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- Scientists grow mini human brains
- Krüppel-like factor 12 promotes colorectal cancer via early growth response protein 1
- Lab method sheds light on how genetic mutations cause inherited Parkinson's disease
- Indian pedestrian, motorcycle deaths likely much higher than government data suggest
- Hybrid treatment hunts down and kills leukemia cells
- How can we reduce US firearm suicide rates?
- Study verifies human gene therapy in model of rare metabolic disorder
- Discoveries offer hope for managing ovarian cancer
- New genetic syndrome tied to defects in protein transport
- Novel drug therapy kills pancreatic cancer cells by reducing levels of antioxidants
- Scientists discover new therapeutic target for lung cancer driven by KRAS
Scientists grow mini human brains Posted: 30 Jul 2016 12:45 PM PDT Mini midbrains provide next generation platforms to investigate human brain biology, diseases and therapeutics, report scientists. |
Krüppel-like factor 12 promotes colorectal cancer via early growth response protein 1 Posted: 29 Jul 2016 10:29 AM PDT Investigators report preclinical research showing that Krüppel-like factor 12 promotes colorectal cancer cell growth by activating early growth response protein 1. Data also reveal that levels of KLF12 and EGR1 correlate synergistically with a poor CRC prognosis. Results indicate that KLF12 plays an important role in CRC progression and provides a potential novel prognostic marker and therapeutic target. |
Lab method sheds light on how genetic mutations cause inherited Parkinson's disease Posted: 29 Jul 2016 06:25 AM PDT Scientists have developed a new method of measuring the activity of disease-causing mutations in the LRRK2 gene, a major cause of inherited Parkinson's disease. |
Indian pedestrian, motorcycle deaths likely much higher than government data suggest Posted: 28 Jul 2016 04:55 PM PDT Official government statistics on traffic deaths in southwest India significantly misrepresented the number of pedestrian and motorcycle deaths in the region over a two-year period, casting doubt on the reliability of that country's government data on traffic fatalities, a study suggests. |
Hybrid treatment hunts down and kills leukemia cells Posted: 28 Jul 2016 12:56 PM PDT Researchers have developed a hybrid treatment that harnesses a monoclonal antibody to deliver antisense DNA to acute lymphoblastic leukemia (ALL) cells and that may lead to less toxic treatments for the disease. |
How can we reduce US firearm suicide rates? Posted: 28 Jul 2016 12:50 PM PDT Reducing firearm access, smart gun technology, and public education could reduce firearm suicides in the United States, finds a new report. |
Study verifies human gene therapy in model of rare metabolic disorder Posted: 28 Jul 2016 11:36 AM PDT Researchers are closer to finding a better way to treat children with a rare metabolic disorder called MPS I. |
Discoveries offer hope for managing ovarian cancer Posted: 28 Jul 2016 11:33 AM PDT A protein discovery offers a possible test for ovarian cancer, report scientists. The research team also identified an enzyme vital to ovarian cancer growth and spread, offering a target for new treatments. In ovarian cancer, early detection and treatment are vital; this research offers routes to both. |
New genetic syndrome tied to defects in protein transport Posted: 28 Jul 2016 11:33 AM PDT An international team of researchers has discovered the mutation responsible for a rare, newly identified genetic disorder that causes craniofacial abnormalities and developmental delays. The mutation disrupts normal protein transport within cells, shedding light on a fundamental process in cell biology and early human development. The syndrome represents a novel class of disorders. |
Novel drug therapy kills pancreatic cancer cells by reducing levels of antioxidants Posted: 28 Jul 2016 11:32 AM PDT While it's a matter of conventional wisdom in popular culture that raising antioxidant levels in the body tends to keep cancer at bay, a research team demonstrates that in pancreatic cells on the road to cancer or already malignant, the last thing one wants to do is to raise antioxidant levels. Lowering antioxidants in pancreatic cancer cells can help kill them, the study shows. |
Scientists discover new therapeutic target for lung cancer driven by KRAS Posted: 28 Jul 2016 09:57 AM PDT Researchers have identified a new way to target lung cancer through the KRAS gene, one of the most commonly mutated genes in human cancer and one researchers have so far had difficulty targeting successfully. |
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