ScienceDaily: Health & Medicine News

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• Some deadly breast cancers share genetic features with ovarian tumors
• Researchers solve puzzle of B-cell lymphoma development
• Cancer research yields unexpected new way to produce nylon
• Genomic similarities between breast cancer and ovarian cancers revealed; Findings could aid new treatments
• Cancer genome analysis of breast cancer: Team identifies genetic causes and similarity to ovarian cancer
• New chemistry technique reproduces nature's elusive complexity
• Disparities exist in surgical management of thyroid cancer
• Novel sequencing tools to play important role in understanding form of papillary thyroid cancer
• New mouse model may provide insights into rare genetic syndrome
• Screening for specific genetic mutations with fine needle aspirations could reduce need for thyroid surgery
• Researchers develop editing toolkit for customizing zebrafish genomes

Some deadly breast cancers share genetic features with ovarian tumors Posted: 23 Sep 2012 11:51 AM PDT The most comprehensive analysis yet of breast cancer shows that one of the most deadly subtypes is genetically more similar to ovarian tumors than to other breast cancers. The findings suggest that most basal-like breast tumors and ovarian tumors have similar genetic origins and potentially could be treated with the same drugs.

Researchers solve puzzle of B-cell lymphoma development Posted: 23 Sep 2012 11:51 AM PDT In germinal centers, immune cells learn to fight pathogens with high specificity. Researchers have now identified subpopulations of B cells at the germinal centers which express the proto-oncogene Myc (red). They showed that Myc is essential for the formation and maintenance of germinal centers. Their findings have implications for the pathogenesis of B-cell lymphomas.

Cancer research yields unexpected new way to produce nylon Posted: 23 Sep 2012 11:51 AM PDT In their quest for a cancer cure, researchers made a serendipitous discovery -- a molecule necessary for cheaper and greener ways to produce nylon. The finding arose from an intriguing notion that some of the genetic and chemical changes in cancer tumors might be harnessed for beneficial uses.

Genomic similarities between breast cancer and ovarian cancers revealed; Findings could aid new treatments Posted: 23 Sep 2012 11:50 AM PDT One subtype of breast cancer shares many genetic features with high-grade serous ovarian cancer, a cancer that is very difficult to treat, according to researchers. The findings suggest that the two cancers are of similar molecular origin, which may facilitate the comparison of therapeutic data for subtypes of breast and ovarian cancers.

Cancer genome analysis of breast cancer: Team identifies genetic causes and similarity to ovarian cancer Posted: 23 Sep 2012 11:50 AM PDT A team of scientists with The Cancer Genome Atlas program reports their genetic characterization of 800 breast tumors, including finding some of the genetic causes of the most common forms of breast cancer, providing clues for new therapeutic targets, and identifying a molecular similarity between one sub-type of breast cancer and ovarian cancer.

New chemistry technique reproduces nature's elusive complexity Posted: 23 Sep 2012 11:18 AM PDT Scientists have shown how to synthesize in the laboratory an important set of natural compounds known as terpenes. The largest class of chemicals made by living organisms, terpenes are made within cells by some of the most complex chemical reactions found in biology.

Disparities exist in surgical management of thyroid cancer Posted: 23 Sep 2012 11:12 AM PDT A spectrum of disparities exist in the surgical management of well-differentiated thyroid cancer, according to new data.

Novel sequencing tools to play important role in understanding form of papillary thyroid cancer Posted: 23 Sep 2012 11:12 AM PDT Next-generation sequencing analyses of the follicular variant of papillary thyroid carcinoma may elucidate the biological underpinnings and clinical behavior of an increasingly common disease, according to new data.

New mouse model may provide insights into rare genetic syndrome Posted: 23 Sep 2012 11:12 AM PDT ew mouse models can help scientists study a rare disease, called SECISBP2 syndrome, that causes abnormal thyroid hormone metabolism, delayed bone maturation, as well as other abnormal characteristics that vary by individual, according to new data.

Screening for specific genetic mutations with fine needle aspirations could reduce need for thyroid surgery Posted: 23 Sep 2012 11:12 AM PDT Screening air-dried fine needle aspirations (FNA) for a panel of genetic mutations linked to follicular or papillary thyroid cancer could reduce the need for diagnostic thyroid surgery, according to new data.

Researchers develop editing toolkit for customizing zebrafish genomes Posted: 23 Sep 2012 11:12 AM PDT An international team of scientists has developed a highly-efficient means of editing zebrafish genomes for research purposes, eliminating a bottleneck that has stymied biomedical scientists from using the fish as a model for human disease.

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