ScienceDaily: Health & Medicine News

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• Histone deacetylase 6 inhibition enhances oncolytic viral therapy
• Botox may prevent irregular heartbeat after bypass surgery
• Test catches asthma in children before symptoms appear
• Risk of drug-resistant malaria spreading to Africa
• HIV cure research: Scientists create two-headed protein to deplete HIV reservoir
• Brain connectivity changes with working memory after TBI
• Researchers develop drug delivery technique to bypass blood-brain barrier
• Internal fingerprint sensor peers inside fingertips for more surefire ID
• First synthetic model of a bacterial outer membrane will support antibiotic development
• Dietary fat impacts autoimmune flare-ups in mice
• Stimulating specific brain area could help defrost arms frozen by stroke
• Superbug infection greatest increase in children ages one to five
• Inherent mindfulness linked to lower obesity risk, belly fat
• Later age recommended for first screening mammogram: Now 45 not 40
• New study explains why you bulk up with resistance training, not endurance training
• People with sedentary lifestyles are at increased risk of developing kidney disease
• Bangladesh health successes shift chronic diseases to poor
• New perspective in male infertility: Identification of new molecular target for male contraceptives
• Team-based treatment is better for first episode psychosis
• Alcohol ads linked to teen alcohol brand choices
• First mouse model of spontaneous depression-like episodes shows new candidate brain region
• Healthcare: How stereotypes hurt
• MRI shows heart ages differently in women than in men
• Invention could revolutionize production of future medicine
• Mapping the folding process of a single membrane protein
• New way to fix a broken heart?

Histone deacetylase 6 inhibition enhances oncolytic viral therapy Posted: 20 Oct 2015 04:16 PM PDT Inhibition of histone deaceteylase 6 improves the ability of oncolytic herpes simplex virus type 1 to kill glioma cells, a new study indciates.

Botox may prevent irregular heartbeat after bypass surgery Posted: 20 Oct 2015 04:16 PM PDT Botox injections into fat surrounding the heart reduced the chances of developing an irregular heart rhythm -- the most common complication of bypass surgery -- say scientists.

Test catches asthma in children before symptoms appear Posted: 20 Oct 2015 11:57 AM PDT Nearly 7 million children in the United States have been diagnosed with asthma and thousands more are living undiagnosed, struggling to breathe each day. Now, researchers have found that a commonly used pulmonary lung function test can provide early detection of asthma before a child shows any symptoms of breathing problems. This early diagnosis could reduce the number of people who have serious complications of the disease later in life.

Risk of drug-resistant malaria spreading to Africa Posted: 20 Oct 2015 11:52 AM PDT Drug-resistant forms of Plasmodium falciparum, the deadliest species among malaria parasites, are able to infect the type of mosquito that is the main transmitter of malaria in Africa, according to new findings. The discovery suggests Africa -- where malaria will cause an estimated 400,000 deaths in 2015 -- is more at risk for drug-resistant malaria infections than previously thought, which could further compromise efforts to prevent and eliminate the disease.

HIV cure research: Scientists create two-headed protein to deplete HIV reservoir Posted: 20 Oct 2015 11:52 AM PDT Scientists have created a protein that awakens resting immune cells infected with HIV and facilitates their destruction in laboratory studies. The protein potentially could contribute to a cure for HIV infection by helping deplete the reservoir of long-lived, latently HIV-infected cells that can start making the virus when a person stops taking anti-HIV drugs. Further studies in animals and people are needed to determine the viability of this approach.

Brain connectivity changes with working memory after TBI Posted: 20 Oct 2015 11:52 AM PDT Scientists compared information flow in the brain in traumatic brain injury and controls using neuroimaging and a novel working memory task, CapMan, which measures capacity and mental manipulation. This is the first study to show causal relationship between these tasks of working memory and fronto-parietal regions.

Researchers develop drug delivery technique to bypass blood-brain barrier Posted: 20 Oct 2015 11:52 AM PDT Researchers have successfully prevented the development of Parkinson's disease in a mouse using new techniques to deliver drugs across the naturally impenetrable blood-brain barrier. Their findings lend hope to patients around the world with neurological conditions that are difficult to treat due to a barrier mechanism that prevents approximately 98 percent of drugs from reaching the brain and central nervous system.

Internal fingerprint sensor peers inside fingertips for more surefire ID Posted: 20 Oct 2015 11:52 AM PDT Most optical fingerprint sensors today produce images by reflecting light from areas where the skin does not come in contact with a glass plate, a technique that captures details from only the very top layer of skin. In contrast, a new device images the 'internal fingerprints,' which have the same pattern as external fingerprints, but are about half a millimeter below the skin's surface.

First synthetic model of a bacterial outer membrane will support antibiotic development Posted: 20 Oct 2015 11:48 AM PDT Scientists have developed a model of the outer membrane of the bacteria E. coli (Escherichia coli) providing a brand new tool for developing new antibiotics and other drugs in the fight against infections.

Dietary fat impacts autoimmune flare-ups in mice Posted: 20 Oct 2015 11:48 AM PDT Dietary fat may impact the severity and duration of autoimmune flare-ups, suggests a new study. Adjusting the length of fatty acids consumed by mice altered the function of T helper cells in the gut -- either intensifying or alleviating symptoms in an animal model of the autoimmune disease (i.e., multiple sclerosis).

Stimulating specific brain area could help defrost arms frozen by stroke Posted: 20 Oct 2015 11:48 AM PDT Little can be done to help the hundreds of thousands of people whose severe strokes have left them with one arm stuck close to the sides of their bodies like a broken wing. A 30-patient study, however, has found that magnetically stimulating a specific part of their brains can affect arm movements -- raising hope that, in the future, a short course of therapy targeting this area could help to free the arm and restore some use of the stroke-affected limb.

Superbug infection greatest increase in children ages one to five Posted: 20 Oct 2015 11:09 AM PDT Children are becoming infected with the highly fatal antibiotic resistant bacteria CRE at a much higher rate than the recent past, according to a data analysis in the United States.

Inherent mindfulness linked to lower obesity risk, belly fat Posted: 20 Oct 2015 11:09 AM PDT People with a high degree of attention to their present thoughts and feelings -- 'dispositional mindfulness' -- are less likely to be obese than people with a low degree of dispositional mindfulness, research shows. They also had about a pound less belly fat on average.

Later age recommended for first screening mammogram: Now 45 not 40 Posted: 20 Oct 2015 09:08 AM PDT Among the changes in the American Cancer Society's updated breast cancer screening guideline is that women with an average risk of breast cancer should undergo regular, annual screening mammography beginning at age 45 years, with women having an opportunity to choose to begin annual screening as early as age 40; and women 55 years and older should transition to screening every other year (vs. annual), according to a new article.

New study explains why you bulk up with resistance training, not endurance training Posted: 20 Oct 2015 06:48 AM PDT Resistance and endurance exercises activate the same gene, PGC-1?, but the processes stimulated for the muscles to adapt depend on the exercise type. A new study offers insight into why the physical changes from resistance exercise are so different than from endurance exercise.

People with sedentary lifestyles are at increased risk of developing kidney disease Posted: 20 Oct 2015 06:48 AM PDT Being sedentary for too long during the day may be a risk factor for chronic kidney disease, according to a new study.

Bangladesh health successes shift chronic diseases to poor Posted: 20 Oct 2015 06:18 AM PDT Over the past decades, Bangladesh observed a successful health transition while chronic diseases shifted from the rich to affect, in excess, also poor households. Observations over more than two decades demonstrate that the situation is actually worsening as chronic diseases frequently drag more households below the poverty line. The challenges in health service delivery and financing are huge, say authors of a new report.

New perspective in male infertility: Identification of new molecular target for male contraceptives Posted: 20 Oct 2015 06:16 AM PDT To date, oral contraceptives for women have been developed and used worldwide, but, there are no oral contraceptives for men.

Team-based treatment is better for first episode psychosis Posted: 20 Oct 2015 06:14 AM PDT Treating people with first episode psychosis with a team-based, coordinated specialty care (CSC) approach produces better clinical and functional outcomes than typical community care, new research shows. Investigators also found that treatment is most effective for people who receive care soon after psychotic symptoms begin.

Alcohol ads linked to teen alcohol brand choices Posted: 20 Oct 2015 06:13 AM PDT Overall exposure to brand-specific alcohol advertising is a significant predictor of underage youth alcohol brand consumption, with youth ages 13 to 20 more than five times more likely to consume brands that advertise on national television and 36 percent more likely to consume brands that advertise in national magazines compared to brands that don't advertise in these media.

First mouse model of spontaneous depression-like episodes shows new candidate brain region Posted: 20 Oct 2015 06:13 AM PDT A mouse strain with a mutation that leads to dysfunction of mitochondria -- the 'powerhouses' that provide energy to cells -- spontaneously undergo periodic episodes of depression-like behavior that resemble those in human, scientists report.

Healthcare: How stereotypes hurt Posted: 20 Oct 2015 06:13 AM PDT Warning: Stereotypes may be harmful to patients' health. An American national study has found people who encountered the threat of being judged by negative stereotypes related to weight, age, race, gender, or social class in health care settings were more likely to have hypertension, be depressed, and to rate their own health more poorly. They were also more distrustful of their doctors, felt dissatisfied with their care, and were less likely to use preventive care.

MRI shows heart ages differently in women than in men Posted: 20 Oct 2015 06:13 AM PDT The main pumping chamber of the heart ages differently in men and women, according to a MRI study. Researchers said the findings may support different treatment approaches for men and women with heart disease.

Invention could revolutionize production of future medicine Posted: 19 Oct 2015 09:37 AM PDT A sensor capsule recently developed in Ireland will improve the production of cutting-edge biopharmaceutical treatments for chronic diseases, say experts.

Mapping the folding process of a single membrane protein Posted: 19 Oct 2015 09:31 AM PDT A new method for manipulating the folding of membrane proteins in a membrane environment has been reported by scientists, using a tool called a magnetic tweezer.

New way to fix a broken heart? Posted: 19 Oct 2015 09:29 AM PDT To regenerate a diseased heart, we need to understand how the smooth muscle of artery walls is created. Now scientists have discovered the cell type that could be key.

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