ScienceDaily: Health & Medicine News

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• Mapping translation sites in the human genome
• Obese male mice father offspring with higher levels of body fat
• Advances in genetic sequencing diagnose Paralympic hopeful's rare condition
• 'Chase and run' cell movement mechanism explains process of metastasis

Mapping translation sites in the human genome Posted: 16 Jun 2013 12:52 PM PDT Scientists have produced the first genome-wide investigation of cap-independent translation, identifying thousands of mRNA sequences that act as Translation Enhancing Elements, which are RNA sequences upstream of the coding region that help recruit the ribosome to the translation start site.

Obese male mice father offspring with higher levels of body fat Posted: 16 Jun 2013 12:52 PM PDT Male mice who were fed a high-fat diet and became obese were more likely to father offspring who also had higher levels of body fat, a new study finds. The effect was observed primarily in male offspring, despite their consumption of a low-fat diet, scientists reported.

Advances in genetic sequencing diagnose Paralympic hopeful's rare condition Posted: 16 Jun 2013 12:52 PM PDT National Paracycling Champion Tom Staniford has an extremely rare condition which, until now, has puzzled his doctors. He is unable to store fat under his skin -- yet has type 2 diabetes -- and suffered hearing loss as a child. Now, thanks to advances in genome sequencing, an international research team has identified Tom's condition and pinpointed the single genetic mutation that causes it.

'Chase and run' cell movement mechanism explains process of metastasis Posted: 16 Jun 2013 12:50 PM PDT A mechanism that cells use to group together and move around the body -- called 'chase and run' -- has been described for the first time by scientists.

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