ScienceDaily: Health & Medicine News

---

• Mechanism identified through which lead may harm neural cells, children's neurodevelopment
• Researchers find a new way to identify, target malignant aging in leukemia
• Sensor systems identify senior citizens at risk of falling within 3 weeks
• Mechanical force triggers gene expression by stretching chromatin
• Breast milk sugar may protect babies against deadly infection
• Egyptian women say doctors don't discourage female genital cutting, study finds
• Insecticide ryanodine: Building a chemical from the ground up
• Allergy research: Response to house dust mites is age-dependent
• Banning tobacco sales near schools could reduce socioeconomic disparities, new study shows
• Important advance made with new approach to 'control' cancer, not eliminate it
• Physicist's DNA chip offers big possibilities in cell, cancer studies
• Stiff arteries linked with memory problems, mouse study suggests
• Sights set on the next generation of shuttle peptides to target the brain
• Acute virus infection associated with sensory polyneuropathy, Zika experts say
• Researchers succeed in developing a genome editing technique that does not cleave DNA
• Scientists shed new light on the role of calcium in learning, memory
• Novel inhibitory brain receptor may be mechanism for remission of epilepsy in adolescence
• Discovery of a novel Wnt inhibitor with potential to eradicate colorectal cancer stem cells, report researchers
• Physician advice to patients on e-cigarettes varies, reveals knowledge gaps, study shows
• Experts say inexpensive drug could slow heart disease for type 1 diabetic patients
• Israeli lifestyle, environment may pose exceptional risks for Hodgkin's lymphoma
• US teens more likely to vape for flavorings than nicotine in e-cigarettes
• New test needed to assess the quality, safety of sunglasses
• Designing ultrasound tools with Lego-like proteins
• Neuroscientists stand up for basic cell biology research
• Symmetry crucial for building key biomaterial collagen in the lab
• In sub-Saharan Africa, cancer can be an infectious disease
• Fused genes found in esophageal cancer cells offer new clues on disease mechanisms
• Solving a 48 year old mystery: Scientists grow noroviruses in human intestinal cell cultures
• New diagnostic instrument sees deeper into the ear
• Researchers find roots of modern humane treatment
• Manufacturing pharmaceutical and other valuable chemicals: Better decisions
• New study finds low transfer rates of pediatric burn patients in the United States
• Finally, the brain sensor that turns down the heat
• Vouchers help get health goods to those most in need
• Factors that might attract children to marijuana edibles
• Fracking chemicals exposure may harm fertility in female mice
• Children with food allergies predisposed to asthma, rhinitis
• Researchers find new role for cannabinoids in vision
• Successful recycling: Protein quality control in the cell
• Risk of adolescents being overweight impacted by neighborhood education, income levels
• Hormone activation of genes takes teamwork
• New research reveals cancers need a 'perfect storm' of conditions to develop
• How PSD forms and why defects can cause autism
• Insights on lung micro-environment explain why cancer spreads to the lungs
• Men perceived as younger, more attractive after hair transplant for baldness
• Study examines financial conflict of interests among NCCN guideline authors
• Oxygen can impair cancer immunotherapy in mice
• Study shows protein complex essential to creating healthy blood cells
• Calorie-burning 'good' fat can be protected
• Scientists discover structural clues to calcium regulation in cells

Mechanism identified through which lead may harm neural cells, children's neurodevelopment Posted: 26 Aug 2016 12:15 PM PDT Researchers have identified a potential molecular mechanism through which lead, a pervasive environmental toxin, may harm neural stem cells and neurodevelopment in children.

Researchers find a new way to identify, target malignant aging in leukemia Posted: 26 Aug 2016 11:23 AM PDT Researchers have identified RNA-based biomarkers that distinguish between normal, aging hematopoietic stem cells and leukemia stem cells associated with secondary acute myeloid leukemia (sAML), a particularly problematic disease that typically afflicts older patients who have often already experienced a bout with cancer.

Sensor systems identify senior citizens at risk of falling within 3 weeks Posted: 26 Aug 2016 11:23 AM PDT Each year, millions of people -- especially those 65 and older -- fall. Such falls can be serious, leading to broken bones, head injuries, hospitalizations or even death. Now, researchers have found that sensors that measure in-home gait speed and stride length can predict likely falls. This technology can assist health providers to detect changes and intervene before a fall occurs.

Mechanical force triggers gene expression by stretching chromatin Posted: 26 Aug 2016 11:23 AM PDT How genes in our DNA are expressed into traits within a cell is a complicated mystery with many players, the main suspects being chemical. However, a new study has demonstrated that external mechanical force can directly regulate gene expression. The study also identified the pathway that conveys the force from the outside of the cell into the nucleus.

Breast milk sugar may protect babies against deadly infection Posted: 26 Aug 2016 07:48 AM PDT A type of sugar found naturally in some women's breast milk may protect newborn babies from infection with a potentially life threatening bacterium called Group B streptococcus, according to a new study. These bacteria are a common cause of meningitis in newborns and the leading cause of infection in the first three months of life globally.

Egyptian women say doctors don't discourage female genital cutting, study finds Posted: 26 Aug 2016 07:48 AM PDT More Egyptian women are seeking the opinions of physicians on whether their daughters should undergo female genital cutting, which is illegal in the country, but they say doctors don't advise against the procedure.

Insecticide ryanodine: Building a chemical from the ground up Posted: 26 Aug 2016 07:48 AM PDT Chemists have significantly improved upon the synthesis of a molecule related to muscle and neuronal function. A research team has been busy trying to crack the puzzle of the insecticide ryanodine, a complex molecule first isolated from a tropical plant in the 1940s. Ryanodine paralyzes insects by binding to a class of calcium-channel receptors called ryanodine receptors. In humans, these receptors play critical roles in muscle and neuronal function.

Allergy research: Response to house dust mites is age-dependent Posted: 26 Aug 2016 07:15 AM PDT In adults with a house dust mite allergy, a cascade of inflammatory signals on the surface of the airways leads to airway remodeling. This process cannot be influenced by standard cortisone therapy.

Banning tobacco sales near schools could reduce socioeconomic disparities, new study shows Posted: 26 Aug 2016 07:15 AM PDT Banning tobacco sales within 1,000 feet of schools could reduce socioeconomic and racial/ethnic disparities in tobacco density across neighborhoods, according to a study.

Important advance made with new approach to 'control' cancer, not eliminate it Posted: 26 Aug 2016 06:27 AM PDT Researchers have created a new drug delivery system that could improve the effectiveness of an emerging concept in cancer treatment -- to dramatically slow and control tumors on a long-term, sustained basis, not necessarily aiming for their complete elimination.

Physicist's DNA chip offers big possibilities in cell, cancer studies Posted: 26 Aug 2016 05:43 AM PDT A physicist has developed a novel technology that not only sheds light on basic cell biology, but also may aid in the development of more effective cancer treatments or early diagnosis of disease.

Stiff arteries linked with memory problems, mouse study suggests Posted: 26 Aug 2016 05:43 AM PDT Using a new mouse model, researchers have found that stiffer arteries can also negatively affect memory and other critical brain processes. The findings may eventually reveal how arterial stiffness leads to Alzheimer's and other diseases involving dementia.

Sights set on the next generation of shuttle peptides to target the brain Posted: 26 Aug 2016 05:40 AM PDT There is a new and emerging field of drug transporters that have the capacity to reach the brain more efficiently, say researchers, bringing together chemistry, pharmacy and biomedicine.

Acute virus infection associated with sensory polyneuropathy, Zika experts say Posted: 26 Aug 2016 05:39 AM PDT A group of researchers has described the first case of sensory polyneuropathy associated with acute Zika virus infection. A large percentage of people suffering from Zika virus infections are asymptomatic or show only mild symptoms. But potential neurological complications can be dramatic.

Researchers succeed in developing a genome editing technique that does not cleave DNA Posted: 26 Aug 2016 05:39 AM PDT A research team has succeeded in developing 'Target-AID', a genome editing technique that does not cleave the DNA. The technique offers, through high-level editing operation, a method to address the existing issues of genome editing. It is expected that the technique will be applied to gene therapy in the future in addition to providing a powerful tool for breeding useful organisms and conducting disease and drug-discovery research.

Scientists shed new light on the role of calcium in learning, memory Posted: 26 Aug 2016 05:39 AM PDT While calcium's importance for our bones and teeth is well known, its role in neurons—in particular, its effects on processes such as learning and memory—has been less well defined. A new study offers insights into how calcium in mitochondria -- the powerhouse of all cells -- can impact the development of the brain and adult cognition.

Novel inhibitory brain receptor may be mechanism for remission of epilepsy in adolescence Posted: 26 Aug 2016 05:38 AM PDT At the onset of puberty, the emergence of a novel inhibitory brain receptor reduces seizure-like activity in a mouse model of epilepsy.

Discovery of a novel Wnt inhibitor with potential to eradicate colorectal cancer stem cells, report researchers Posted: 26 Aug 2016 05:38 AM PDT A team of researchers has announced the development of a novel small-molecule Wnt inhibitor named NCB-0846. Wnt signaling is a key pathway of cancer stem cell development. The inhibitor may provide a new therapy option for patients with drug-refractory colorectal cancer.

Physician advice to patients on e-cigarettes varies, reveals knowledge gaps, study shows Posted: 26 Aug 2016 05:38 AM PDT Researchers analyzed an online medical forum to better understand what patients want to know about e-cigarettes and how doctors respond to those questions.

Experts say inexpensive drug could slow heart disease for type 1 diabetic patients Posted: 25 Aug 2016 06:43 PM PDT Scientists believe a drug commonly prescribed for type 2 diabetes could be routinely taken by type 1 diabetic patients to slow the development or delay heart disease.

Israeli lifestyle, environment may pose exceptional risks for Hodgkin's lymphoma Posted: 25 Aug 2016 06:43 PM PDT In Israel, the incidence of Hodgkin's lymphoma (HL) is among the highest in the world and has risen sharply over the past 45 years. Researchers found an association between being born in Israel and occurrence of HL, and an elevated risk of HL within one generation of moving to Israel. This could point to environmental causes such as exposures, diet, climate, social environment, and stress related to chronic regional conflict.

US teens more likely to vape for flavorings than nicotine in e-cigarettes Posted: 25 Aug 2016 06:43 PM PDT US teens are more likely to vape for the flavorings found in e-cigarettes rather than nicotine, suggests research. It is widely assumed that teen vapers are vaping nicotine, so in a bid to find out exactly what substances they are vaping, the researchers quizzed almost 15,000 students about their vaping experiences.

New test needed to assess the quality, safety of sunglasses Posted: 25 Aug 2016 06:43 PM PDT Exposure to the sun may deteriorate your sunglasses over time and the lenses may become lighter and so alter the category under which they are classified. It may also diminish the impact resistance of lenses (how 'shatterproof' the lens is). Revision of standards is needed to test sunglasses quality and establish safe limits for the lenses' UV filters, according to new research.

Designing ultrasound tools with Lego-like proteins Posted: 25 Aug 2016 02:23 PM PDT Ultrasound imaging is used around the world to help visualize developing babies and diagnose diseases. Sound waves bounce off the tissues, revealing their different densities and shapes. The next step in ultrasound technology is to image not just anatomy, but specific cells and molecules deeper in the body, such as those associated with tumors or bacteria in our gut. Now scientists say that [rotein engineering techniques might one day lead to colorful ultrasound images of cells deep within our bodies.

Neuroscientists stand up for basic cell biology research Posted: 25 Aug 2016 02:23 PM PDT Clinical trials and translational medicine have certainly given people hope and rapid pathways to cures for some of humankind's most troublesome diseases, but now is not the time to overlook the power of basic research, says a neuroscientist.

Symmetry crucial for building key biomaterial collagen in the lab Posted: 25 Aug 2016 02:23 PM PDT Functional human collagen has been impossible to create in the lab. Now, a team of researchers describes what may be the key to growing functional, natural collagen fibers outside of the body: symmetry.

In sub-Saharan Africa, cancer can be an infectious disease Posted: 25 Aug 2016 02:23 PM PDT In a new report, a researcher shows that mothers who contract malaria during pregnancy may have children with increased risk of Burkitt's lymphoma.

Fused genes found in esophageal cancer cells offer new clues on disease mechanisms Posted: 25 Aug 2016 02:23 PM PDT Scientists have characterized structurally abnormal genes in esophageal adenocarcinoma, the findings of which could pave way for developing new biomarkers in this fatal disease, they say.

Solving a 48 year old mystery: Scientists grow noroviruses in human intestinal cell cultures Posted: 25 Aug 2016 02:22 PM PDT For the first time, scientists have grown human noroviruses, the leading viral cause of acute diarrhea worldwide, in human intestinal cell cultures in the lab.

New diagnostic instrument sees deeper into the ear Posted: 25 Aug 2016 01:20 PM PDT A new device could greatly improve ear infection diagnoses and drastically reduce unnecessary antibiotic prescriptions, a major cause of antibiotic resistance.

Researchers find roots of modern humane treatment Posted: 25 Aug 2016 01:20 PM PDT Researchers have traced the roots of humane medical practices to a pioneering French physician who treated people with deformities as humans instead of 'monsters,' as they were commonly called.

Manufacturing pharmaceutical and other valuable chemicals: Better decisions Posted: 25 Aug 2016 12:20 PM PDT A new decision-making tool helps producers of pharmaceutical and other valuable chemicals make the leap to an entirely new way of manufacturing.

New study finds low transfer rates of pediatric burn patients in the United States Posted: 25 Aug 2016 12:19 PM PDT Nearly 127,000 kids in the U.S had burn injuries in 2012, research shows. Over half or 69,000 of these children had burns that are considered significant injuries by the American Burn Association.

Finally, the brain sensor that turns down the heat Posted: 25 Aug 2016 12:16 PM PDT At long last, researchers have zeroed in on the neurons that act as the brain's internal thermostat.

Vouchers help get health goods to those most in need Posted: 25 Aug 2016 12:16 PM PDT Distributing health products through a simple voucher system is effective for screening out people who would otherwise accept but not use the free product, a study conducted in Kenya reports.

Factors that might attract children to marijuana edibles Posted: 25 Aug 2016 11:19 AM PDT A new report identifies factors that make food attractive to children. Commissioned by the state Liquor and Cannabis Board, the report studied research on what makes food appeal to children and the role that marketing and branding play.

Fracking chemicals exposure may harm fertility in female mice Posted: 25 Aug 2016 11:17 AM PDT Prenatal exposure to chemicals used in hydraulic fracturing, or fracking, may threaten fertility in female mice, according to a new study.

Children with food allergies predisposed to asthma, rhinitis Posted: 25 Aug 2016 10:09 AM PDT Children with a history of food allergy have a high risk of developing asthma and allergic rhinitis during childhood as well. The risk increases with the number of food allergies a child might have. Research suggests that rates of the common conditions asthma, allergic rhinitis and eczema may be changing in the US.

Researchers find new role for cannabinoids in vision Posted: 25 Aug 2016 10:06 AM PDT A multidisciplinary team of researchers has improved our understanding of how cannabinoids, the active agent in marijuana, affect vision in vertebrates.

Successful recycling: Protein quality control in the cell Posted: 25 Aug 2016 10:06 AM PDT A team of researchers has pinpointed the efficient mechanism used by cells to label faulty proteins. The findings provide important insights into the functioning of protein quality control in the cell.

Risk of adolescents being overweight impacted by neighborhood education, income levels Posted: 25 Aug 2016 10:06 AM PDT A new study found an increased risk for becoming overweight or obese among normal-weight 18-year-olds who lived in neighborhoods with lower education or income levels. The study found that over a four-year period, 25 percent of these young adults became overweight or obese.

Hormone activation of genes takes teamwork Posted: 25 Aug 2016 10:06 AM PDT A high-throughput look at how human cells respond to the stress hormone cortisol has revealed a more complex system than previously thought. The study found that when the cortisol-binding glucocorticoid receptor latches on to DNA to signal a stress response, it binds not alone but in clusters of sites that work together to tune the response. Those clusters then allow the stress hormone to drive a wider variety of stress responses than previously realized.

New research reveals cancers need a 'perfect storm' of conditions to develop Posted: 25 Aug 2016 10:05 AM PDT Scientists have demonstrated for the first time the 'perfect storm' of conditions that cells need to start forming cancer, helping to explain why some organs are more susceptible to developing the disease.

How PSD forms and why defects can cause autism Posted: 25 Aug 2016 10:04 AM PDT Scientists have discovered that SynGAP and PSD-95, two abundance proteins in PSD that are known to cause autism when mutated, can form an autonomously assembled network structure both in test-tube and in living cells. The SynGAP/PSD-95 assembly can form stable 'oil-like' droplets in the midst of aqueous cytoplasm of living cells via phase-transition. This finding provides a possible answer for PSD formation in the field of brain science.

Insights on lung micro-environment explain why cancer spreads to the lungs Posted: 25 Aug 2016 10:04 AM PDT The same mechanisms that that prevent people from having an inflammatory response to harmless environmental exposures in day-to-day life could also all allow rogue cancer cells to spread to the lungs, according to new research. Researchers have discovered and described how the lung's unique underlying immune environment enables cancer to readily spread to the organ.

Men perceived as younger, more attractive after hair transplant for baldness Posted: 25 Aug 2016 10:04 AM PDT Does how much hair a man has matter in how he is perceived? The answer is yes, according to a new article, and this reality can play a role in workplace and social success, say the authors of a new report.

Study examines financial conflict of interests among NCCN guideline authors Posted: 25 Aug 2016 10:04 AM PDT A new study quantifies industry financial conflicts of interest (FCOIs) among authors of National Comprehensive Cancer Network (NCCN) guidelines, work that influences practice and defines drugs reimbursable by Medicare.

Oxygen can impair cancer immunotherapy in mice Posted: 25 Aug 2016 10:04 AM PDT Researchers have identified a mechanism in mice by which anticancer immune responses are inhibited within the lungs, a common site of metastasis for many cancers.

Study shows protein complex essential to creating healthy blood cells Posted: 25 Aug 2016 10:04 AM PDT A group of proteins best known for helping to activate all mammalian genes has been found to play a particularly commanding role in the natural development of specialized stem cells into healthy blood cells, a process known as hematopoiesis.

Calorie-burning 'good' fat can be protected Posted: 25 Aug 2016 10:00 AM PDT Preventing cells of beige fat -- a calorie-burning tissue that can help to ward off obesity and diabetes -- from digesting their own mitochondria traps them in a beneficial, energy-burning state. In mice, this successfully protected against obesity and pre-diabetic symptoms, raising hopes for future applications in human patients.

Scientists discover structural clues to calcium regulation in cells Posted: 25 Aug 2016 10:00 AM PDT The process of energy generation by mitochondria is closely tied to intracellular calcium regulation by a membrane gateway inside mitochondria known as the mitochondrial Ca2+ uniporter (MCU). How MCU regulates calcium uptake has been unclear, but the recent structural discovery of a key MCU domain points toward the involvement of two ions -- calcium and magnesium -- opening new paths to the development of MCU-modulating agents for the treatment of diseases involving mitochondrial dysfunction.

You are subscribed to email updates from Health & Medicine News -- ScienceDaily. To stop receiving these emails, you may unsubscribe now.	Email delivery powered by Google
Google Inc., 1600 Amphitheatre Parkway, Mountain View, CA 94043, United States