الجمعة، 9 أكتوبر 2015

ScienceDaily: Health & Medicine News

ScienceDaily: Health & Medicine News


Opposites don't attract when learning how to use a prosthesis

Posted: 08 Oct 2015 02:35 PM PDT

Upper limb amputees, who typically struggle to learn how to use a new prosthesis, would be more successful if fellow amputees taught them, new research suggests. Most usually learn by watching a non-amputee demonstrate the device during physical therapy and rehabilitation sessions. A study that measured arm movements and analyzed brain patterns found that people do better when they learn from someone who looks like them.

Smoking, heavy alcohol use are associated with epigenetic signs of aging

Posted: 08 Oct 2015 02:35 PM PDT

Cigarette smoking and heavy alcohol use cause epigenetic changes to DNA that reflect accelerated biological aging in distinct, measurable ways, according to research. The researchers estimated biological age using a previously validated epigenetic "clock" , calculated the difference between biological age and chronological age, and assessed the relationship between tobacco and alcohol use and premature aging.

Menopause diminishes impact of good cholesterol

Posted: 08 Oct 2015 12:28 PM PDT

What has previously been known as good cholesterol -- high density lipoprotein -- has now been shown to be not so good in protecting women against atherosclerosis while they are transitioning through menopause, research shows.

Seeing in a new light

Posted: 08 Oct 2015 12:28 PM PDT

New discoveries at the cellular and molecular levels have been made about how the eye processes light. The findings improve the scientific understanding of the signaling cascade necessary for phototransduction -- the process by which light is converted into electrical signals in the photoreceptor cells in the retina of the eye.

Artificial lung demonstrates how aerosols move and behave in deepest part of lungs

Posted: 08 Oct 2015 11:29 AM PDT

A life-sized artificial human lung is the first diagnostic tool for understanding in real time how tiny particles behave in the deepest part of the human lungs. It could shed light on airborne pollution risks, and be used for the evaluation/design respiratory system drugs.

Surgeons restore hand, arm movement to quadriplegic patients

Posted: 08 Oct 2015 11:27 AM PDT

A pioneering surgical technique has restored some hand and arm movement to patients immobilized by spinal cord injuries in the neck, reports a new study. The researchers assessed outcomes of nerve-transfer surgery in nine quadriplegic patients with spinal cord injuries in the neck. Every patient in the study reported improved hand and arm function.

Environmental memories transmitted from a father to his grandchildren

Posted: 08 Oct 2015 11:26 AM PDT

If you have diabetes, or cancer or even heart problems, maybe you should blame it on your dad's behavior or environment. Or even your grandfather's. That's because, in recent years, scientists have shown that, before his offspring are even conceived, a father's life experiences involving food, drugs, exposure to toxic products and even stress can affect the development and health not only of his children, but even of his grandchildren. But, despite a decade of work in the area, scientists haven't been able to understand much about how this transmission of environmental memories over several generations takes place. Scientists think that they have now found a key part of the molecular puzzle. They have discovered that proteins known as histones, which have attracted relatively little attention until now, may play a crucial role in the process.

Study ties restless legs syndrome to heart, kidney problems

Posted: 08 Oct 2015 11:25 AM PDT

Those with restless legs syndrome are at higher risk for stroke, heart and kidney disease, and earlier death, a database study of Veterans found. Studies in the past had suggested such links, but the new research provides the strongest evidence yet.

EpiPens save lives but can cut like a knife

Posted: 08 Oct 2015 11:24 AM PDT

Epinephrine autoinjectors can be life-saving for patients experiencing anaphylaxis -- a life-threatening emergency -- but according to a new case series, the most commonly used autoinjector appears to be contributing to injuries in children.

One in eight children at risk for measles, analysis shows

Posted: 08 Oct 2015 11:22 AM PDT

Gaps in measles vaccination rates place one in eight children at risk for becoming sick from the highly contagious illness, according to an analysis of American national vaccination coverage.

Scientists build a digital piece of a rat's brain

Posted: 08 Oct 2015 11:22 AM PDT

If you want to learn how something works, one strategy is to take it apart and put it back together again. For 10 years, a global initiative called the Blue Brain Project has been attempting to do this digitally with a section of juvenile rat brain. The project presents a first draft of this reconstruction, which contains over 31,000 neurons, 55 layers of cells, and 207 different neuron subtypes.

Epidural, spinal anesthesia safe for cesarean deliveries, study finds

Posted: 08 Oct 2015 10:12 AM PDT

New research could ease the minds of expectant mothers who may be nervous about epidurals or spinal anesthesia for childbirth. According to ASA practice guidelines, spinal or epidural anesthesia is preferred for most cesarean deliveries. However, general anesthesia may be administered in some cases, such as an emergency cesarean delivery.

Breast cancer genomic analysis reveals invasive lobular carcinoma subtypes

Posted: 08 Oct 2015 10:12 AM PDT

Researchers analyzed hundreds of breast cancer samples to reveal genetic drivers of invasive lobular carcinoma, the second most commonly diagnosed invasive form of breast cancer. The work, the researchers said, could lead to personalized treatment approaches for the disease.

Researchers learn how to grow old brain cells

Posted: 08 Oct 2015 10:12 AM PDT

A new technique allows scientists to study diseases like Alzheimer's and Parkinson's using cells from human patients. Historically, animal models -- from fruit flies to mice -- have been the go-to technique to study the biological consequences of aging, especially in tissues that can't be easily sampled from living humans, like the brain. Over the past few years, researchers have increasingly turned to stem cells to study various diseases in humans.

Antioxidants cause malignant melanoma to metastasize faster

Posted: 08 Oct 2015 10:11 AM PDT

Antioxidants can double the rate of melanoma metastasis in mice, new research shows. The results reinforce previous findings that antioxidants hasten the progression of lung cancer. People with cancer or an elevated risk of developing the disease should avoid nutritional supplements that contain antioxidants, the researchers say.

Study examines cancer-care outcomes among American hospitals

Posted: 08 Oct 2015 10:10 AM PDT

Efforts to rank hospitals by long-term survival rates have been hindered by the readily available administrative data derived from Medicare claims, which lacks information about cancer stage. A new study finds that risk-adjusted Medicare claims data -- without information about the cancer stage of individual patients -- may be sufficient to calculate the long-term survival rates at hospitals providing cancer care in the United States.

Affordable Care Act helps Virginia improve HIV outcomes

Posted: 08 Oct 2015 10:10 AM PDT

Low-income HIV patients enrolled in Affordable Care Act health-care plans achieved better outcomes and the resulting cost savings allowed the state of Virginia to support care for more patients, according to a groundbreaking study.

Why elephants rarely get cancer

Posted: 08 Oct 2015 10:10 AM PDT

A new study could explain why elephants rarely get cancer. The results show that elephants have extra copies of a gene encoding a tumor suppressor, p53. Further, elephants may have a more robust mechanism for killing damaged cells at risk for becoming cancerous. The findings suggest extra p53 could explain elephants' enhanced cancer resistance.

Fracking industry wells associated with premature birth

Posted: 08 Oct 2015 08:05 AM PDT

Expectant mothers who live near active natural gas wells operated by the fracking industry in Pennsylvania are at an increased risk of giving birth prematurely and for having high-risk pregnancies, new research suggests.

Preventing memory loss before symptoms appear

Posted: 08 Oct 2015 08:05 AM PDT

A clinical trial is looking at removing a key protein from the brain to prevent memory loss at least a decade before symptoms are noticed in healthy older adults. The trial is focused on an investigational treatment to reduce the impact of the protein beta amyloid.

Sex change hormonal treatments alter brain chemistry

Posted: 08 Oct 2015 08:05 AM PDT

Hormonal treatments administered as part of the procedures for sex reassignment have well-known and well-documented effects on the secondary sexual characteristics of the adult body, shifting a recipient's physical appearance to that of the opposite sex. New research indicates that these hormonal treatments also alter brain chemistry.

Researchers compare direct gene vs blood cell-mediated therapy of spinal cord injury

Posted: 08 Oct 2015 08:04 AM PDT

Compared with direct gene injection, cell-mediated GDNF gene delivery led to considerably more pronounced preservation of myelinated fibers in the remote segments of the spinal cord (5 vs 3 mm from the epicenter), and this might depend on the expansion of the therapeutic influence in cell-mediated therapy over long distances as a result of the migration of the transplanted cells.

Multilaminar model explains structure of chromosomal aberrations in cancer cells

Posted: 08 Oct 2015 08:04 AM PDT

The organization of DNA packaged in chromosomes during cell division has been very difficult to study experimentally. Researchers have found that the structure of translocations in cancer cells shows that chromosomes are formed by thin plates of chromatin.

'Alarm clock' of a leukemia-causing oncogene identified

Posted: 08 Oct 2015 08:04 AM PDT

Mutations in DNMT3A gene cause MEIS1 activacion, triggering leukemia, a research team demonstrates.

Treatment for rare bleeding disorder is effective, research shows

Posted: 08 Oct 2015 07:14 AM PDT

For the first time, researchers have shown that the relative safety and effectiveness of treatment, eltrombopag, in children with persistent or chronic immune thrombocytopenia (ITP), as part of an international duo of studies. 

Unexpected connections: Calcium refill mechanisms in nerve cells affects gene expression

Posted: 08 Oct 2015 07:13 AM PDT

SOCE (Store Operated Calcium Entry) is a process by which Calcium ions slowly enter cells to refill depleted calcium stores. This process in nerve cells is now thought to play a role in maintaining the levels of dopamine, a vital neurotransmitter in the brains of Drosophila flies. If SOCE operates in a similar way in mammalian neurons, it might provide new pathways to explore the treatment of Parkinson's disease.

Lab-grown 3D intestine regenerates gut lining in dogs

Posted: 08 Oct 2015 06:51 AM PDT

Working with gut stem cells from humans and mice, scientists have successfully grown healthy intestine atop a 3-D scaffold made of a substance used in surgical sutures.

Major flu drug report underway

Posted: 08 Oct 2015 06:49 AM PDT

A new landmark report reveals that anti-viral drugs called NAIs (like Tamiflu) have been successful in reducing deaths in flu patients in hospital. The report also reveals that preventative use of the same drugs helps fight flu infection in the home.

Therapy reduces the risk of fragility fractaures by 40 percent

Posted: 08 Oct 2015 06:49 AM PDT

Osteoporosis, a disease of progressive bone loss, affects 70 percent of the US population older than age 50: one in two women -- and one in five men. These individuals are at risk for fragility fractures, a break that results from a fall, or occurs in the absence of obvious trauma, and most commonly seen in the wrist, the upper arm, the hip, and the spine.

New study shows that varying walking pace burns more calories

Posted: 08 Oct 2015 06:49 AM PDT

Engineering researchers have found that walking at varying speeds can burn up to 20 percent more calories compared to maintaining a steady pace. The study is one of the first to measure the metabolic cost, or calories burned, of changing walking speeds.

Bio-inspired robotic finger looks, feels and works like the real thing

Posted: 08 Oct 2015 05:40 AM PDT

Most robotic parts used to today are rigid, have a limited range of motion and don't really look lifelike. Inspired by both nature and biology, a scientist has designed a novel robotic finger that looks, feels and works like the real thing. Using shape memory alloy, a 3D CAD model of a human finger, a 3D printer and a unique thermal training technique, this robotic finger could ultimately be adapted for use as a prosthetic device, such as on a prosthetic hand.

Protein research uncovers potential new diagnosis, therapy for breast cancer

Posted: 08 Oct 2015 05:40 AM PDT

Scientists, using clinical specimens from charity Breast Cancer Now's Tissue Bank, have conducted new research into a specific sodium channel that indicates the presence of cancer cells and affects tumor growth rates.

Living in fear: Mental disorders as risk factors for chronic pain in teenagers

Posted: 08 Oct 2015 05:39 AM PDT

One in four young people have experienced chronic pain and a mental disorder. According to a new report, the onset of pain is often preceded by mental disorders: an above-average rate of incidence of depression, anxiety disorders, and behavioral disorders occurs before the onset of headaches, back pain and neck pain.

Treating aortic aneurysms through virtual reality

Posted: 08 Oct 2015 05:37 AM PDT

Virtual models can be created in the angiography room thanks to an approach developed by researchers and the university's departments of radiology, radiation oncology, and nuclear medicine.

Up to one billion people at risk of blindness by 2050

Posted: 08 Oct 2015 05:37 AM PDT

5 billion are expected to be myopic (short-sighted) by 2050, scientists say, adding that nearly 1 billion high myopes are at risk of blindness by 2050. Parents are urged to have their children's eyes checked and get them outdoors and moderate time using electronic devices. Governments are called on to fund research and interventions.

Gut microorganisms cause gluten-induced pathology in mouse model of celiac disease

Posted: 08 Oct 2015 05:37 AM PDT

Investigators interested in celiac disease have wondered why only 2 to 5 percent of genetically susceptible individuals develop the disease. Attention has focused on whether environmental determinants, including gut microorganisms, contribute to the development of celiac disease. Using a humanized mouse model of gluten sensitivity, a new study has found that the gut microbiome can play an important role in the body's response to gluten.

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