ScienceDaily: Health & Medicine News

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• Naciam: N-acetylcysteine offers a post-MI boost
• Nebivolol prevents anthracycline-induced cardiotoxicity
• Up to 80 percent of heart failure patients denied therapy to reduce hospitalization and early death
• Heart failure in the elderly set to triple by 2060
• First epigenetic test to diagnose tumors of unknown origin
• New oral anticoagulants provide same stroke prevention as warfarin but cause less bleeding
• Direct catheter-based thrombectomy equal to bridging thrombolysis in ischemic stroke
• Alcohol-related hospitalization associated with doubled stroke risk in atrial fibrillation
• Smartphone detects atrial fibrillation with existing hardware
• Low socioeconomic status associated with higher risk of second heart attack or stroke
• Moderate physical activity linked with 50 percent reduction in cardiovascular death in over-65s
• Activity tracker uses heart rate to personalize amount of exercise needed to prevent early death
• Impulsivity levels help identify at-risk offspring of alcoholics
• Scientists uncover common cell signaling pathway awry in some types of autism
• Sertraline, brand named Zoloft, improves functioning in young children with fragile X
• MicroRNAs as Potential Link Between Obesity and Heart Disease
• Could the paleo diet benefit heart health?
• Probing how CRISPR-Cas9 works
• Study provides voice for evacuation needs of mobility impaired
• Bacteria in smokeless tobacco products may be a health concern

Naciam: N-acetylcysteine offers a post-MI boost Posted: 28 Aug 2016 06:01 AM PDT The addition of intravenous (IV) N-acetylcysteine (NAC) to IV glyceryl trinitrate (GTN) significantly reduced infarct size by approximately one third in patients undergoing percutaneous coronary intervention (PCI) after ST-segment elevation acute myocardial infarction (STEMI), according to Hot Line research reported here.

Nebivolol prevents anthracycline-induced cardiotoxicity Posted: 28 Aug 2016 05:58 AM PDT Nebivolol prevents anthracycline-induced cardiotoxicity, according to new research.

Up to 80 percent of heart failure patients denied therapy to reduce hospitalization and early death Posted: 28 Aug 2016 05:58 AM PDT A study in nearly 15,000 heart failure patients has found that up to 80 percent may not be receiving treatment at doses proven to reduce hospitalizations and improve survival. The research highlights the need for doctors to ensure patients are treated appropriately so that the high levels of serious illnesses and death associated with heart failure can be reduced.

Heart failure in the elderly set to triple by 2060 Posted: 28 Aug 2016 05:58 AM PDT Heart failure in the elderly is set to triple by 2060, according to new data.

First epigenetic test to diagnose tumors of unknown origin Posted: 27 Aug 2016 12:59 PM PDT It is possible to use a newly-developed epigenetic test called EPICUP® to find out what type of primary tumor is responsible for the metastasis in the patient in cancer of unknown primary cases, which will allow doctors to develop more specific treatments against it.

New oral anticoagulants provide same stroke prevention as warfarin but cause less bleeding Posted: 27 Aug 2016 12:58 PM PDT The new oral anticoagulants provide the same stroke prevention as warfarin but cause less intracranial bleeding, reports an observational study in more than 43,000 patients.

Direct catheter-based thrombectomy equal to bridging thrombolysis in ischemic stroke Posted: 27 Aug 2016 12:58 PM PDT Direct catheter-based thrombectomy is equally effective to bridging thrombolysis in the treatment of acute ischemic stroke, according to new results.

Alcohol-related hospitalization associated with doubled stroke risk in atrial fibrillation Posted: 27 Aug 2016 12:58 PM PDT Alcohol-related hospitalization is associated with a doubled risk of ischemic stroke risk in patients with non-valvular atrial fibrillation, according to a new study. The observational study was conducted in more than 25,000 non-valvular atrial fibrillation patients at low risk of stroke.

Smartphone detects atrial fibrillation with existing hardware Posted: 27 Aug 2016 12:58 PM PDT Smartphones can be used to detect atrial fibrillation with existing hardware, according to new research. A low-cost application has been developed that uses the phone's own accelerometer and gyroscope to check for atrial fibrillation.

Low socioeconomic status associated with higher risk of second heart attack or stroke Posted: 27 Aug 2016 12:58 PM PDT Low socioeconomic status is associated with a higher risk of a second heart attack or stroke, according to new research. The study in nearly 30,000 patients with a prior heart attack found that the risk of a second event was 36 percent lower for those in the highest income quintile compared to the lowest and increased by 14 percent in divorced compared to married patients.

Moderate physical activity linked with 50 percent reduction in cardiovascular death in over-65s Posted: 27 Aug 2016 12:58 PM PDT Moderate physical activity is associated with a greater than 50 percent reduction in cardiovascular death in over-65s, according to research. The 12-year study in nearly 2,500 adults aged 65 to 74 years found that moderate physical activity reduced the risk of an acute cardiovascular event by more than 30 percent. High levels of physical activity led to greater risk reductions.

Activity tracker uses heart rate to personalize amount of exercise needed to prevent early death Posted: 27 Aug 2016 12:58 PM PDT A novel activity tracker has been developed that uses heart rate data to personalize the amount of exercise needed to reduce the risk of death from cardiovascular disease.

Impulsivity levels help identify at-risk offspring of alcoholics Posted: 26 Aug 2016 03:34 PM PDT Researchers know that youth with a family history of alcoholism have a greater risk of developing an alcohol use disorder; this heightened vulnerability may be due to impulsive behavior. For this study, researchers examined "waiting" impulsivity – a tendency toward prematurely responding to a reward, and previously associated with a predisposition to drinking. The study sample comprised young, moderate-to-heavy social drinkers who were either positive (FHP) or negative (FHN) for a family history of alcoholism. Impulsivity was assessed after an alcoholic or non-alcoholic drink.

Scientists uncover common cell signaling pathway awry in some types of autism Posted: 26 Aug 2016 12:17 PM PDT Skin cells derived from autistic donors grew faster than those from control subjects, and activated their genes in distinct patterns, scientists report. Genes related to cell growth were unusually active, leading to more cells but fewer connections between them. This can cause faulty cell networks unable to properly transmit signals in the brain and enlarged heads during early development, say the researchers.

Sertraline, brand named Zoloft, improves functioning in young children with fragile X Posted: 26 Aug 2016 12:17 PM PDT Treatment with sertraline may provide nominal but important improvements in cognition and social participation in very young children with fragile X syndrome, the most common genetic cause of intellectual disability and the leading single-gene cause of autism, a study has found.

MicroRNAs as Potential Link Between Obesity and Heart Disease Posted: 26 Aug 2016 12:17 PM PDT Results from a new study suggest that small molecules known as microRNAs may be part of the pathway connecting inflammation with increased heart disease risk in obese people.

Could the paleo diet benefit heart health? Posted: 26 Aug 2016 12:17 PM PDT Findings from a small study suggest that people who followed the Paleo diet for only eight weeks experienced positive effects on heart health.

Probing how CRISPR-Cas9 works Posted: 26 Aug 2016 12:15 PM PDT A new study reveals important new details about the inner workings of the CRISPR-Cas9 machinery in live cells that may have implications for the development of therapeutics that use the powerful gene editing tool.

Study provides voice for evacuation needs of mobility impaired Posted: 26 Aug 2016 11:20 AM PDT A new study details the challenges faced by people with mobility impairments during emergency evacuation from multistory buildings. The findings are especially relevant because they are based upon concerns, insights and opinions provided in interviews with members of a population with egress needs that often go unheard when evacuation procedures are designed, implemented and practiced.

Bacteria in smokeless tobacco products may be a health concern Posted: 26 Aug 2016 11:20 AM PDT Several species of bacteria found in smokeless tobacco products have been associated with opportunistic infections, according to a new paper. An estimated 8 million people use smokeless tobacco products in the US. But there has been little data on the microbial populations that exist within these products.

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