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- Fat fuels the road to cancer cell spread
- Nanodiscs deliver personalized cancer therapy to immune system
- Engineers create programmable silk-based materials with embedded, pre-designed functions
- Synthetic stem cells could offer therapeutic benefits, reduced risks
- Research reveals the importance of long non-coding RNA regulating cellular processes
- Experimental therapy for Prader-Willi syndrome shows promise in mice
- Naturally occurring mechanism of cancer drug-resistance may itself be a treatment target
- Dental implants with antibacterial activity and designed to facilitate integration into the bone
- Novel drug may help repair failing hearts
Fat fuels the road to cancer cell spread Posted: 26 Dec 2016 06:13 PM PST Cancer cells spread to other sites in the body through promoting the growth of new 'roads' to travel on. Scientists have discovered how a shift to increased fat utilization is required for the development and growth of these 'roads,' termed lymphatic vessels -- a special kind of blood vessels. |
Nanodiscs deliver personalized cancer therapy to immune system Posted: 26 Dec 2016 06:12 PM PST Researchers have had initial success in mice using nanodiscs to deliver a customized therapeutic vaccine for the treatment of colon and melanoma cancer tumors. |
Engineers create programmable silk-based materials with embedded, pre-designed functions Posted: 26 Dec 2016 06:12 PM PST Engineers have created a new format of solids made from silk protein that can be preprogrammed with biological, chemical, or optical functions, such as mechanical components that change color with strain, deliver drugs, or respond to light. |
Synthetic stem cells could offer therapeutic benefits, reduced risks Posted: 26 Dec 2016 06:12 PM PST Researchers have developed a synthetic version of a cardiac stem cell. These synthetic stem cells offer therapeutic benefits comparable to those from natural stem cells and could reduce some of the risks associated with stem cell therapies. Additionally, these cells have better preservation stability and the technology is generalizable to other types of stem cells. |
Research reveals the importance of long non-coding RNA regulating cellular processes Posted: 26 Dec 2016 06:12 PM PST Scientific research over the past decade has concentrated almost exclusively on the 2 percent of the genome's protein coding regions, virtually ignoring the other 98 percent. Investigators now reveal that long non-coding RNA (lncRNA) may be critically important for controlling cellular components in a tissue-specific manner, with new research pointing to an lncRNA's key role in helping control processes related to muscle regeneration and cancer. |
Experimental therapy for Prader-Willi syndrome shows promise in mice Posted: 26 Dec 2016 06:12 PM PST Drugs capable of activating silenced genes improve survival and growth outcomes in a mouse model of Prader-Willi syndrome (PWS), a rare and incurable childhood disease. |
Naturally occurring mechanism of cancer drug-resistance may itself be a treatment target Posted: 26 Dec 2016 06:09 PM PST The use of proteasome inhibitors to treat cancer has been greatly limited by the ability of cancer cells to develop resistance to these drugs. But researchers have found a mechanism underlying this resistance -- a mechanism that naturally occurs in many diverse cancer types and that may expose vulnerabilities to drugs that spur the natural cell-death process. |
Dental implants with antibacterial activity and designed to facilitate integration into the bone Posted: 26 Dec 2016 02:53 PM PST Scientists are developing coatings for dental implants to help ensure successful implantation. |
Novel drug may help repair failing hearts Posted: 26 Dec 2016 02:53 PM PST Cimaglermin, a new experimental drug, may help restore cardiac function after heart failure, according to a first-in-man study. |
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