الثلاثاء، 10 نوفمبر 2015

ScienceDaily: Health & Medicine News

ScienceDaily: Health & Medicine News


Adults born with heart disease at increased risk of heart attack and death

Posted: 09 Nov 2015 03:18 PM PST

A study of adults up to age 70 shows a dramatically increased risk of heart attack in those who were born with heart disease.

Specific vitamin D levels linked to heart problems

Posted: 09 Nov 2015 01:05 PM PST

A lack of vitamin D can result in weak bones. Recent studies also show that vitamin D deficiency is linked to more serious health risks such as coronary artery disease, heart attacks, and strokes.

The art of appropriate patient selection for heart procedures

Posted: 09 Nov 2015 01:02 PM PST

A decline in the number of heart patients undergoing unnecessary PCI (angioplasty) procedures reflects improvements in clinical decision-making and documentation to determine which patients benefit most from the procedure, according to new findings.

Strangled cells condense their DNA

Posted: 09 Nov 2015 12:38 PM PST

Scientists have been able to see, for the first time, the dramatic changes that occur in the DNA of cells that are starved of oxygen and nutrients. This starved state is typical in some of today's most common diseases, particularly heart attacks, stroke and cancer. The findings provide new insight into the damage these diseases cause and may help researchers to discover new ways of treating them.

Genetic risk information for coronary heart disease leads to lower bad cholesterol

Posted: 09 Nov 2015 12:38 PM PST

Medical researchers have discovered that disclosing genetic risk for coronary heart disease, also known as bad cholesterol.

How low to go for blood pressure? Lower target could affect millions of Americans

Posted: 09 Nov 2015 12:31 PM PST

At least 16.8 million Americans could benefit from lowering their systolic blood pressure to 120 mmHg, much lower than current guidelines, according to a new study.

Leading cause of blindness could be prevented or delayed

Posted: 09 Nov 2015 11:24 AM PST

In a major scientific breakthrough, a drug used to treat Parkinson's and related diseases may be able to delay or prevent macular degeneration, the most common form of blindness among older Americans.

Diabetes drug reduces risk of heart failure and may prevent it, study shows

Posted: 09 Nov 2015 11:15 AM PST

For the first time, research shows that a type 2 diabetes drug significantly reduces hospitalizations and death from heart failure. At the end of the trial period, investigators found that patients treated with the drug experienced reductions in blood sugar and blood pressure, as well as weight loss, compared to those on placebo. They also found major significant reductions in hospitalizations for heart failure (35%); the combined result for heart failure hospitalization or dying from heart disease (34%); and the combined result for being hospitalized or dying from heart failure (39%).

Complex grammar of the genomic language

Posted: 09 Nov 2015 11:02 AM PST

The 'grammar' of the human genetic code is more complex than that of even the most intricately constructed spoken languages in the world. The findings explain why the human genome is so difficult to decipher -- and contribute to the further understanding of how genetic differences affect the risk of developing diseases on an individual level.

New genetic cause of a childhood kidney cancer discovered

Posted: 09 Nov 2015 11:01 AM PST

Genetic mutations in a gene called REST have been shown to cause Wilms tumor, a rare kidney cancer that occurs in children.

Molecular clocks control mutation rate in human cells

Posted: 09 Nov 2015 11:01 AM PST

A theory that our cells have molecular clock processes ticking inside them, that damage DNA by generating mutations continuously throughout life, has just been proven.These clock-like mutational processes could ultimately be responsible for a large proportion of human cancer and contribute to human aging. Two clock-like mutational processes have been found in human cells and the rates at which the two clocks tick in different human cell types have been determined.

How glucose regulation enables malignant tumor growth

Posted: 09 Nov 2015 11:01 AM PST

A new study identifies a key pathway used by cancer cells to make the lipids by integrating oncogenic signaling, fuel availability and lipid synthesis to support cell division and rapid tumor growth.

Giant fullerene system inhibits the infection by an artificial Ebola virus

Posted: 09 Nov 2015 11:01 AM PST

Using an artificial Ebola virus model, a medical researchers have demonstrated how a supermolecule -- constituted by 13 fullerenes -- has been able of inhibiting the virus infection by blocking a receptor implied in its expansion. The model, tested in vitro, highlights the potential of this biotechnology to eradicate the infection.

Unpacking embryonic pluripotency

Posted: 09 Nov 2015 10:49 AM PST

Researchers have identified factors that spark the formation of pluripotent cells. Their findings shed light on human embryonic development and help research into cell reprogramming and assisted conception.

Cellular mechanism for transporting calcium in the formation of dental enamel cells

Posted: 09 Nov 2015 10:45 AM PST

The team found that the main calcium influx pathway involved in the mineralization of enamel [called the CRAC (Ca2+ release-activated Ca2+) channel -- the main type of SOCE (Store-operated Ca2+ entry) channel -- is critical for controlling calcium uptake, which is necessary for the development of tooth enamel.

Long-sought protein sensor for the ‘sixth sense’ found -- proprioception

Posted: 09 Nov 2015 10:45 AM PST

For decades, biologists have been trying to find the crucial sensor protein in nerve endings that translates muscle and tendon stretching into proprioceptive nerve signals. Now, scientists have identified this sensor protein in mice.

Flipping the switch to better see cancer cells at depths

Posted: 09 Nov 2015 10:44 AM PST

Using a high-tech imaging method, biomedical engineers were able to see early-developing cancer cells deeper in tissue than ever before with the help of a novel protein from a bacterium.

New enzyme therapy shows proof of concept as treatment for cocaine overdose

Posted: 09 Nov 2015 10:39 AM PST

A long-acting enzyme that rapidly and safely metabolizes cocaine in the blood stream is currently being investigated in animal models as a possible treatment for cocaine overdose.

Long-term effects of wireless heart failure monitor just released

Posted: 09 Nov 2015 08:06 AM PST

Long-term data collected on the use of an FDA-approved wireless heart failure monitor shows the treatment cut hospitalizations nearly in half and significantly reduced risk of death in patients.

Dead bacteria used to kill colorectal cancer

Posted: 09 Nov 2015 08:06 AM PST

Scientists have successfully used dead bacteria to kill colorectal cancer cells.

Exploring the paradox of metabolically healthy obesity

Posted: 09 Nov 2015 08:04 AM PST

Researchers have defined some key characteristics of the metabolically healthy obese -- those obese individuals who remain free from type 2 diabetes and other disorders, that usually associate with obesity. Their findings have implications for the treatment of type 2 diabetes, insulin resistance and obesity.

Poverty influences effects of race and education on pain after knee replacement surgery

Posted: 09 Nov 2015 07:39 AM PST

Findings suggest that lower socioeconomic status at the community level significantly increases the risk of pain and poor function following a knee replacement.

New disease-carrying mosquito arrives in British Columbia, Canada

Posted: 09 Nov 2015 07:39 AM PST

Scientists are studying an invasive, disease-carrying mosquito, Aedes japonicus, after finding it for the first time in Western Canada. The mosquitoes could poise a significant hazard to health if global warming favors the development of some of the viruses it can transmit.

Training for runners: Improve individual skills supported by BigData

Posted: 09 Nov 2015 07:37 AM PST

Running is one of the most popular sports. However, not many runners have received formal training on running. Researchers have developed a system for improving running skills based on big data analysis.

Combination therapy reduces occurrence, number of migraines following cardiac procedure

Posted: 09 Nov 2015 07:37 AM PST

Scientists randomly assigned 171 patients with an indication for atrial septal defect (ASD) closure and no history of migraine to receive dual antiplatelet therapy (aspirin + clopidogrel [the clopidogrel group], n = 84) or single antiplatelet therapy (aspirin + placebo [the placebo group], n = 87) for 3 months following transcatheter ASD closure.

Coronary angioplasties classified as inappropriate reduced since guidelines published

Posted: 09 Nov 2015 07:37 AM PST

Researchers examined trends in percutaneous coronary intervention use, patient selection, and procedural appropriateness following the introduction of Appropriate Use Criteria.

Wealthiest -- not sickest -- patients may have edge in organ transplants

Posted: 09 Nov 2015 07:37 AM PST

Registering at multiple transplant centers appears to give an edge to wealthy organ transplant patients over those with the most medical need. Multiple listing -- more likely done by wealthy, privately insured patients -- is an effective way to address organ shortages, but undermines the principle of transplanting the sickest patients first and should be reconsidered, researchers said.

Temporary ambulance locations reduces response times and may save lives

Posted: 09 Nov 2015 06:20 AM PST

Ambulances deployed at temporary locations that can be changed depending on the time of day and accident statistics can reduce response time and may save lives on the way to the hospital.

Movies as a tool to assess acceptability of intimate partner violence

Posted: 09 Nov 2015 05:49 AM PST

A new study uses passages from movies to analyze the acceptability of violence against women in couple relationships. Intimate partner violence against women by their male partners is a widespread phenomenon across countries and cultures, although in varying degrees. It is the most common form of violence suffered by women, with an estimated global prevalence of around 30%, decreasing to 23.2% in high-income regions, and a global percentage of female homicides committed by their intimate partners of 38.6%, rising to 41.2% in western countries, suggest the authors.

World first blood test reduces risk, increases accuracy in prenatal testing

Posted: 09 Nov 2015 05:39 AM PST

Research into a simple, accurate and low risk blood test that can detect fetal blood group, sex, and genetic conditions in unborn babies, report scientists. The new, simple and safe DNA blood test could spell the end of invasive amniocentesis and chorionic villus sampling, they say.

FIGHT study demonstrates type-2 diabetes therapy ineffective in the treatment of high-risk heart failure patients

Posted: 09 Nov 2015 05:39 AM PST

In an attempt to correct defects in the energy generation that contributes to poor pump function among heart failure patients, researchers examined whether the diabetes drug liraglutide, could improve the condition of patients with advanced heart failure. Despite improvements in blood sugar control, the therapy did not improve the clinical stability or pumping action of the heart in patients with advanced heart failure.

Effectiveness of drug to improve natriuretic peptide levels for chronic heart failure

Posted: 09 Nov 2015 05:39 AM PST

Medical researchers randomly assigned 456 patients with worsening chronic HF and reduced left ventricular ejection fraction (a measure of how well the left ventricle of the heart pumps with each beat) to receive placebo or 1 of 4 daily target doses of the medication vericiguat for 12 weeks.

Research reveals main reasons why people go to work when ill

Posted: 09 Nov 2015 05:39 AM PST

High job demands, stress and job insecurity are among the main reasons why people go to work when they are ill, according to new British research. The study aims to improve understanding of the key causes of employees going to work when sick, known as presenteeism, and to help make managers more aware of the existence of the growing phenomenon, what triggers the behavior and what can be done to improve employees' health and productivity.

Diagnosing and treating diabetes in heart attack patients improves heart outcomes

Posted: 09 Nov 2015 05:39 AM PST

People with heart problems often have diabetes, which puts them at greater risk for heart attacks, heart failure and stroke. Now, a new study has found that ensuring heart attack patients are promptly diagnosed and treated for diabetes makes a significant difference in improving their cardiac outcomes.

Just one energy drink may boost heart disease risk in young adults

Posted: 09 Nov 2015 05:38 AM PST

Drinking one 16-ounce energy drink boosts blood pressure and stress hormone responses in young, healthy adults, according to a new study. These changes could conceivably trigger new cardiovascular events.

Negative body image, not depression, increases adolescent obesity risk

Posted: 09 Nov 2015 05:34 AM PST

Negative body image significantly increases the risk of obesity regardless of whether youth have depression, according to researchers. For the study's purposes, persons with a body mass index of 30 or more were considered obese.

Increased meat consumption, especially when cooked at high temperatures, linked to elevated kidney cancer risk

Posted: 09 Nov 2015 05:34 AM PST

Diets high in meat may lead to an increased risk of developing renal cell carcinoma (RCC) through intake of carcinogenic compounds created by certain cooking techniques, such as barbecuing and pan-frying.

Watching cement dry could help dental fillings last longer

Posted: 09 Nov 2015 05:34 AM PST

Scientists have revealed 'sweet points' for dental fillings, where cement used to fill cracks regain elasticity before hardening indefinitely. This could have implications for creating more durable and longer-lasting fillings in the future.

Self-weighing may be a hazardous behavior among young women

Posted: 09 Nov 2015 05:34 AM PST

Self-weighing can be a useful tool to help adults control their weight, but for adolescents and young adults this behavior may have negative psychological outcomes. Researchers tracked the self-weighing behaviors of more than 1,900 young adults and found increases in self-weighing to be significantly related to increases in weight concern and depression and decreases in body satisfaction and self-esteem among females.

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