ScienceDaily: Health & Medicine News

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• Likely causes and treatment strategies for systemic scleroderma identified
• Gene and stem cell therapy combination could aid wound healing
• Novel way discovered to 'switch on' tumor suppressors that have been silenced
• Barriers to implementing complimentary medicine into MD residency
• Running a marathon hard on heart, especially in less prepared runners
• Readmission rates impacted by patients' knowledge, skills
• Scientists use blur to sharpen DNA mapping
• New research shows that blood pressure remains a problem in China
• High dietary intake of polyphenols are associated with longevity
• Visits to multiple HIV clinics linked to poorer outcomes
• Does good cholesterol increase breast cancer risk?
• Multivitamins with minerals may protect older women with invasive breast cancer
• Cellular signals between pancreatic cancer tumors, saliva
• 'Mobility shoes' take a load off for knee osteoarthritis sufferers
• Aircraft noise linked to heart disease, study suggests
• Scientists discover new mechanism that preserves genomic integrity and is abnormal in the rare DiGeorge syndrome
• Better community engagement and stronger health systems are needed to tackle polio
• Expanding flu vaccination policies to include children could reduce infections and mortality
• Explaining why infections in newborns link to later behavior problems
• New urine test could diagnose eye disease
• Screening tool for detecting intimate partner violence among women veterans
• Blood vessel cells can repair, regenerate organs
• Growing bacteria keep time, know their place
• Study finds biomarker differentiating the inattentive, combined subtypes of ADHD
• Where does dizziness come from?
• HIV vaccines elicit immune response in infants
• Use of hypothermia may be harmful for severe meningitis

Likely causes and treatment strategies for systemic scleroderma identified Posted: 09 Oct 2013 11:15 AM PDT Using mice, lab-grown cells and clues from a related disorder, researchers have greatly increased understanding of the causes of systemic sclerosis, showing that a critical culprit is a defect in the way certain cells communicate with their structural scaffolding. They say the new insights point the way toward potentially developing drugs for the disease, which affects approximately 100,000 people in the United States.

Gene and stem cell therapy combination could aid wound healing Posted: 09 Oct 2013 10:22 AM PDT Researchers, working with elderly mice, have determined that combining gene therapy with an extra boost of the same stem cells the body already uses to repair itself leads to faster healing of burns and greater blood flow to the site of the wound.

Novel way discovered to 'switch on' tumor suppressors that have been silenced Posted: 09 Oct 2013 10:22 AM PDT Scientists have found that a novel noncoding ribonucleic acid (RNA) offers the potential for "switching on" of tumor suppressors that have been shut off.

Barriers to implementing complimentary medicine into MD residency Posted: 09 Oct 2013 10:01 AM PDT Investigators have identified that lack of time and a paucity of trained faculty are perceived as the most significant barriers to incorporating complementary and alternative medicine and integrative medicine training into family medicine residency curricula and training programs.

Running a marathon hard on heart, especially in less prepared runners Posted: 09 Oct 2013 10:01 AM PDT Investigators who studied a group of recreational marathon runners have established that strenuous exercise, such as running a marathon, can damage the heart muscle. Although they found the effect is temporary and reversible, they warn that these effects are more widespread in less fit distance runners and that recreational distance runners should prepare properly before marathons.

Readmission rates impacted by patients' knowledge, skills Posted: 09 Oct 2013 10:01 AM PDT A study by physicians has found that patients with a high degree of activation (possessing the knowledge, skills, confidence and inclination to assume responsibility for managing one's health and health-care needs) were less likely to be readmitted to the hospital within 30 days of discharge than those with a low level of activation.

Scientists use blur to sharpen DNA mapping Posted: 09 Oct 2013 08:11 AM PDT Researchers have found a simple way to pinpoint the location of specific sequences along single strands of DNA, a technique that could someday help diagnose genetic diseases.

New research shows that blood pressure remains a problem in China Posted: 09 Oct 2013 08:10 AM PDT With a recent World Health Organization report showing hypertension affects over 40% of Chinese adults aged 45 or older, combating high blood pressure will be high on the agenda of the 24th Great Wall International Congress of Cardiology & Asia Pacific Heart Congress.

High dietary intake of polyphenols are associated with longevity Posted: 09 Oct 2013 08:10 AM PDT A scientific study has, for the first time, associated high polyphenols intake with a 30% reduction in mortality in older adults. The research evaluated the total dietary polyphenol intake by using a nutritional biomarker.

Visits to multiple HIV clinics linked to poorer outcomes Posted: 09 Oct 2013 07:57 AM PDT Patients who received care at multiple HIV clinics — as opposed to only one — were less likely to take their medication and had higher HIV viral loads, a new study found. The findings reinforce the notion that continuous care with one provider/clinic is optimal for outcomes and even reducing transmissions, and can help cut down on duplicative HIV services that contribute to higher health care costs.

Does good cholesterol increase breast cancer risk? Posted: 09 Oct 2013 07:57 AM PDT A team of researchers has shown that an HDL receptor found on breast cancer cells may be responsible for making this cancer more aggressive, proposing a new molecular target that could help treat the disease.

Multivitamins with minerals may protect older women with invasive breast cancer Posted: 09 Oct 2013 07:57 AM PDT Findings from a study involving thousands of postmenopausal women suggest that women who develop invasive breast cancer may benefit from taking supplements containing both multivitamins and minerals. The new research found that the risk of dying from invasive breast cancer was 30 percent lower among multivitamin/mineral users compared with nonusers.

Cellular signals between pancreatic cancer tumors, saliva Posted: 09 Oct 2013 07:06 AM PDT Pancreatic cancer is one of the deadliest forms of cancer. Most of those with the disease will die within the first year of diagnosis, and just 6 percent will survive five years. The disease is typically diagnosed through an invasive and complicated biopsy. But a discovery by researchers may be one major step toward creating a noninvasive tool that would enable clinicians and oncologists to detect pancreatic cancer through a simple risk assessment test using saliva.

'Mobility shoes' take a load off for knee osteoarthritis sufferers Posted: 09 Oct 2013 07:06 AM PDT The results of a new study by bone and joint experts suggest that patients with knee osteoarthritis who wear flat, flexible footwear, which allows natural foot mobility and provides sufficient support for the foot, had significant reduction in knee loading -- the force placed upon the joint during daily activities.

Aircraft noise linked to heart disease, study suggests Posted: 09 Oct 2013 07:06 AM PDT Exposure to high levels of aircraft noise is associated with an increased risk of cardiovascular disease, find two studies published on bmj.com today.

Scientists discover new mechanism that preserves genomic integrity and is abnormal in the rare DiGeorge syndrome Posted: 09 Oct 2013 07:00 AM PDT Scientists have described a molecular mechanism that facilitates the defense of the human genome against "bombarding" by mobile DNA sequences. Abnormalities in the mechanism could be responsible for some symptoms of DiGeorge syndrome, a rare disease. The research could in the future help develop new therapies against the disease, which is caused by the microdeletion of a small part of chromosome 22.

Better community engagement and stronger health systems are needed to tackle polio Posted: 08 Oct 2013 03:23 PM PDT Two independently written articles call for a shift away from the leader-centric approach that polio eradication campaigns are currently pursuing in the three countries (Nigeria, Pakistan and Afghanistan) where the disease remains endemic.

Expanding flu vaccination policies to include children could reduce infections and mortality Posted: 08 Oct 2013 03:23 PM PDT The current influenza (flu) vaccination policy in England and Wales should be expanded to target 5 to 16-year-olds in order to further reduce the number of deaths from flu, according to a new study.

Explaining why infections in newborns link to later behavior problems Posted: 08 Oct 2013 03:21 PM PDT Researchers exploring the link between newborn infections and later behavior and movement problems have found that inflammation in the brain keeps cells from accessing iron that they need to perform a critical role in brain development.

New urine test could diagnose eye disease Posted: 08 Oct 2013 12:22 PM PDT You might not think to look to a urine test to diagnose an eye disease. But a new study says it can link what is in a patient's urine to gene mutations that cause retinitis pigmentosa, an inherited, degenerative disease that results in severe vision impairment and often blindness.

Screening tool for detecting intimate partner violence among women veterans Posted: 08 Oct 2013 12:22 PM PDT Researchers have identified a promising screening tool to detect intimate partner violence in females in the VA Boston Healthcare System. The findings accurately detected 78 percent of women identified as abused within the past year by a more comprehensive and behaviorally specific scale.

Blood vessel cells can repair, regenerate organs Posted: 08 Oct 2013 12:22 PM PDT Damaged or diseased organs may someday be healed with an injection of blood vessel cells, eliminating the need for donated organs and transplants.

Growing bacteria keep time, know their place Posted: 08 Oct 2013 12:22 PM PDT Working with a synthetic gene circuit designed to coax bacteria to grow in a predictable ring pattern, scientists have revealed an under-appreciated contributor to natural pattern formation: Time.

Study finds biomarker differentiating the inattentive, combined subtypes of ADHD Posted: 08 Oct 2013 12:22 PM PDT Using a common test of brain functioning, researchers have found differences in the brains of adolescents with the inattentive and combined subtypes of attention-deficit/hyperactivity disorder and teens who do not have the condition, suggesting that the test may offer a potential biomarker for differentiating the types of the disorder.

Where does dizziness come from? Posted: 08 Oct 2013 12:20 PM PDT Researchers say they have pinpointed a site in a highly developed area of the human brain that plays an important role in the subconscious recognition of which way is straight up and which way is down.

HIV vaccines elicit immune response in infants Posted: 08 Oct 2013 11:21 AM PDT A new analysis of two HIV vaccine trials that involved pediatric patients shows that the investigational vaccines stimulated a critical immune response in infants born to HIV-infected mothers.

Use of hypothermia may be harmful for severe meningitis Posted: 08 Oct 2013 09:24 AM PDT Treatment using hypothermia is sometimes used to improve the functional outcome of comatose patients with bacterial meningitis. However, new research is suggesting that this technique may be more harmful than the use of standard care.

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