الخميس، 18 أغسطس 2016

ScienceDaily: Health & Medicine News

ScienceDaily: Health & Medicine News


The dangers of Pokémon Go similar to texting

Posted: 17 Aug 2016 10:23 AM PDT

It's taking over headlines around the world – people being injured playing Pokémon Go, a location-based augmented reality game. A new study says much of the danger in playing the game is similar to the hazards of texting, a subject he has studied in the past.

Post-transplant anxiety linked to complex instructions, caregiver empathy

Posted: 17 Aug 2016 10:21 AM PDT

Some anxiety is perfectly normal for kidney transplant patients, but new research suggests that medical staff can help patients feel more at ease when they leave the hospital and that could decrease the chances they'll be readmitted.

The gender divide in urology: Surgeon gender shapes the clinical landscape

Posted: 17 Aug 2016 10:21 AM PDT

Although female certified urologists are still a minority within the specialty, they perform many more procedures on women than their male colleagues, who perform more procedures on men than their female colleagues. As more women opt to specialize in urology, attention needs to be paid to the way gender shapes the clinical landscape, report researchers.

Music demonstrated to alleviate cancer patients' symptoms

Posted: 17 Aug 2016 10:19 AM PDT

A review looking at studies on the effect music interventions have on the treatment of cancer patients found treatment benefits for anxiety, pain, fatigue and overall quality of life.

Two percent testosterone solution improves sex drive and energy levels in men with hypogonadism

Posted: 17 Aug 2016 10:19 AM PDT

For men with hypogonadism, a condition in which the body does not produce enough testosterone, low sex drive and fatigue are common symptoms. For these men treatment with a 2 percent testosterone solution (T-sol) can be effective therapy. In a six-month open-label study of patients receiving T-sol, researchers noted improvement of low sex drive and low energy symptoms, and did not identify new safety concerns.

Study quantifies risk factors for preterm birth

Posted: 17 Aug 2016 10:17 AM PDT

A significant portion of preterm births might be avoided by reducing or eliminating three major risk factors: abnormalities in the interval between pregnancies, the mother's body mass index prior to pregnancy, and the amount of weight gain in pregnancy.

Roadblocks to research: bioethicist addresses lack of HIV studies in pregnant women

Posted: 17 Aug 2016 10:16 AM PDT

A new study is addressing the urgent need for effective HIV prevention and treatment for the estimated 1.5 million women worldwide with HIV who give birth each year.

How a protein could become the next big sweetener

Posted: 17 Aug 2016 10:16 AM PDT

High-fructose corn syrup and sugar are on the outs with calorie-wary consumers. As a result, low- and no-calorie alternatives have become popular, and soon, there could be another option that tastes more sugar-like than other substitutes. Scientists report a step toward commercial production of a fruit protein called brazzein that is far sweeter than sugar -- and has fewer calories.

Mouse study points way to shut down harmful immune response in lupus

Posted: 17 Aug 2016 07:20 AM PDT

Molecules that scavenge debris from dying cells appear to halt the cycle of chronic inflammation in lupus, while also enhancing the body's ability to combat flu, according to studies in mice.

Regenerative bandage heals diabetic wounds faster

Posted: 17 Aug 2016 07:17 AM PDT

An antioxidant bandage heals wounds four times faster by delivering a protein that promotes cell repair, report investigators. Called a "regenerative bandage," the novel material heals diabetic wounds four times faster than a standard bandage and has the added benefit of promoting healing without side effects.

Aggressive lung cancer's aggressiveness may be its Achilles' heel

Posted: 17 Aug 2016 07:15 AM PDT

Researchers have discovered a flaw in the armor of the most aggressive form of lung cancer, a weakness that doctors may be able to exploit to slow or even stop the disease. Remarkably, this vulnerability stems from the very aggressiveness that makes the cancer so deadly.

Low-income kids less likely to receive strabismus diagnoses

Posted: 17 Aug 2016 07:15 AM PDT

Back to school eye exams may not be the norm for all kids. A large study shows strabismus is diagnosed much less in poor communities which puts kids at risk for permanent vision loss.

A molecular alarm clock awakens resting ovules

Posted: 17 Aug 2016 06:15 AM PDT

At the start of reproductive life an ovary contains, on average, several thousands of immature ovules in a resting state that can last for several decades. But how does each resting ovule know that it is time to prepare for ovulation? In a new study, researchers discovered in the fruit fly a molecular "alarm clock" that tells resting ovules when is the right time to wake up. Defects in this alarm clock result in female fertility problems.

Real-time visualization of the function of bone-resorbing cells within animals

Posted: 17 Aug 2016 06:15 AM PDT

Researchers have discovered a way to visualize sites where bone-resorbing cells (osteoclasts) were in the process of resorbing bone in living mice. This real-time visualization of changes in osteoclast localization and activity allowed the successful measurement of bone resorption intensity. Since this enables simple and quick access to information on the activity of osteoclasts, this discovery will contribute to the early diagnosis of affected areas and the development of new therapeutic drugs.

Physical training and social support reduce frailty and malnutrition

Posted: 17 Aug 2016 06:12 AM PDT

A training program for the reactivation of older and frail people has achieved remarkable success. It was revealed that physical training and addressing nutrition-relevant aspects with the aid of non-professional volunteers at home has had positive effects on the physical condition. Particularly the "social aspect" is of great significance.

US and Mexican controls on precursor chemicals may reduce cocaine and meth use in the US

Posted: 17 Aug 2016 06:10 AM PDT

In December 2006, the USA regulated sodium permanganate, a chemical essential to the manufacture of cocaine. In March 2007, Mexico closed a chemical company accused of illicitly importing more than 60 tons of pseudoephedrine, a methamphetamine precursor chemical. A new study has found that those events were associated with large, extended reductions in cocaine and methamphetamine users in the USA.

New findings detail how beneficial bacteria in the nose suppress pathogenic bacteria

Posted: 17 Aug 2016 06:10 AM PDT

Staphylococcus aureus is a common colonizer of the human body. Although, one quarter of the US population live with the bacteria and never get sick, having S. aureus present in the nostrils is a risk for infections that range in severity from mild skin to life- threatening MRSA infections. Research is providing insight into how harmless Corynebacterium species, bacterial members of the nasal and skin microbiome, help protect humans from disease.

CRISPR-Cas9 breaks genes better if you disrupt DNA repair

Posted: 17 Aug 2016 06:06 AM PDT

The popular gene-editing tool CRISPR-Cas9 competes with DNA repair, continually cutting what repair enzymes fix until the enzymes make a mistake, resulting in a broken gene. This led to a trick to improve cutting efficiency of the Cas9 protein. By dumping random bits of non-homologous DNA into the cell with Cas9, they disrupted the DNA repair process and boosted knockout efficiency up to five fold in human cell lines.

TERRA, the RNAs that protect telomeres

Posted: 17 Aug 2016 06:06 AM PDT

Despite their especially compact structure that is difficult to access, telomeres transcribe information like the rest of the DNA. The RNAs resulting from this process are called TERRA and their function is essential in preserving these protective structures.

Average of two injuries every hour in the US from strollers, carriers

Posted: 17 Aug 2016 06:06 AM PDT

Over a 21-year period from 1990 through 2010, almost 361,000 children aged 5 years and younger were treated in US hospital emergency departments for stroller- or carrier-related injuries -- that's about two children every hour.

Researchers working to advance aging research

Posted: 17 Aug 2016 06:06 AM PDT

Researchers have published six manuscripts that map strategies for taking new drugs that target processes underlying aging into clinical trials. They believe that these agents hold promise for treating multiple age-related diseases and disabilities.

Bone marrow transplant patients report better quality of life compared to peripheral blood transplant recipients from unrelated volunteer donors

Posted: 16 Aug 2016 12:33 PM PDT

A large, nationwide study finds better psychological well-being, fewer graft vs. host disease symptoms and greater likelihood of returning to work among bone marrow transplant recipients.

Cellular snowplow keeps genes open

Posted: 16 Aug 2016 12:29 PM PDT

A new discovery has revealed how special genes stay open for business, helping diagram a mechanism that plays a key role in fighting inflammation and infections.

Study details sources of discrepancies between initial and final pathology reports

Posted: 16 Aug 2016 12:19 PM PDT

Scientists detail the hospital procedures that lead to discrepancies between initial, intraoperative pathology evaluation and the results of the final, less pressured examination.

Potential therapeutic target for Huntington's disease

Posted: 16 Aug 2016 12:19 PM PDT

There is new hope in the fight against Huntington's disease. Scientists have discovered that changing a specific part of the huntingtin protein prevented the loss of critical brain cells and protected against behavioral symptoms in a mouse model of the disease.

Study suggests ways to block hypertension in those with sleep apnea

Posted: 16 Aug 2016 12:18 PM PDT

Suppressing hydrogen sulfide production in the carotid body may block the hypertension associated with sleep apnea.

Chronic pain linked to partners of people with depression

Posted: 16 Aug 2016 12:18 PM PDT

Partners of people with depression are more likely to suffer from chronic pain, research has found. The study shows that the two conditions share common causes -- some of which are genetic whilst other causes originate from the environment that partners share.

Unhealthy habits cost Canadians six years of life

Posted: 16 Aug 2016 12:18 PM PDT

Unhealthy habits are costing Canadians an estimated six years of life, according to a study. Researchers found that smoking, poor diet, physical inactivity, and unhealthy alcohol consumption contribute to about 50 percent of deaths in Canada.

Data sharing should become routine for best reponse to public health emergencies

Posted: 16 Aug 2016 12:18 PM PDT

The recent outbreaks caused by Ebola and Zika viruses have highlighted the importance of medical and public health research in accelerating outbreak control and have prompted calls for researchers to share data rapidly and widely during public health emergencies. However, the routine practice of data sharing in scientific research, rather than reactive data sharing, will be needed to effectively prepare for future public health emergencies, according to researchers.

Genetic and environmental risk factors for chronic pain

Posted: 16 Aug 2016 12:18 PM PDT

Both genetic factors and family environment contribute to risk for chronic pain, and contributions of many genes contribute to risk of both chronic pain and major depressive disorder (MDD), according to a new study.

Harms reporting in trials of orlistat

Posted: 16 Aug 2016 12:18 PM PDT

The reporting of trials of orlistat in the 1990s appears to have understated harms, both in the summarized results and in published papers, warn experts.

Duration of adulthood overweight, obesity linked to cancer risk in US women

Posted: 16 Aug 2016 12:18 PM PDT

The duration of overweight and obesity in women's adult lives is associated with cancer risk, according to a longitudinal study.

Scientists find a salty way to kill MRSA

Posted: 16 Aug 2016 11:07 AM PDT

Scientists have discovered a new way to attack Staphylococcus aureus bacteria. The team has revealed how the bacteria regulates its salt levels.

Prenatal BPA exposure linked to anxiety and depression in boys

Posted: 16 Aug 2016 11:06 AM PDT

Boys exposed prenatally to a common chemical used in plastics may be more likely to develop symptoms of anxiety and depression at age 10-12. The new study examined early life exposure to the chemical Bisphenol A (BPA).

Gene variant explains differences in diabetes drug response

Posted: 16 Aug 2016 10:41 AM PDT

A large international study of metformin, the world's most commonly used type 2 diabetes drug, reveals genetic differences among patients that may explain why some respond much better to the drug than others.

Connection between Ebola survival and co-infection with malaria parasites explored in new study

Posted: 16 Aug 2016 09:07 AM PDT

People infected with Ebola virus were 20 percent more likely to survive if they were co-infected with malaria-causing Plasmodium parasites, according to data collected at an Ebola diagnostic laboratory in Liberia in 2014-15. Moreover, greater numbers of Plasmodium parasites correlated with increased rates of Ebola survival, according to the new study.

Healthy people more at ease socializing with stocky folks, but it can hinder weight loss

Posted: 16 Aug 2016 09:07 AM PDT

People trying to shed pounds -- but who hang out with heavier pals regularly -- are more likely to lose weight if they include thinner people in their social lives, according to a study.

Use of feeding tubes decreases among nursing home residents with advanced dementia

Posted: 16 Aug 2016 09:06 AM PDT

Researchers examined feeding tube insertion rates from 2000-2014 among US nursing home residents with advanced dementia.

Recently approved cholesterol medication not cost-effective

Posted: 16 Aug 2016 09:06 AM PDT

Although the recently FDA-approved cholesterol-lowering drugs, PCSK9 inhibitors, could substantially reduce heart attacks, strokes, and cardiovascular deaths, they would not be cost-effective for use in patients with heterozygous familial hypercholesterolemia or atherosclerotic cardiovascular disease, with annual drug prices needing to be reduced by more than two-thirds to meet a generally acceptable threshold for cost-effectiveness, according to a study.

Injected drug reduces risk of fracture among women with osteoporosis

Posted: 16 Aug 2016 09:06 AM PDT

Among postmenopausal women with osteoporosis at risk of fracture, daily injection of the drug abaloparatide for 18 months significantly reduced the risk of new vertebral and nonvertebral fractures compared with placebo, according to a study.

Studying blood flow dynamics to identify the heart of vessel failure

Posted: 16 Aug 2016 09:06 AM PDT

New research from a fluid mechanics team reveals how blood flow dynamics within blood vessels may influence where plaques develop or rupture. The findings could one day help doctors identify weak spots on a vessel wall that are likeliest to fail, and lead to early interventions in treating heart disease.

Probability data could better direct lymph node removal for thyroid cancer

Posted: 16 Aug 2016 08:15 AM PDT

Surgeons operating on patients with advanced thyroid cancer are often conflicted when deciding how many lymph nodes they should remove to reduce the patient's risk of recurrence.

New maths to predict dangerous hospital epidemics

Posted: 16 Aug 2016 08:12 AM PDT

Mathematicians are now developing completely new statistical calculations on the world's fastest computers in order to be able to predict how epidemics of dangerous hospital bacteria spread.

Steroid treatment in very low birth weight infants may contribute to vision problems

Posted: 16 Aug 2016 08:11 AM PDT

It has long been suspected that steroids may have negative neurodevelopmental effects on very premature infants. In a new study, researchers found that for very premature infants with birth weights of less than 500 grams, there was a 1.6 times increased risk for retinopathy of prematurity (ROP) and a 1.7 times greater chance for advanced ROP.

LGBT persons get limited educational info for assisted reproductive technology, study finds

Posted: 16 Aug 2016 08:10 AM PDT

With the recent one-year anniversary of Obergefell vs. Hodges -- the landmark US Supreme Court decision legalizing same-sex marriage -- researchers have published a report that identifies unequal online availability of educational materials regarding assisted reproductive technology.

New method simplifies blood biomarker discovery and analysis

Posted: 16 Aug 2016 08:10 AM PDT

A new gene expression analysis method has been developed to widen the usage of blood in biomarker discovery and analysis, report scientists in a new article.

Researchers identify key elements of cellular response to proteasome dysfunction

Posted: 16 Aug 2016 08:10 AM PDT

Investigators have identified key molecules in the pathway by which cells in the C. elegans roundworm sense proteasome dysfunction, findings that may have application to treatment of several human diseases.

New study reveals a novel protein linked to type 2 diabetes

Posted: 16 Aug 2016 08:10 AM PDT

A possible new explanation as to why most people who are obese develop insulin resistance and type 2 diabetes has been revealed by researchers. A minority of obese individuals, the so-called healthy obese, have normal insulin sensitivity and are not diabetic.

Researchers discover the hidden potential of disordered proteins

Posted: 16 Aug 2016 08:10 AM PDT

Scientists have rediscovered the utility of disordered regions of proteins as drug targets. These results pave the way towards identifying new therapeutic targets for many diseases, they say.

Molecule prevents effect of chemotherapy

Posted: 16 Aug 2016 08:07 AM PDT

For the last three years a research team has been working on the development of a so-called biomarker to predict treatment effectiveness in colorectal cancer. Now the researchers found a molecule which is closely associated with the effect of Oxaliplatin treatment, an anti-cancer drug widely used in the treatment of this cancer.

Researchers identify the secret genetic weapon of Clostridium difficile

Posted: 16 Aug 2016 08:07 AM PDT

A trio of researchers has identified the location of the genes that control production of toxins that harm people infected by Clostridium difficile bacteria. The gene locus, agr1, forms part of a signaling communication system that produces a small molecule that, in turn, tells the rest of the population to turn on their toxin genes.

New enzyme-mapping advance could help drug development

Posted: 16 Aug 2016 06:22 AM PDT

Scientists have identified the structure of an enzyme that could be a good target for drugs combating three diseases common in the developing world.

Plaque psoriasis patients find many treatments, but few satisfied with their current plan

Posted: 16 Aug 2016 06:22 AM PDT

A new national survey in the United States of nearly 600 individuals with psoriasis, reveals that although patients have numerous treatment options, they have difficulty finding treatment plans that work. In addition, respondents reported a heavy emotional toll, with many feeling isolated and stigmatized due to the condition.

It's true: Latinos age slower than other ethnicities

Posted: 16 Aug 2016 05:51 AM PDT

Latinos age at a slower rate than other ethnic groups, a new study confirms. The findings may one day help scientists understand how to slow the aging process for everyone.

Microscale and macroscale brain disruptions are associated in schizophrenia

Posted: 16 Aug 2016 05:50 AM PDT

Brain abnormalities in schizophrenia have been identified at the microscale (alterations in synaptic connections between neurons) and the macroscale (altered connections between brain regions). Findings of these two levels of abnormalities have emerged separately, but a new study reports that the microscale and macroscale changes may go hand in hand.

New MRI technique sheds technology's longtime limits

Posted: 16 Aug 2016 05:47 AM PDT

Since its emergence in the 1970s, magnetic resonance imaging (MRI) has given physicians a better look inside tissues, helping to diagnose maladies from brain tumors to internal bleeding to torn ligaments. A new technology creates images resolved enough to enable consistent diagnoses across populations for the first time.

Diet and exercise can reduce protein build-ups linked to Alzheimer's, study shows

Posted: 16 Aug 2016 05:47 AM PDT

A healthy diet, regular physical activity and a normal body mass index can reduce the incidence of protein build-ups that are associated with the onset of Alzheimer's disease, research shows.

New guidance for administering hemorrhage prevention treatment

Posted: 15 Aug 2016 07:01 PM PDT

Tranexamic acid (TXA) is currently being administered to injured patients by many prehospital air and ground systems, despite a lack of evidence supporting or refuting its efficacy in preventing hemorrhage. Several studies examining prehospital use of TXA are currently in progress, but until now there have been no guidelines for healthcare professionals administering TXA to patients. A new guidance document provides best practices for TXA administration by Emergency Medical Services (EMS) based on the best evidence currently available.

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