ScienceDaily: Health & Medicine News

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• HIV drug shows efficacy in treating mouse models of HER2+ breast cancer, study suggests
• HIV helps explain rise of anal cancer in US males
• Mechanism of opiate addiction is completely different from other drugs
• Tau drug heads into phase 3 trials in frontotemporal dementia, Alzheimer's
• Mice with Lou Gehrig's disease not quite what the doctors ordered
• Scratching the surface: Engineers examine UV effects on skin mechanics
• 'Disgusted' rats teaching scientists about nausea, work may lead to new cancer treatments
• Trauma switch identified: Mechanism protects our brains from turning stress and trauma into post-traumatic stress disorder
• Methadone reduces the risk of HIV transmission, study suggests
• Mosquito genetics may offer clues to control malaria, researchers say
• Diabetes discovery: Two genes increase risk of developing diabetes-associated kidney disease
• Pacemaker could help more heart failure patients
• Experts challenge super food claims: Healthy-giving properties of broccoli, blueberries, may not make it past the gut
• There's no place like home -- For dialysis
• Are inhaled medications effective and safe in critically ill patients on mechanical ventilation?
• Researchers patent a virtual guided-bronchoscopy system to help diagnose lung cancer
• Argentina heart attack death rate nearly halved over 15 years

HIV drug shows efficacy in treating mouse models of HER2+ breast cancer, study suggests Posted: 05 Oct 2012 01:28 PM PDT The HIV protease inhibitor, Nelfinavir, can be used to treat HER2-positive breast cancer in the same capacity and dosage regimen that it is used to treat HIV, according to a new study.

HIV helps explain rise of anal cancer in US males Posted: 05 Oct 2012 01:28 PM PDT The increase in anal cancer incidence in the U.S. between 1980 and 2005 was greatly influenced by HIV infections in males, but not females, according to a new study.

Mechanism of opiate addiction is completely different from other drugs Posted: 05 Oct 2012 10:46 AM PDT Chronic morphine exposure has the opposite effect on the brain compared to cocaine in mice, providing new insight into the basis of opiate addiction, according to researchers. They found that a protein called brain-derived neurotrophic factor, which is increased in cocaine addiction, is inhibited in opioid addiction.

Tau drug heads into phase 3 trials in frontotemporal dementia, Alzheimer's Posted: 05 Oct 2012 10:46 AM PDT A small company with roots in Singapore and Scotland plans to test a relatively unknown compound in clinical trials for a type of dementia that strongly affects behavior.

Mice with Lou Gehrig's disease not quite what the doctors ordered Posted: 05 Oct 2012 10:46 AM PDT You've heard the tale before: Scientists can treat diseases like Alzheimer's and Lou Gehrig's in mice, but when those same drugs get to human trials, they fail. Can researchers come up with mice that better mimic the patient? In the case of Lou Gehrig's, some of the latest mice have a problem: they die not because of their spinal nerve disease, but due to blockage of their gut.

Scratching the surface: Engineers examine UV effects on skin mechanics Posted: 05 Oct 2012 09:39 AM PDT Using mechanical stress testing methods common in materials science, researchers found that UV rays also change the way the outermost skin cells hold together and respond to strain.

'Disgusted' rats teaching scientists about nausea, work may lead to new cancer treatments Posted: 05 Oct 2012 09:38 AM PDT Nausea is a common and distressing side effect of many drugs and treatments. Unlike vomiting, nausea is not well understood, but new research may soon change that. Researchers believe they've found the mechanism in the brain that is responsible for the sensation of nausea -- with the help of some "disgusted" rats.

Trauma switch identified: Mechanism protects our brains from turning stress and trauma into post-traumatic stress disorder Posted: 05 Oct 2012 07:33 AM PDT Researchers have for the first time identified the mechanism that protects us from developing uncontrollable fear.

Methadone reduces the risk of HIV transmission, study suggests Posted: 05 Oct 2012 07:32 AM PDT Methadone reduces the risk of HIV transmission in people who inject drugs.

Mosquito genetics may offer clues to control malaria, researchers say Posted: 05 Oct 2012 07:32 AM PDT An African mosquito species with a deadly capacity to transmit malaria has a perplexing evolutionary history.

Diabetes discovery: Two genes increase risk of developing diabetes-associated kidney disease Posted: 05 Oct 2012 06:29 AM PDT An international group of researchers has discovered two genes that increase the risk of developing diabetes-associated kidney disease.

Pacemaker could help more heart failure patients Posted: 05 Oct 2012 05:25 AM PDT A new study demonstrates that a change in the ECG wave called the QRS prolongation is associated with a higher rate of heart-failure mortality. According to the team that carried out the study the discovery suggests that more heart-failure cases than the most serious could be helped by pacemakers.

Experts challenge super food claims: Healthy-giving properties of broccoli, blueberries, may not make it past the gut Posted: 05 Oct 2012 05:25 AM PDT They have been the mainstay of the health industry for the best part of a decade, but now researchers are using an approach that allows them to delve deeper into the effectiveness of health-promoting 'super foods' and their elixir-giving ilk. While there's no doubt foods such as broccoli, blueberries and whole grains contain polyphenols - compounds that have antioxidant and anti-inflammatory properties - the academic experts contend that little of these health-giving properties actually make it past the gut.

There's no place like home -- For dialysis Posted: 04 Oct 2012 05:10 PM PDT Home hemodialysis could allow patients to enjoy increased freedom, quality of life, greater ability to travel, and tangible health improvements. Increased physician and patient education can eliminate barriers to home hemodialysis and increase its use. Approximately 2 million patients in the world receive some sort of dialysis treatment.

Are inhaled medications effective and safe in critically ill patients on mechanical ventilation? Posted: 04 Oct 2012 10:48 AM PDT Essential medications can be delivered as inhaled drugs to critically ill patients in the ICU who require mechanical ventilation to breathe. Aerosol drug delivery is highly complex, and if not done properly the medication will not reach the lungs and therapy will be ineffective. Researchers have reviewed the efficacy and safety of aerosol delivery of drugs used in the ICU.

Researchers patent a virtual guided-bronchoscopy system to help diagnose lung cancer Posted: 04 Oct 2012 06:31 AM PDT The system guides physicians by describing the best bronchoscope route from the trachea to a peripheral lung lesion. It avoids futile examinations and minimises potential risk for the patient.

Argentina heart attack death rate nearly halved over 15 years Posted: 04 Oct 2012 06:31 AM PDT Mortality caused by myocardial infarction has decreased by 44% over the last 15 years in Argentina, according to new research.

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