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- Advanced colorectal cancer: Anti-interleukin-1 alpha antibody MABp1 improves outcomes significantly over placebo
- Trauma induces more alcohol craving than stress among veterans with PTSD and co-occurring alcohol dependence
- Dividing T cells: A potential target for improving cancer immunotherapy
- Fetal surgery stands to advance from new glues inspired by mussels
- Reasons for delays in early autism diagnoses in Australia
- New anti-cancer strategy mobilizes both innate and adaptive immune response
- Natural metabolite can suppress inflammation
- Unexpected finding links cell division, glucose, and insulin
- Women with BRCA1 gene mutation at higher risk of deadly uterine cancer
- Regorafenib shows significant survival gains in refractory liver cancer
- Review article compared over-the-counter nasal dilators
| Posted: 02 Jul 2016 11:44 AM PDT A novel anti-interleukin 1-alpha antibody has shown a significant impact on symptoms, and a high level of safety and tolerability in patients with advanced colorectal cancer, according to phase III data. |
| Posted: 01 Jul 2016 03:34 PM PDT Post-traumatic stress disorder (PTSD) and alcohol dependence (AD) are two of the most common and debilitating disorders diagnosed among American military veterans. AD and PTSD often occur together, and this co-occurrence has a worse prognosis than either disorder alone. Alcohol craving is related to relapse, but the relationship between PTSD symptoms, craving, and relapse is not well understood. This study is the first to explore the effects of trauma-induced and stress-induced imagery on alcohol craving, affect, and cardiovascular and cortisol responses in a laboratory setting. |
| Dividing T cells: A potential target for improving cancer immunotherapy Posted: 01 Jul 2016 11:23 AM PDT When an immune T cell divides into two daughter cells, the activity of an enzyme called mTORC1, which controls protein production, splits unevenly between the progeny, producing two cells with different properties. Such 'asymmetric division,' uncovered by researchers using lab-grown cells and specially bred mice, could offer new ways to enhance cancer immunotherapy and may have other implications for studying how stem cells differentiate. |
| Fetal surgery stands to advance from new glues inspired by mussels Posted: 01 Jul 2016 09:05 AM PDT Bioengineers are making better glues for medical procedures inside the body, a wet environment, applying what he and others before him have learned about underwater superglue-making techniques that have been developed and elaborated upon through eons of evolution by mussels, a brainless bivalve. |
| Reasons for delays in early autism diagnoses in Australia Posted: 01 Jul 2016 09:03 AM PDT A new study has found many Australian children with Autism Spectrum Disorder (ASD) may not be diagnosed until long after initial signs appear, prompting calls for improvements to the diagnostic process. |
| New anti-cancer strategy mobilizes both innate and adaptive immune response Posted: 01 Jul 2016 06:39 AM PDT Scientists have developed a new vaccine that involves injecting cells that have been modified so that they can stimulate both an innate immune response and the more specific adaptive response, which allows the body to keep memories and attack new tumor cells as they form. |
| Natural metabolite can suppress inflammation Posted: 30 Jun 2016 12:53 PM PDT An international research team has revealed a substance produced in humans that can suppress the pro-inflammatory activity of macrophages -- specific immune cells. The substance known as itaconate is released in large quantities by macrophages themselves and according to the scientists, acts as an antioxidant and anti-inflammatory agent. These properties make itaconate promising for the treatment of such pathologies as cardiac ischemia, metabolic disorders and autoimmune diseases which may be associated with excessive inflammation or oxidative stress. |
| Unexpected finding links cell division, glucose, and insulin Posted: 30 Jun 2016 11:50 AM PDT Proteins that play key roles in the timing of cell division also moonlight in regulating blood sugar levels, researchers have found. |
| Women with BRCA1 gene mutation at higher risk of deadly uterine cancer Posted: 30 Jun 2016 11:05 AM PDT Women who carry the BRCA1 gene mutation that dramatically increases their risk of breast and ovarian cancers are also at higher risk for a lethal form of uterine cancer, according to a new study. |
| Regorafenib shows significant survival gains in refractory liver cancer Posted: 30 Jun 2016 10:59 AM PDT Oral multikinase inhibitor regorafenib achieves significantly improved survival rates compared to placebo in patients with hepatocellular carcinoma, according to data from the phase III RESORCE trial. |
| Review article compared over-the-counter nasal dilators Posted: 30 Jun 2016 08:53 AM PDT The narrowest area of the nose is the internal nasal valve and obstruction can cause airflow trouble. A review article compares over-the-counter mechanical nasal dilators for their efficacy in dilating the internal nasal valve to improve nasal airflow. |
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