ScienceDaily: Health & Medicine News

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• Global study shows diabetes and heart disease can be a deadly combination
• Older Americans with diabetes living longer without disability, US study shows
• Eye study underscores the long-lasting benefits of controlling diabetes
• Weight and diet may help predict sleep quality
• Implantable device cuts obstructive sleep apnea symptoms
• Amino acid identified associated with poor performance under sleep restriction
• Alzheimer's researchers find clues to toxic forms of amyloid beta
• Female sex hormone clue to fighting serious immune disease
• Genetic clue to development of mouth ulcers in lupus
• Prolonged repetitive physical workload increases risk of developing rheumatoid arthritis
• Scoliosis linked to disruptions in spinal fluid flow
• Damage to tiny liver protein function leads to heart disease, fatty liver
• Many with migraines have vitamin deficiencies, says study
• New tool brings personalized medicine closer
• Discovery of molecular protection linked to a degenerative neuromuscular disease
• Peanut allergy prevention strategy is nutritionally safe, study suggests
• The Hawthorne Effect hinders accurate hand hygiene observation, study says
• Environmental, health impacts of US health-care system
• Researchers track HIV in real time as it infects, spreads in living tissue
• Rapid retrieval of live, infectious pathogens from clinical samples
• Body's own gene editing system generates leukemia stem cells
• Researchers discover a mechanism that reverses resistance to antiangiogenic drugs
• New molecules identified that could help in the fight to prevent cystic fibrosis
• Cellular 'racetrack' accurately clocks brain cancer cell movement
• Enzyme keeps antibodies from targeting DNA, driving inflammation in lupus
• New biomarker for nerve cell damage
• Study sets standards for evaluating pluripotent stem cell quality

Global study shows diabetes and heart disease can be a deadly combination Posted: 11 Jun 2016 01:56 PM PDT New research has found that patients with type 2 diabetes admitted into the hospital for congestive heart failure face a one in four chance of dying within 18 months. Patients with type 2 diabetes have two to three times the heart disease risk of the general population, but the findings paint a grimmer picture of the outcome for diabetes patients with severe heart disease than was known.

Older Americans with diabetes living longer without disability, US study shows Posted: 11 Jun 2016 09:53 AM PDT Older Americans with diabetes born in the 1940s are living longer and with less disability performing day to day tasks than those born 10 years earlier, according to new research.

Eye study underscores the long-lasting benefits of controlling diabetes Posted: 11 Jun 2016 09:53 AM PDT People with type 2 diabetes who intensively controlled their blood sugar level during the landmark ACCORD Trial Eye Study were found to have cut their risk of diabetic retinopathy in half in a follow-up analysis conducted four years after stopping intensive therapy.

Weight and diet may help predict sleep quality Posted: 10 Jun 2016 02:36 PM PDT The old adage 'you are what you eat,' may be better phrased as 'your sleep relates to what you eat.' An individual's body composition and caloric intake can influence time spent in specific sleep stages, according to results of a new study.

Implantable device cuts obstructive sleep apnea symptoms Posted: 10 Jun 2016 02:36 PM PDT Since the 1980s, continuous positive airway pressure (CPAP) -- in which positive pressure is pushed through the nasal airways to help users breathe while sleeping - has been by far the most widely used treatment for obstructive sleep apnea (OSA). With more than 18 million people experiencing OSA, a number expected to rise, new results from a case study of a new device implanted in the chest called hypoglossal nerve stimulation (HGNS) offers promise for patients with moderate to severe OSA who cannot tolerate CPAP.

Amino acid identified associated with poor performance under sleep restriction Posted: 10 Jun 2016 02:36 PM PDT The amino acid acetylcarnitine may help predict an individual's neurobehavioral performance during chronic sleep restriction, according to new results.

Alzheimer's researchers find clues to toxic forms of amyloid beta Posted: 10 Jun 2016 02:36 PM PDT Much of the research on Alzheimer's disease has focused on the amyloid beta protein, which clumps together into sticky fibrils that form deposits in the brains of people with the disease. In recent years, attention has turned away from the fibrils themselves to an intermediate stage in the aggregation of amyloid beta. A new study helps lift the veil on the structure and behavior of these neurotoxic 'oligomers.'

Female sex hormone clue to fighting serious immune disease Posted: 10 Jun 2016 02:36 PM PDT The results of a study showed for the first time a beneficial effect of estrogens in experimental models of skin fibrosis that are representative of the disease process in systemic sclerosis (SSc). These findings may explain the increased incidence of SSc in women after the menopause, the greater severity of SSc in men, and importantly open up the possibility of developing potential hormone therapies for this difficult-to-treat condition.

Genetic clue to development of mouth ulcers in lupus Posted: 10 Jun 2016 02:35 PM PDT The results of a new study showed for the first time an association between a specific genetic pathway and the development of mouth ulcers in patients with Systemic Lupus Erythematosus (SLE). Linking the vascular endothelial growth factor (VEGF) genetic pathway with a specific disease characteristic among SLE patients represents an important step towards unravelling the genetic basis of different SLE clinical presentations.

Prolonged repetitive physical workload increases risk of developing rheumatoid arthritis Posted: 10 Jun 2016 02:35 PM PDT The results of a new study showed that prolonged repetitive physical workload increases the risk of developing rheumatoid arthritis (RA). Although work-related physical activity over many years is known to cause many cases of osteoarthritis (OA) in selected joints, this is the first study to show a link between physical workload and RA.

Scoliosis linked to disruptions in spinal fluid flow Posted: 10 Jun 2016 11:08 AM PDT Irregular fluid flow through the spinal column brought on by gene mutations is linked to a type of scoliosis that can affect humans during adolescence, a new study in zebrafish suggests. Also found in people, these genes damage the hair-like projections called motile cilia that move fluid through the spinal canal and lead to a curvature of the spine.

Damage to tiny liver protein function leads to heart disease, fatty liver Posted: 10 Jun 2016 11:07 AM PDT For the first time, it has been discovered that a tiny liver protein that when disrupted can lead to the nation's top killer -- cardiovascular disease -- as well as fatty liver disease, a precursor to cancer.

Many with migraines have vitamin deficiencies, says study Posted: 10 Jun 2016 11:06 AM PDT A high percentage of children, teens and young adults with migraines appear to have mild deficiencies in vitamin D, riboflavin and coenzyme Q10 -- a vitamin-like substance found in every cell of the body that is used to produce energy for cell growth and maintenance.

New tool brings personalized medicine closer Posted: 10 Jun 2016 09:18 AM PDT A powerful tool for exploring and determining the inherent biological differences between individuals, has now been developed, which overcomes a major hurdle for personalized medicine.

Discovery of molecular protection linked to a degenerative neuromuscular disease Posted: 10 Jun 2016 08:27 AM PDT Kennedy's disease leads to progressive muscle wastage. It is a condition that affects only men and it appears between 40 and 50 years of age. There is no specific treatment available. In individuals with this disease, muscle cells and motor neurons die over the years because they accumulate a protein that is mutated. Researchers discover that this protein has a self-protective mechanism through which the deleterious effects of the mutation are delayed.

Peanut allergy prevention strategy is nutritionally safe, study suggests Posted: 10 Jun 2016 06:47 AM PDT Introducing peanut-containing foods during infancy as a peanut allergy prevention strategy does not compromise the duration of breastfeeding or affect children's growth and nutritional intakes, new findings show.

The Hawthorne Effect hinders accurate hand hygiene observation, study says Posted: 10 Jun 2016 06:44 AM PDT When healthcare providers know they are being watched, they are twice as likely to comply with hand hygiene guidelines. This is in comparison to when healthcare providers do not know someone is watching, according to a new study. This phenomenon -- called The Hawthorne Effect -- impacts the ability to capture accurate human behavior because individuals modify their actions when they know they are being observed.

Environmental, health impacts of US health-care system Posted: 09 Jun 2016 12:12 PM PDT If the US health-care system were a country, it would rank 13th in the world for greenhouse gas emissions, according to new research. The study quantified previously unreported environmental and public health impacts of the nation's healthcare sector.

Researchers track HIV in real time as it infects, spreads in living tissue Posted: 09 Jun 2016 10:45 AM PDT By watching brightly glowing HIV-infected immune cells move within mice, researchers have shown how infected immune cells latch onto an uninfected sister cell to directly transmit newly minted viral particles. The research challenges the long-held perception that the primary route of HIV infection of immune cells is from free-floating viral particles that move within tissue and blood fluids.

Rapid retrieval of live, infectious pathogens from clinical samples Posted: 09 Jun 2016 10:45 AM PDT Scientists now reports a method which enables the rapid isolation and concentration of infectious bacteria from complex clinical samples to help speed up bacterial identification, and it should be able to accelerate the determination of antibiotic susceptibilities as well.

Body's own gene editing system generates leukemia stem cells Posted: 09 Jun 2016 10:44 AM PDT Cancer stem cells are like zombies -- even after a tumor is destroyed, they can keep coming back. These cells have an unlimited capacity to regenerate themselves, making more cancer stem cells and more tumors. Researchers have now unraveled how pre-leukemic white blood cell precursors become leukemia stem cells.

Researchers discover a mechanism that reverses resistance to antiangiogenic drugs Posted: 09 Jun 2016 10:43 AM PDT Researchers have just published an important finding regarding antiangiogenic drugs. In the article they describe a resistance mechanism to these compounds and, more importantly, a way to reverse it. Working on mice with breast and lung cancer, they noted that when they added an antidiabetic agent to the antiangiogenic drug regimen, tumor growth was inhibited by 92 percent.

New molecules identified that could help in the fight to prevent cystic fibrosis Posted: 09 Jun 2016 10:43 AM PDT New research has identified new molecules that could help in the fight to prevent diseases caused by faulty ion channels, such as cystic fibrosis.

Cellular 'racetrack' accurately clocks brain cancer cell movement Posted: 09 Jun 2016 10:42 AM PDT Researchers have developed an experimental laboratory test that accurately clocks the 'speed' of human brain tumor cell movement along a small glass 'track.' The assay, so far tested on the cells of 14 glioblastoma patients, has the potential, they say, to predict how quickly and aggressively a given cancer might lethally spread.

Enzyme keeps antibodies from targeting DNA, driving inflammation in lupus Posted: 09 Jun 2016 10:42 AM PDT Failure of an enzyme to break down DNA spilling into the bloodstream as cells die may be a major driver of inflammation in lupus, report scientists.

New biomarker for nerve cell damage Posted: 09 Jun 2016 10:42 AM PDT Scientists have identified proteins in the blood and cerebrospinal fluid that reflect nerve cell damage. The results of the study suggest that the concentration of these 'neurofilament light chain proteins' could provide information about the progression of neurodegenerative diseases and the effects of treatment. Such a biomarker would be valuable for developing therapies.

Study sets standards for evaluating pluripotent stem cell quality Posted: 09 Jun 2016 10:42 AM PDT As the promise of using regenerative stem cell therapies draws closer, a consortium of biomedical scientists reports about 30 percent of induced pluripotent stem cells they analyzed from 10 research institutions were genetically unstable and not safe for clinical use. In a new study, the multi-institutional research team reports on the comprehensive characterization of a large set of induced pluripotent stem cells (iPSCs).

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