballooning 10 billion world population drives moderate-to-high worries, study finds Posted: 29 Feb 2016 06:59 AM PST Risk analysts have gathered new evidence that the public sees a medium-to-high risk that worldwide population growth could lead to food and water shortages, species extinctions, and other disasters, pointing to the likelihood that concerned individuals might support policies to slow the growth.

Snoring in children can affect their health Posted: 29 Feb 2016 06:56 AM PST Children commonly snore from time to time and that is often harmless. But children with frequent snoring and breathing problems during sleep have an increased risk of having trouble concentrating and learning difficulties. A newly published study shows that many parents of children that snore are not aware of the possible risks associated with frequent snoring in children.

Two-pronged attack increases potency of new anti-cancer drugs Posted: 29 Feb 2016 06:54 AM PST Researchers have discovered that the treatment of the most deadly form of blood cancer may be improved by combining two recently developed drugs.

Osteopathic manipulative treatment improves low back pain, avoid surgery, studies find Posted: 29 Feb 2016 06:54 AM PST Osteopathic manipulative treatment reduced pain and improved function in patients suffering from chronic, nonspecific low back pain, research shows. Further, patients reporting the worst pain and higher degrees of disability received the most substantial benefit from the treatments.

Glucose-guzzling immune cells may drive coronary artery disease, study finds Posted: 29 Feb 2016 06:54 AM PST Hyper-aggressive immune cells parked in arterial plaque and feeding on glucose appear to be major drivers of coronary artery disease, investigators have found.

Understanding ageism prolongs your life Posted: 29 Feb 2016 05:22 AM PST Perceptions about ageism makes people think of older people and is a form of discrimination. This according to a researcher who believes that the concept needs to be redefined to mirror all people's practical experiences of aging.

New insight into the possible risk factors associated with food allergies Posted: 29 Feb 2016 05:22 AM PST Food hypersensitivity is the umbrella term used to describe any condition where there is a reaction to a food. People are tested by measuring levels of a protein in the blood - immunoglobulin E (IgE) - which is linked to allergic reactions. A new study is the first to assess the prevalence of two different types of food hypersensitivity and the risk factors associated with them.

New target for reducing nerve pain identified Posted: 29 Feb 2016 05:21 AM PST A specific molecule involved in maintaining pain after a nerve injury has been identified and blocked in mice by researchers. These results reveal a promising therapeutic strategy for treating neuropathic pain.

Making better enzymes and protein drugs Posted: 29 Feb 2016 05:21 AM PST Natural selection results in protein sequences that are only soluble to the level that is required to carry out its physiological function. However, in biotechnological applications, we need these proteins to survive concentrations that are up to 1000-fold higher that what naturally occurs, e.g. an antibody drug in the syringe prior to injection. Because of this, biotechnological and therapeutic applications of protein are often hampered or rendered impossible by the mismatch between the natural solubility of a protein and the requirements of the application. This raises the question whether the solubility of natural protein sequences could be improved without affecting their intended function.

'Neoehrlichiosis' internationally diagnosed, successfully treated in patients without immunodeficiency for the first time Posted: 29 Feb 2016 05:21 AM PST The intercellular bacteria "Candidatus Neoehrlichia", as e.g. Borrelia, can be transferred by ticks. Approx. 4.2 % of indigenous ticks are infected with this rarely explored bacterium which, until today, has been exclusively identified as pathogenic bacterium in patients with an impairment of the immune system, such as in case of leukemia, rheumatism or after organ transplantation. Now, an interdisciplinary team of researchers has succeeded in diagnosing the bacterium in an otherwise healthy female patient with fever of an unknown origin - and treating it successfully.

Mammalian fertilization, caught on tape Posted: 29 Feb 2016 05:20 AM PST The development of every animal in the history of the world began with a simple step: the fusion of a spermatozoon with an oocyte. Despite the ubiquity of this process, the actual mechanisms through which fertilization occurs remain poorly understood. A new tool developed by a team of biophysicists may soon shed light on this still-mysterious process, and has already captured highly detailed images of what happens when sperm and egg first touch.

Cells in stiffer tissues are squeezed into mutating more often Posted: 29 Feb 2016 05:20 AM PST When it comes to cancerous mutations, cells in soft tissues like bone marrow and the brain tend to exhibit fewer irregularities than their stiffer somatic brethren in the lungs or bone. According to researchers, this isn't only due to differences between the cells' type and function, but also to the rigid forces of resistance that act on them when they move and divide.

Tarantula toxins converted to painkillers Posted: 29 Feb 2016 05:20 AM PST When venom from animals such as spiders, snakes or cone snails is injected via a bite or harpoon, the cocktail of toxins delivered to its victim tends to cause serious reactions that, if untreated, can be lethal. But even venom has a therapeutic upside: Individual peptide toxins are being tapped to target receptors in the brain to potentially serve as painkillers.

Quick thinking and feeling healthy predict longer life Posted: 29 Feb 2016 05:19 AM PST Suffering from chronic medical conditions and engaging in unhealthy behaviors are known risk factors for early death, but findings from a longitudinal study of over 6,000 adults suggests that certain psychological factors may be even stronger predictors of how long we'll live.

Extracting value from chaos: The promise of health information technology Posted: 29 Feb 2016 05:19 AM PST A new article takes a sweeping look at a variety of categories of health IT including electronic medical records; health information exchange; telemedicine; patient portals and personal health records; mobile devices, wearable sensors and monitors; and social media. The authors evaluate current use of these technologies, detail their potential and discuss barriers that must be overcome to fulfill their promise of improving health.

Study finds consistent link between violent crime and concealed-carry gun permits Posted: 29 Feb 2016 05:19 AM PST A new study finds a significant relationship between firearm crime and subsequent applications for, and issuance of, concealed-carry gun permits.

Normal stem cells linked to aggressive prostate cancer Posted: 29 Feb 2016 05:18 AM PST A study that revealed new findings about prostate cells may point to future strategies for treating aggressive and therapy-resistant forms of prostate cancer, report scientists.

Training needed to increase physician comfort level with transgender patients Posted: 29 Feb 2016 05:18 AM PST A first-of-its-kind survey assessing the attitudes and practice patterns of transgender care by endocrinologists, who often treat transgender patients with hormone therapy, has been released by researchers.

Predictive proteins: Elevated levels trigger metastatic progression of cancer cells Posted: 28 Feb 2016 05:19 AM PST Researchers have unraveled how elevated levels of particular proteins in cancer cells trigger hyperactivity in other proteins, fueling the growth and spread of a variety of cancers.

Eylea outperforms Avastin for diabetic macular edema with moderate or worse vision loss Posted: 27 Feb 2016 08:07 AM PST A two-year clinical trial that compared three drugs for diabetic macular edema (DME) found that gains in vision were greater for participants receiving the drug Eylea (aflibercept) than for those receiving Avastin (bevacizumab), but only among participants starting treatment with 20/50 or worse vision. Gains after two years were about the same for Eylea and Lucentis (ranibizumab), contrary to year-one results from the study, which showed Eylea with a clear advantage. The three drugs yielded similar gains in vision for patients with 20/32 or 20/40 vision at the start of treatment.

Potential association between pre-labor Cesarean delivery and childhood leukemia IDed Posted: 27 Feb 2016 08:07 AM PST A potential correlation between pre-labor Cesarean delivery (PLCD) and acute lymphoblastic leukemia (ALL) could offer new targets for cancer prevention research, according to new research.

You are subscribed to email updates from Health & Medicine News -- ScienceDaily. To stop receiving these emails, you may unsubscribe now.	Email delivery powered by Google
Google Inc., 1600 Amphitheatre Parkway, Mountain View, CA 94043, United States