الجمعة، 21 يونيو 2013

ScienceDaily: Health & Medicine News

ScienceDaily: Health & Medicine News


Men who can't produce sperm face increased cancer risk

Posted: 20 Jun 2013 06:40 PM PDT

Men who are diagnosed as azoospermic -- infertile because of an absence of sperm in their ejaculate -- are more prone to developing cancer than the general population, urologists have found. And a diagnosis of azoospermia before age 30 carries an eight-fold cancer risk, the study says.

Light and nanoprobes detect early signs of infection

Posted: 20 Jun 2013 01:28 PM PDT

Biomedical engineers and genome researchers have developed a proof-of-principle approach using light to detect infections before patients show symptoms.

Sleep deprivation in teens linked to poor dietary choices

Posted: 20 Jun 2013 01:27 PM PDT

Well-rested teenagers tend to make more healthful food choices than their sleep-deprived peers, according to a new study. The finding may be key to understanding the link between sleep and obesity.

Study on fragile newborns challenges current practices

Posted: 20 Jun 2013 11:29 AM PDT

One of the largest clinical trials done in infants with congenital heart diseases shows that the increasingly common practice of using the drug clopidogrel (Plavix) to reduce shunt-related blood flow issues is not effective in the dose studied.

How a mutated protein outwits evolution and fuels leukemia

Posted: 20 Jun 2013 11:28 AM PDT

Scientists have discovered the survival secret to a genetic mutation that stokes leukemia cells, solving an evolutionary riddle and paving the way to a highly targeted therapy for leukemia. A new article describe how a mutated protein, called Fbxw7, behaves differently when expressed in cancer cells versus healthy cells.

Thirdhand smoke causes DNA damage

Posted: 20 Jun 2013 10:24 AM PDT

A new study has found for the first time that thirdhand smoke -- the noxious residue that clings to virtually all surfaces long after the secondhand smoke from a cigarette has cleared out -- causes significant genetic damage in human cells.

Total amount of exercise important, not frequency, research shows

Posted: 20 Jun 2013 10:24 AM PDT

Getting at least 150 minutes of exercise per week is paramount for health but choosing how to schedule the exercise is not.

Does your salad know what time it is? Managing vegetables' 'internal clocks' postharvest could have health benefits

Posted: 20 Jun 2013 10:23 AM PDT

Biologists have found there may be potential health benefits to storing fresh produce under day-night cycles of light. In a new study researchers used lighting to alter the circadian rhythms of cabbage, lettuce, spinach, zucchini, carrots, sweet potatoes and blueberries. The scientists showed how manipulation of circadian rhythms caused cabbage to produce more phytochemicals, including antioxidants.

The link between circadian rhythms and aging: Gene associated with longevity also regulates the body's circadian clock

Posted: 20 Jun 2013 10:23 AM PDT

Human sleeping and waking patterns are largely governed by an internal circadian clock that corresponds closely with the 24-hour cycle of light and darkness. This circadian clock also controls other body functions, such as metabolism and temperature regulation. A new study finds that a gene associated with longevity also regulates the body's circadian clock.

Two-week treatment found to prevent epilepsy in mice gives hope for drug development

Posted: 20 Jun 2013 10:23 AM PDT

Temporal lobe epilepsy is characterized by recurrent seizures throughout life and often behavioral abnormalities, with devastating impacts on patients and their families. Unfortunately, the condition is often not responsive to anticonvulsants. Now scientists report that targeting a particular signaling pathway in mice can prevent the development of temporal lobe epilepsy with two weeks of treatment, offering hope that researchers will be able to develop effective drugs to mitigate recurrent seizures and the development of epilepsy.

Chlamydia promotes gene mutations

Posted: 20 Jun 2013 10:22 AM PDT

Chlamydia trachomatis is a human pathogen that is the leading cause of bacterial sexually transmitted disease worldwide with more than 90 million new cases of genital infections occurring each year. About 70 percent of women infected with Chlamydiaremain asymptomatic and these bacteria can establish chronic infections for months, or even years. Even when it causes no symptoms, Chlamydia can damage a woman's reproductive organs.

Herding cancer cells to their death

Posted: 20 Jun 2013 10:21 AM PDT

Scientists have developed a therapeutic strategy that manipulates a mechanism driving cellular heterogeneity to treat advanced melanoma.

Key player in the genesis of human intestinal immunity identified

Posted: 20 Jun 2013 10:21 AM PDT

Better treatments for people suffering from compromised intestinal immunity may emerge from a small-animal model of human intestinal immune development.

Key signaling pathway that makes young neurons connect

Posted: 20 Jun 2013 10:21 AM PDT

Neuroscientists have filled in a significant gap in the scientific understanding of how neurons mature, pointing to a better understanding of some developmental brain disorders.

Pluripotent stem cells made from pancreatic cancer cells are first human model of the cancer's progression

Posted: 20 Jun 2013 10:21 AM PDT

Pancreatic cancer carries a dismal prognosis. Researchers and clinicians don't have a non-invasive way to even detect early cells that portent later disease. Scientists have created a research cell line from a patient with advanced pancreatic cancer. This first-of-its-kind human-cell model of pancreatic cancer progression is the first example using induced pluripotent stem cells to model cancer progression directly from a solid tumor and to model pancreatic cancer from early to invasive stages.

Animal study shows promising path to prevent epilepsy

Posted: 20 Jun 2013 10:21 AM PDT

Researchers have identified a receptor in the nervous system that may be key to preventing epilepsy following a prolonged period of seizures. Their findings from studies in mice provide a molecular target for developing drugs to prevent the onset of epilepsy, not just manage the disease's symptoms.

Hospital reduces incidence of hospital-associated C. difficile by 70 percent

Posted: 20 Jun 2013 08:12 AM PDT

Rhode Island Hospital has reduced the incidence of hospital-associated Clostridium difficile (C. difficile) infections by 70 percent and reduced annual associated mortality in patients with hospital-associated C. difficile by 64 percent through successive implementation of five rigorous interventions. A major cause of morbidity and mortality in the US, C. difficile can cause life-threatening infections that occur most frequently in patients who have received antibiotic therapy.

Autophaser improves sample analysis in areas such as cancer, Alzheimer's and oil spills

Posted: 20 Jun 2013 08:12 AM PDT

A new software package allows researchers to vastly improve the performance of one of the key tools used to analyse medical and environmental samples.

Potential drug compound attacks Parkinson's on two fronts

Posted: 20 Jun 2013 08:11 AM PDT

Scientists have found a compound that could counter Parkinson's disease in two ways at once. Scientists now describe a "dual inhibitor" that attacks a pair of proteins closely associated with development of Parkinson's disease.

54% of pregnant women use insecticides that are harmful to the fetus, Spanish study shows

Posted: 20 Jun 2013 07:08 AM PDT

Pregnancy and infancy are the periods of greatest vulnerability to the use of household insecticides. This is one of the findings of the first study of its kind to be carried out in Spain, which concludes that more than half of expectant mothers routinely use these chemical compounds. Spanish researchers have described the use of domestic pesticides during pregnancy and the first year of life in nearly 2,500 women and children.

Lab reproduction of a marine compound with antibiotic properties

Posted: 20 Jun 2013 07:08 AM PDT

Chemists have synthesized baringolin, a substance isolated from the depths of the sea. At very small doses this compound inhibits the growth of antibiotic-resistant bacteria.

Virus combination effective against deadly brain tumor

Posted: 20 Jun 2013 07:07 AM PDT

A combination of the myxoma virus and the immune suppressant rapamycin can kill glioblastoma multiforme, the most common and deadliest malignant brain tumor, according to new research. Researchers says the combination has been shown to infect and kill both brain cancer stem cells and differentiated compartments of glioblastoma multiforme.

Realistic 3-d tumor created through tissue engineering using silk scaffolds

Posted: 20 Jun 2013 04:14 AM PDT

Medical researchers have developed a highly realistic three-dimensional (3-D) tumor model. As it replicates the conditions in the body, it is able to track the effectiveness and progress of drug therapy. Their model has the potential to be a more effective method for studying tumors than in-vitro and even in-vivo methods.

New regulator discovered for information transfer in the brain

Posted: 20 Jun 2013 04:14 AM PDT

The protein mSYD1 has a key function in transmitting information between neurons.

Flu shot likely prevented 13 million illnesses, 110,000 hospitalizations from 2005-2011

Posted: 19 Jun 2013 04:51 PM PDT

Approximately 13 million illnesses and over 110,00 hospitalizations may have been averted by the flu vaccine over the last 6 years in the US, according to new calculations.

One in four stroke patients suffer PTSD

Posted: 19 Jun 2013 04:49 PM PDT

One in four people who survive a stroke or transient ischemic attack (TIA) suffer from symptoms of PTSD within the 1st year post-event, and one in nine experience chronic PTSD more than a year later. The data suggest that each year nearly 300,000 stroke/TIA survivors will develop PTSD symptoms as a result of their health scare.

Restoring appropriate movement to immune cells may save seriously burned patients

Posted: 19 Jun 2013 01:47 PM PDT

Patients who survive the immediate aftermath of major burns are at greatest risk from infections -- particularly the overwhelming, life-threatening immune reaction known as sepsis. A new device measures the movement of key immune cells and may help determine which patients are at greatest risk for infections, and a novel treatment that directly addresses the cause of those complications could prevent many associated deaths.

Why are some college students more likely to 'hook up'?

Posted: 19 Jun 2013 10:25 AM PDT

A new study suggests there are certain factors and behaviors associated with sexual hookups, particularly among first-year college women.

New canary seed is ideal for gluten-free diets in celiac disease

Posted: 19 Jun 2013 10:24 AM PDT

A new variety of canary seeds bred specifically for human consumption qualifies as a gluten-free cereal that would be ideal for people with celiac disease, scientists have confirmed.

Genetic 'off switch' linked to increased risk factors for heart disease

Posted: 19 Jun 2013 10:24 AM PDT

Risk of heart and blood vessel disease may increase when a particular gene is switched off, according to preliminary research.

Sports concussions debate: Does CTE really exist?

Posted: 19 Jun 2013 10:23 AM PDT

Sports concussions are said to cause chronic traumatic encephalopathy, which causes depression, aggression, dementia, etc. But some researchers debate this.

Genetic variants predicting aggressive prostate cancers identified

Posted: 19 Jun 2013 09:20 AM PDT

Researchers have developed a method for identifying aggressive prostate cancers that require immediate therapy. It relies on understanding the genetic interaction between single nucleotide polymorphisms (SNPs). The goal is to better predict a prostate cancer's aggressiveness to avoid unnecessary radical treatment.

Research shows moves to ban pay-to-delay deals are justified

Posted: 19 Jun 2013 07:16 AM PDT

Controversial deals that delay generic versions of drugs coming onto the market can lead to consumers paying significantly more for some treatments, according to new research.

Key protein is linked to circadian clocks, helps regulate metabolism

Posted: 19 Jun 2013 07:16 AM PDT

Inside each of us is our own internal timing device. It drives everything from sleep cycles to metabolism, but the inner-workings of this so-called "circadian clock" are complex, its molecular processes having long eluded scientists. But now, researchers have discovered how one protein regulates fundamental circadian processes -- and how disrupting its normal function can throw this critical system out of sync.

Twice weekly iron supplementation to pregnant women as effective as a daily regime

Posted: 19 Jun 2013 07:16 AM PDT

Daily supplementation of iron tablets to pregnant women does not provide any benefits in birth weight or improved infant growth compared to twice weekly supplementation, according to a new study.

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