ScienceDaily: Health & Medicine News

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• New study analyzes barriers to cancer research commercialization
• New multiple action intestinal hormone corrects diabetes
• Atherosclerosis in HIV patients linked to infection, not treatment
• Incurable brain cancer gene silenced: Gene regulation technology increases survival rates in mice with glioblastoma
• Two peptides better than one in targeting diabetes, obesity
• Chinese bats likely source of SARS virus
• Pore formation in cell membranes linked to triggers of rheumatoid arthritis
• Researchers study epigenetic mechanisms of tumor metastasis for improved cancer therapy
• Lowering blood pressure prevents cardiovascular events in people with kidney disease
• Potential window for treating CMV, preventing mother-to-child transmission
• MS study correlates negative effect of warmer weather on cognitive status
• Divorced people more likely to die from preventable accidents
• Pain in infancy alters response to stress, anxiety later in life
• Nerve stimulation in neck may reduce heart failure symptoms
• Prices, family interactions influence eating behaviors
• Bloomberg's health legacy: Urban innovator or meddling nanny?
• First aid teams set to improve heart attack survival with pocket manual
• Media Consumption To Average 15.5 Hours A Day By 2015
• Alarming increase of myopia; environmental factors influence development, progression of myopia
• Baking blueberries changes their polyphenol content, health benefits
• Low vitamin D levels during pregnancy associated with preterm birth for non-white mothers
• A mimic of 'good cholesterol' could treat cardiovascular, other diseases
• First health economic evaluation of antidepressants completed
• 'Good' cholesterol controls blood glucose
• Weight loss not always beneficial for romantic relationships
• Events coordination during embryogenesis
• Stents linked to low major adverse coronary events
• Biomarkers could lead to early diagnosis of colorectal cancer
• New look at old test may provide earlier detection of meningitis
• Study explores intimate partner violence across generations
• Is left-handedness higher among those suffering from psychosis?
• New substance effectively combats multi-resistant bacteria
• Qigong can help fight fatigue in prostate cancer survivors
• Type 2 diabetes: New associations identified between genes, metabolic markers
• RNA build-up linked to dementia, motor neuron disease
• Those with Alzheimer's more likely to have heart disease , offered less treatment options
• Scientist identify genetic link between language impairment, autism
• Face it: Twins who smoke look older
• Re-examination of JFK assassination medical data reviews single shooter versus conspiracy theories
• 'Gravity theory' may explain male pattern baldness
• Negative consequences of noise on overall health
• Teenagers, young adults diagnosed with cancer at increased risk of suicide
• Exercise programs could help to prevent fall injuries in elderly
• Unpublished trial data 'violates an ethical obligation' to study participants, say researchers
• Knowledge about incontinence, pelvic organ prolapse lower among women of color
• Dinner rituals correlate with child, adult weight
• Mechanisms of wound healing clarified in zebrafish study
• New molecular target for malaria control identified
• Staying one step ahead of influenza
• How poverty molds the brain: Poor neural processing of sound linked to lower maternal education background
• Older children with HIV may need to start treatment sooner than thought
• Interventions by non-mental health specialists may improve perinatal mental health disorders
• Women benefit from less-used wrist access site for angioplasty
• News that is better or worse than expected influences health decisions
• Researchers identify way to increase gene therapy success
• Quality of care improves for cancer patients who get palliative care consultation
• Weight at time of diagnosis linked to prostate cancer mortality
• Sedentary behavior linked to recurrence of precancerous colorectal tumors
• Estrogen protects women with NASH from severe liver fibrosis
• Experimental drug shows promise in lung cancer

New study analyzes barriers to cancer research commercialization Posted: 30 Oct 2013 03:54 PM PDT A new study cites a combination of factors that prevent academic-based cancer research faculty from ultimately commercializing their work.

New multiple action intestinal hormone corrects diabetes Posted: 30 Oct 2013 11:29 AM PDT Scientists have developed a new therapeutic approach for treatment of Type 2 diabetes. A novel single molecule hormone, which acts equally on the receptors of the insulin-stimulating hormones GLP-1 and GIP, was observed to reduce weight and improve blood sugar.

Atherosclerosis in HIV patients linked to infection, not treatment Posted: 30 Oct 2013 11:29 AM PDT HIV infection, not antiretroviral therapy (ART), is associated with risk for atherosclerosis in patients with no history of smoking, particularly those infected for eight years or more. While a growing body of literature reports that HIV patients have higher risk for atherosclerotic disease and cardiovascular disease, it had been unknown whether HIV infection or ART are the responsible factors, and to what extent traditional cardiovascular risk factors, chiefly smoking, are responsible.

Incurable brain cancer gene silenced: Gene regulation technology increases survival rates in mice with glioblastoma Posted: 30 Oct 2013 11:28 AM PDT Glioblastoma multiforme, the brain cancer that killed Sen. Edward Kennedy, is aggressive and incurable. Researchers can now demonstrate delivery of a drug that turns off a critical gene in this complex cancer, increasing survival rates significantly in animals with the disease. The therapeutic, based on nanotechnology, is nimble enough to cross the blood-brain barrier and get to the brain tumor. Once there, it flips the switch of the oncogene to "off," silencing the gene.

Two peptides better than one in targeting diabetes, obesity Posted: 30 Oct 2013 11:28 AM PDT Researchers have published results showing that a molecule combining the properties of two endocrine hormones is an effective treatment for adult-onset diabetes. The research included clinical trials with human subjects as well as detailed laboratory studies with rodents and monkeys. The drug candidate targets receptors for two naturally occurring peptide hormones, known as GLP-1 and GIP.

Chinese bats likely source of SARS virus Posted: 30 Oct 2013 11:24 AM PDT Scientists say they've produced "the clearest evidence yet" the SARS virus originated in Chinese horseshoe bats and that direct bat-to-human transmission is "plausible." The 2002 severe acute respiratory syndrome coronavirus (SARS-CoV) pandemic was one of the most significant public health events in recent history and researchers have been studying the virus to better understand how it is transmitted to prepare for future outbreaks.

Pore formation in cell membranes linked to triggers of rheumatoid arthritis Posted: 30 Oct 2013 11:24 AM PDT Experiments by scientists have unraveled two biological mechanisms as the major cause of protein citrullination in rheumatoid arthritis. Protein citrullination is suspected of sparking the immune system and driving the cascade of events leading to the disease.

Researchers study epigenetic mechanisms of tumor metastasis for improved cancer therapy Posted: 30 Oct 2013 10:28 AM PDT A review article by researchers suggests that epigenetics may be a useful target to stop the growth, spread and relapse of cancer.

Lowering blood pressure prevents cardiovascular events in people with kidney disease Posted: 30 Oct 2013 09:56 AM PDT Lowering blood pressure is a highly effective and affordable way to prevent cardiovascular events like heart attack and stroke among people with chronic kidney disease. One in 10 people globally is affected by kidney disease, with many unaware of the problem, which puts them at increased risk of cardiovascular disease as well as kidney failure.

Potential window for treating CMV, preventing mother-to-child transmission Posted: 30 Oct 2013 09:56 AM PDT Using next generation sequencing and population genetic modeling, scientists have found that CMV evolves rapidly and dramatically in humans. These findings provide new genetic targets that could impede the evolution of CMV and prevent its spread.

MS study correlates negative effect of warmer weather on cognitive status Posted: 30 Oct 2013 09:56 AM PDT Scientists correlated fMRI findings with the negative impact of outdoor temperature on cognitive functioning in multiple sclerosis. This study in Brain Imaging & Behavior corroborates the group's previous study that established that people with MS performed worse on cognitive tasks during warmer outdoor temperatures. This new study extends previous research by demonstrating a link between brain activity and outdoor temperature.

Divorced people more likely to die from preventable accidents Posted: 30 Oct 2013 09:55 AM PDT Divorced people are more likely to die from preventable accidents than married counterparts, according to a new study.

Pain in infancy alters response to stress, anxiety later in life Posted: 30 Oct 2013 09:55 AM PDT Early life pain alters neural circuits in the brain that regulate stress, suggesting pain experienced by infants who often do not receive analgesics while undergoing tests and treatment in neonatal intensive care may permanently alter future responses to anxiety, stress and pain in adulthood, medical researchers have discovered.

Nerve stimulation in neck may reduce heart failure symptoms Posted: 30 Oct 2013 09:53 AM PDT A multidisciplinary team of experts in heart failure, cardiac arrhythmia, and neurosurgery are now testing nerve stimulation in the neck as a novel therapy for heart failure patients to potentially help relieve their debilitating symptoms of fatigue, shortness of breath, and heart arrhythmias, while reducing their hospitalizations.

Prices, family interactions influence eating behaviors Posted: 30 Oct 2013 09:53 AM PDT Researchers looked at how prices, parents and peers affect fruit and vegetable consumption among African-American youths. Researchers say understanding these factors can help design more effective policy interventions.

Bloomberg's health legacy: Urban innovator or meddling nanny? Posted: 30 Oct 2013 08:14 AM PDT As New York City Mayor Michael Bloomberg prepares to leave office, a commentary by a leading bioethicist analyzes his controversial public health policies and concludes that he is an urban innovator who created a new paradigm of public health, "reaching beyond infectious diseases to upstream risk factors in everyday life and the human habitat."

First aid teams set to improve heart attack survival with pocket manual Posted: 30 Oct 2013 08:13 AM PDT First aid teams are set to improve the survival of heart attack patients with the first pocket-sized manual on acute cardiac conditions. The toolkit was created to help first aid teams across Europe make the best decisions in seconds after a heart attack.

Media Consumption To Average 15.5 Hours A Day By 2015 Posted: 30 Oct 2013 08:13 AM PDT A new report looks at media consumption by individuals in and out of the home, excluding the workplace, between 2008 and 2015, breaking "media" down into 30 categories of media type and delivery (e.g. television, social media, computer gaming) and conclude that the average person will consume 15.5 hours per day by 2015.

Alarming increase of myopia; environmental factors influence development, progression of myopia Posted: 30 Oct 2013 08:13 AM PDT New research on myopia — how it develops, risk and protective factors, and potentially effective measures for prevention and treatment - is widely available to help address the illness.

Baking blueberries changes their polyphenol content, health benefits Posted: 30 Oct 2013 07:41 AM PDT Blueberries are called a "superfood" for their high polyphenol content, but when served as warm, gooey pie filling or when lending bursts of sweet flavor to a muffin, their "super" health benefits change. Scientists studied how cooking and baking affect the increasingly popular fruit's polyphenols and reported their mixed findings in a new article.

Low vitamin D levels during pregnancy associated with preterm birth for non-white mothers Posted: 30 Oct 2013 07:41 AM PDT African-American and Puerto Rican women who have low levels of vitamin D during pregnancy are more likely to go into labor early and give birth to preterm babies, research reveals. The study is the largest to date to look at the association between vitamin D and preterm birth.

A mimic of 'good cholesterol' could treat cardiovascular, other diseases Posted: 30 Oct 2013 07:41 AM PDT A new type of "good cholesterol," made in the lab, could one day deliver drugs to where they are needed in the body to treat disease or be used in medical imaging, according to scientists. The report states that the high-density lipoprotein mimic is easy to make in large amounts.

First health economic evaluation of antidepressants completed Posted: 30 Oct 2013 07:41 AM PDT The report on a health economic evaluation of antidepressants has provided very helpful results. It is now for politicians to decide what role such health economic evaluations should play in the health care system.

'Good' cholesterol controls blood glucose Posted: 30 Oct 2013 07:36 AM PDT High density lipoprotein cholesterol (HDL), the so-called "good" cholesterol, improves blood glucose levels by enhancing skeletal muscle function and reducing adiposity, scientists report.

Weight loss not always beneficial for romantic relationships Posted: 30 Oct 2013 07:35 AM PDT Losing weight is beneficial for human health, but when one partner in a romantic relationship loses weight, it doesn't always have a positive effect on the relationship. According to new research, there can be a "dark side" to weight loss if both partners are not on board with enacting healthy changes.

Events coordination during embryogenesis Posted: 30 Oct 2013 06:32 AM PDT A new study reveals a mechanism through which the expression of genes is controlled -- a finding that highlights genetic mutations that can impair the timing of gene expression. Such mutations can affect the co-ordination of key events that are required for stepwise development of an organism, and can also give rise to cancer by turning on genes at the wrong time.

Stents linked to low major adverse coronary events Posted: 30 Oct 2013 06:32 AM PDT A new study found that both drug-eluting stents (DES) with biocompatible polymers and DES with biodegradable polymers were associated with low major adverse coronary events, demonstrating the non-inferiority of the biocompatible polymer stents in patients undergoing percutaneous coronary intervention.

Biomarkers could lead to early diagnosis of colorectal cancer Posted: 30 Oct 2013 06:31 AM PDT Diagnosing colorectal cancer is complex; it relies on significant invasive tests and subjective evaluations. This process may soon become much easier thanks to a medical breakthrough. Researchers have identified genetic changes in the colon lining, or mucosa, in colorectal cancer patients that could be used as biomarkers of the disease. That will allow doctors to diagnose patients earlier, more accurately and less invasively.

New look at old test may provide earlier detection of meningitis Posted: 30 Oct 2013 06:31 AM PDT Researchers have found a more accurate method to screen for bacterial meningococcal infection in its early stages, when it's hardest to detect. The method for diagnosis could save lives by getting patients treatment earlier, when the infection is most treatable.

Study explores intimate partner violence across generations Posted: 30 Oct 2013 06:31 AM PDT Most parents who experienced intimate partner violence had children that grew to face violence in their own adult relationships, according to a study published.

Is left-handedness higher among those suffering from psychosis? Posted: 30 Oct 2013 06:31 AM PDT Researchers have long studied the connections between hand dominance and different aspects of the human brain. A new study finds that among those with mental illnesses, left-handers are more likely to suffer from psychotic disorders such as schizophrenia than mood disorders.

New substance effectively combats multi-resistant bacteria Posted: 30 Oct 2013 06:31 AM PDT In Europe alone, more than 25,000 people die each year from infections caused by multi-resistant bacteria. Researchers have now developed and characterized a substance that quickly and effectively kills the virulent bacteria. The substance employs a multifunctional mechanism that reduces the risk of antibiotic resistance.

Qigong can help fight fatigue in prostate cancer survivors Posted: 30 Oct 2013 06:30 AM PDT The flowing movements and meditative exercises of the mind-body activity Qigong may help survivors of prostate cancer to combat fatigue. These are the findings of a trial study that reviewed the severe fatigue that is the most common cancer-related symptom reported by cancer survivors, particularly prostate cancer survivors receiving androgen deprivation therapy.

Type 2 diabetes: New associations identified between genes, metabolic markers Posted: 30 Oct 2013 06:30 AM PDT In two comprehensive studies, scientists discovered new associations of two major type 2 diabetes risk genotypes and altered plasma concentrations of metabolic products. The "Virtual Institute Diabetes" (VID) joint research cooperation is thereby making an important contribution towards explaining the genetic and molecular basis of diabetes.

RNA build-up linked to dementia, motor neuron disease Posted: 30 Oct 2013 06:29 AM PDT A new toxic entity associated with genetically inherited forms of dementia and motor neuron disease has been identified by scientists. The toxin is the result of a genetic mutation that leads to the production of RNA molecules which could be responsible for the diseases.

Those with Alzheimer's more likely to have heart disease , offered less treatment options Posted: 30 Oct 2013 06:29 AM PDT Persons with Alzheimer's disease suffer from ischaemic heart diseases more frequently than others, yet they undergo related procedures and surgery less frequently than persons with no diagnosed AD, according to a nation-wide register-based study. The study involved a total of 28,093 persons; that is every community-dwelling person with a diagnosed Alzheimer's disease living in Finland on 31 December 2005.

Scientist identify genetic link between language impairment, autism Posted: 30 Oct 2013 06:29 AM PDT In the first molecular genetic study of families with a history of both language impairment and autism, scientists may have uncovered a shared origin for the two conditions, an important step toward explaining why some cases of autism are accompanied by language difficulties and others are not. The study indicates that a disorder called specific language impairment — one of the most common developmental delays in children — may be caused by the same genetic variants that lead to language difficulties in some children with autism.

Face it: Twins who smoke look older Posted: 30 Oct 2013 06:29 AM PDT Twins who smoke show more premature facial aging, compared to their nonsmoking identical twins, reports a study.

Re-examination of JFK assassination medical data reviews single shooter versus conspiracy theories Posted: 30 Oct 2013 06:28 AM PDT Fifty years after the assassination of President John F. Kennedy, the medical and scientific evidence may support the possibility of the "single shooter, three bullet theory" of the event. Yet new insights into the old medical data simultaneously suggest there may have been multiple shooters, according to a new article.

'Gravity theory' may explain male pattern baldness Posted: 30 Oct 2013 06:28 AM PDT The effects of gravity may explain the apparently paradoxical effects of testosterone in male pattern baldness, or androgenic alopecia, according to new research.

Negative consequences of noise on overall health Posted: 29 Oct 2013 07:08 PM PDT The combined toll of occupational, recreational and environmental noise exposure poses a serious public health threat going far beyond hearing damage, according to an international team of researchers.

Teenagers, young adults diagnosed with cancer at increased risk of suicide Posted: 29 Oct 2013 07:07 PM PDT Teenagers and young adults are at increased risk of suicide after being diagnosed with cancer according to a study published. A study of nearly eight million Swedes aged 15 and over found that among the 12,669 young people diagnosed with cancer between the age of 15 and 30, there was a 60 percent increased risk of suicide or attempted suicide. The risk was highest (150 percent) in the first year after diagnosis.

Exercise programs could help to prevent fall injuries in elderly Posted: 29 Oct 2013 07:07 PM PDT Exercise programs designed to prevent falls in older adults also appear to prevent injuries caused by falls.

Unpublished trial data 'violates an ethical obligation' to study participants, say researchers Posted: 29 Oct 2013 07:07 PM PDT Almost one in three (29 percent) large clinical trials remain unpublished five years after completion. And of these, 78 percent have no results publicly available, finds a new study.

Knowledge about incontinence, pelvic organ prolapse lower among women of color Posted: 29 Oct 2013 02:19 PM PDT Knowing what symptoms to look for may help women with pelvic floor disorders improve their chances of successful treatment. But knowledge of these disorders is lacking among most women, and especially among women of color, according to a new study.

Dinner rituals correlate with child, adult weight Posted: 29 Oct 2013 02:19 PM PDT Families that eat together without the television on and stay seated until everyone's finished have children with lower weights and body mass index (BMI), reports a study.

Mechanisms of wound healing clarified in zebrafish study Posted: 29 Oct 2013 02:19 PM PDT A crucial component of wound healing in many animals, including humans, is the migration of nearby skin cells toward the center of the wound. How do these neighboring skin cells know which way to migrate? A new paper from scientists clarifies the role of calcium signaling in wound healing.

New molecular target for malaria control identified Posted: 29 Oct 2013 02:18 PM PDT A new study has shown that egg development in the mosquito species primarily responsible for spreading malaria depends on a switch in the female that is turned on by a male hormone delivered during sex. Blocking the activation of this switch could impair the ability of the species, Anopheles gambiae, to reproduce, and may be a viable future strategy for mosquito and malaria control.

Staying one step ahead of influenza Posted: 29 Oct 2013 02:18 PM PDT Every fall, the latest batch of flu vaccines attempts to keep society a step ahead of the evolution of the flu virus. Heroic worldwide surveillance efforts have avoided a repeat of the 1918 flu pandemic, but as shown in the recent H1N1 outbreak, viruses can still outwit even the best public health efforts.

How poverty molds the brain: Poor neural processing of sound linked to lower maternal education background Posted: 29 Oct 2013 02:18 PM PDT Groundbreaking research nearly two decades ago linking a mother's educational background to her children's literacy and cognitive abilities stands out among decades of social science studies demonstrating the adverse effects of poverty. Now new research has taken that finding in a neuroscientific direction: linking poor processing of auditory information in the adolescent brain to a lower maternal educational background.

Older children with HIV may need to start treatment sooner than thought Posted: 29 Oct 2013 02:18 PM PDT Although younger children with HIV are at high risk of disease progression if not treated, new research indicates that they have good potential for achieving high CD4 counts (a measure of a type of white blood cell that correlates with immune function) in later life provided antiretroviral therapy is initiated according to current treatment guidelines.

Interventions by non-mental health specialists may improve perinatal mental health disorders Posted: 29 Oct 2013 02:18 PM PDT In middle-income countries such as China, interventions that have a psychological or social component (often referred to as psychosocial interventions) delivered by health workers who are not mental health specialists could help women during the perinatal period, according to a study published.

Women benefit from less-used wrist access site for angioplasty Posted: 29 Oct 2013 02:16 PM PDT For women who are at high risk of blood loss, using an artery in the wrist may be better than the groin for routing a stent to the heart during coronary angioplasty, according to researchers.

News that is better or worse than expected influences health decisions Posted: 29 Oct 2013 02:16 PM PDT Patients who are unrealistically optimistic about their personal health risks are more likely to take preventive action when confronted with news that is worse than expected, while unrealistic pessimists are less likely to change their behavior after receiving feedback that is better than expected.

Researchers identify way to increase gene therapy success Posted: 29 Oct 2013 02:16 PM PDT Scientists have found a way to overcome one of the biggest obstacles to using viruses to deliver therapeutic genes: how to keep the immune system from neutralizing the virus before it can deliver its genetic payload.

Quality of care improves for cancer patients who get palliative care consultation Posted: 29 Oct 2013 02:16 PM PDT Research now offers compelling evidence that establishing standardized criteria for calling a palliative care consultation improves the quality of care for patients hospitalized with advanced cancer. The investigators saw improvements in the use of hospice services, inpatient mortality, and hospital readmissions among patients offered the intervention.

Weight at time of diagnosis linked to prostate cancer mortality Posted: 29 Oct 2013 11:30 AM PDT Men who are overweight or obese when they are diagnosed with prostate cancer are more likely to die from the disease than men who are of healthy weight, according to a study.

Sedentary behavior linked to recurrence of precancerous colorectal tumors Posted: 29 Oct 2013 11:30 AM PDT Men who spend the most time engaged in sedentary behaviors are at greatest risk for recurrence of colorectal adenomas, benign tumors that are known precursors of colorectal cancers. Although there is extensive evidence supporting an association between higher overall levels of physical activity and reduced risk of colorectal cancer, few studies have focused on the impact of sedentary behavior on colorectal cancer risk.

Estrogen protects women with NASH from severe liver fibrosis Posted: 29 Oct 2013 11:29 AM PDT New research suggests that estrogen protects women with nonalcoholic steatohepatitis from severe liver fibrosis. According to research, men are at higher risk of more severe fibrosis compared to women prior to menopause, but liver fibrosis severity is similar in men and post-menopausal women.

Experimental drug shows promise in lung cancer Posted: 29 Oct 2013 11:28 AM PDT MK-3475, an anti-PD1 immunotherapy drug with promising results in advanced trials in melanoma, is also showing potential in lung cancer based on preliminary phase 1b data. By blocking the PD-1 protein, the drug alerts the immune system to attack the cancer. It is generally well tolerated and further trials in lung cancer are currently underway.

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