ScienceDaily: Health & Medicine News

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• High cholesterol triggers mitochondrial oxidative stress leading to osteoarthritis
• New formulation of ibuprofen may be superior for pain relief than the current version
• Soy protein early in life may help prevent bone loss in adulthood
• Cocoa compound linked to some cardiovascular biomarker improvements
• New molecule may help fight obesity by converting 'bad' fat to 'good' fat
• Early detection method hopes to prevent psychosis
• Two distinct genetic subtypes found in Crohn's disease patients
• Imaging with new biomarker tracks tumor progression, response to treatment for common brain cancer
• Coronary artery disease tests prompt patients toward healthier habits
• Rise in obese pregnant women takes its toll on mother, child both
• Faster, better healing of infected wounds using negative pressure technique
• Small dietary changes reduces cardiovascular disease risk by more than a quarter
• Fungal infection that could help understand some allergies
• Low cost method for examining single leukemia cells could transform treatment
• New study links neuropilin 2 deficiency to inflammation-induced edema and lymphedema
• Changes in depression symptoms tied to lung cancer survival
• Alabama suburban parents drive distracted with children in the car
• Factors secreted by gut bacteria may help combat kidney stones
• Diagnostic tests for sinus infections leave much to be desired, study says
• New candidate vaccines against the plague
• Common prostate cancer treatment linked to later dementia, researcher says
• Untangling a cause of memory loss in neurodegenerative diseases
• Researchers probing the beneficial secrets in dolphins' proteins
• Teens light up cigarettes to slim down
• In the fight against Alzheimer's, online gamers can now get in on the action

High cholesterol triggers mitochondrial oxidative stress leading to osteoarthritis Posted: 14 Oct 2016 12:18 PM PDT High cholesterol might harm more than our cardiovascular systems. New research using animal models suggests that high cholesterol levels trigger mitochondrial oxidative stress on cartilage cells, causing them to die, and ultimately leading to the development of osteoarthritis.

New formulation of ibuprofen may be superior for pain relief than the current version Posted: 14 Oct 2016 12:15 PM PDT Move over aspirin, a new formulation of ibuprofen might prove to be a "wonder drug." Scientists used mice and rats to show that ibuprofen arginate may allow people to take higher doses without the cardiovascular side effects that are associated with current formulations found in over the counter products. In addition to being better tolerated, ibuprofen arginate also is released into the bloodstream more rapidly than the current formulations, likely providing faster pain relief.

Soy protein early in life may help prevent bone loss in adulthood Posted: 14 Oct 2016 12:12 PM PDT Move over milk, soy protein early in life might be what's needed for strong, healthy bones in adulthood. New research reports that early dietary nutrition heavy in soy protein isolate can protect against serious bone loss during adulthood. This also is the first time that scientists have used an animal model to show concrete evidence of a protective effect of an early-life soy protein isolate diet on adult bone loss.

Cocoa compound linked to some cardiovascular biomarker improvements Posted: 14 Oct 2016 12:12 PM PDT To the tantalizing delight of chocolate lovers everywhere, a number of recent studies employing various methods have suggested that compounds in cocoa called flavanols could benefit cardiovascular health. Now a systematic review and meta-analysis of 19 randomized controlled trials (RCTs) of cocoa consumption reveals some further pieces of supporting evidence.

New molecule may help fight obesity by converting 'bad' fat to 'good' fat Posted: 14 Oct 2016 12:10 PM PDT New research suggests that activation of a chemical called Beta-LGND2 by the estrogen receptor Beta (ER-Beta) reduces obesity and metabolic diseases in mice by converting bad fat (white fat) to good fat (brown fat). This is significant as brown fat increases metabolism and may facilitate weight loss.

Early detection method hopes to prevent psychosis Posted: 14 Oct 2016 10:54 AM PDT Mental health researchers have made a promising breakthrough in the early detection of the risk of psychosis, with the eventual hope that patients could be given appropriate treatments earlier to prevent psychotic episodes from occurring.

Two distinct genetic subtypes found in Crohn's disease patients Posted: 14 Oct 2016 10:53 AM PDT Crohn's disease can have devastating consequences and is notoriously hard to treat. Now, scientists have made a discovery that could explain why Crohn's is so variable: the disease has at least two distinct subtypes, each with its own pattern of gene expression and mix of clinical features.

Imaging with new biomarker tracks tumor progression, response to treatment for common brain cancer Posted: 14 Oct 2016 07:32 AM PDT Researchers have developed an MRI-based method that can track the state and progression of a common type of genetically mutated brain cancer.

Coronary artery disease tests prompt patients toward healthier habits Posted: 14 Oct 2016 07:32 AM PDT Undergoing a computer tomographic angiography was a better motivator to get people with suspected coronary artery disease to adopt healthier lifestyle practices than an exercise electrocardiography and stress test, new research shows.

Rise in obese pregnant women takes its toll on mother, child both Posted: 14 Oct 2016 07:32 AM PDT A medical doctor warns that the obesity epidemic is leading to a rise in high-risk pregnancies. There are no standard guidelines for the management of obesity in pregnancy. The American College of Obstetricians and Gynecologists recommends that all pregnant women follow a healthy diet, and consider at least half an hour of moderate physical activity per day during pregnancy. But obese pregnant women represent a relatively new high-risk population that will call for the development of additional tools to help these women reduce these risks before, during and after pregnancy, says this physician.

Faster, better healing of infected wounds using negative pressure technique Posted: 14 Oct 2016 07:26 AM PDT Shorter wound healing time, fewer dressing changes and the opportunity for earlier discharge from the hospital. These are some of the benefits of negative pressure wound therapy to treat wound infections in connection with vascular surgery at the groin. The method, which has become increasingly common, is also cost-effective, a new report shows.

Small dietary changes reduces cardiovascular disease risk by more than a quarter Posted: 14 Oct 2016 07:18 AM PDT Exchanging few commercially regular-consumed food items with improved fat quality reduces total and LDL cholesterol. A new double-blind randomized controlled trial suggests almost 30% reduction in cardiovascular disease risk

Fungal infection that could help understand some allergies Posted: 14 Oct 2016 07:18 AM PDT Researchers reveal how mould from humidity caused by rotting fruits and vegetables unfolds a surprising strategy to infect plants.

Low cost method for examining single leukemia cells could transform treatment Posted: 14 Oct 2016 06:21 AM PDT Leukemia is a disease in which each cell can exhibit different genetic traits, and now researchers have found a cheap way to examine the individual cells. The breakthrough could transform leukemia treatment, say scientists.

New study links neuropilin 2 deficiency to inflammation-induced edema and lymphedema Posted: 14 Oct 2016 06:21 AM PDT Unexpected massive, persistent fluid accumulation and fewer lymphatic capillaries lead to formulation of new hypothesis, according to a new report.

Changes in depression symptoms tied to lung cancer survival Posted: 13 Oct 2016 07:06 PM PDT Worsening depression symptoms are associated with shorter survival for lung cancer patients, particularly those in the early stages of disease, according to a new study.

Alabama suburban parents drive distracted with children in the car Posted: 13 Oct 2016 07:06 PM PDT Parents' driving distracted is a significant danger, and a new study suggests suburban and rural parents still use cellphones with children in the car.

Factors secreted by gut bacteria may help combat kidney stones Posted: 13 Oct 2016 07:05 PM PDT Factors secreted by Oxalobacter formigenes, a bacterium that lives in the large intestine, can reduce urinary excretion of oxalate in mice. Such factors may therefore help prevent or treat kidney stones, say researchers.

Diagnostic tests for sinus infections leave much to be desired, study says Posted: 13 Oct 2016 01:05 PM PDT Many patients who see physicians for sinus infections expect to be prescribed an antibiotic, but for the majority of them, that course of treatment won't be effective. Unfortunately, there aren't great tools to determine which patients will or won't benefit from antibiotics.

New candidate vaccines against the plague Posted: 13 Oct 2016 12:31 PM PDT New potential vaccines have been developed that protect animals against the bacteria that causes the deadly plague. The plague of Black Death infamy has had the power to strike fear in people since the Middle Ages -- and for good reason. Once someone begins to show symptoms, the disease progresses very quickly and is almost 100 percent fatal without prompt treatment. The World Health Organization has categorized the bacteria responsible for plague, Yersinia pestis, as a re-emerging pathogen because of the rising number of human plague cases globally.

Common prostate cancer treatment linked to later dementia, researcher says Posted: 13 Oct 2016 12:30 PM PDT Men with prostate cancer who are treated with testosterone-lowering drugs are twice as likely to develop dementia within five years as prostate cancer patients whose testosterone levels are not tampered with, research shows.

Untangling a cause of memory loss in neurodegenerative diseases Posted: 13 Oct 2016 12:03 PM PDT Tauopathies are a group of neurodegenerative disorders, including Alzheimer's disease that are characterized by the deposition of aggregates of the tau protein inside brain cells. A new study reveals that the cutting of tau by an enzyme called caspase-2 may play a critical role in the disordered brain circuit function that occurs in these diseases. Of interest, the culprit tau fragment identified in this study is actually resistant to forming aggregates, and it causes a disturbance in memory function in animal models before brain cell loss occurs.

Researchers probing the beneficial secrets in dolphins' proteins Posted: 13 Oct 2016 11:56 AM PDT Why reinvent the wheel when nature has the answer? One researcher's natural inspiration is coming from dolphins who seem to have protective proteins that may contain clues to treatments for aging-associated diseases in humans. A recent study has found that dolphin serum contains very high levels of an antioxidant protein.

Teens light up cigarettes to slim down Posted: 13 Oct 2016 11:55 AM PDT Many doctors and public health experts assume that people smoke cigarettes simply because they're addicted to the nicotine. But a group of researchers has found that overweight and obese teens light up for a different reason: to lose weight.

In the fight against Alzheimer's, online gamers can now get in on the action Posted: 12 Oct 2016 09:12 AM PDT Researchers behind a new online game are inviting members of the public to look under a virtual microscope and contribute directly to Alzheimer's disease research.

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