الثلاثاء، 3 يوليو 2012

ScienceDaily: Health & Medicine News

ScienceDaily: Health & Medicine News


Charting autism's neural circuitry: Deleting single gene results in autism-like behavior and immunosuppressant drug prevents symptoms

Posted: 02 Jul 2012 06:03 PM PDT

Deleting a single gene in the cerebellum of mice can cause key autistic-like symptoms, researchers have found. They also discovered that rapamycin, a commonly used immunosuppressant drug, prevented these symptoms.

Kids with behavior problems, disabilities bullied more, more likely to bully others

Posted: 02 Jul 2012 06:02 PM PDT

Students receiving special-education services for behavioral disorders and those with more obvious disabilities are more likely to be bullied than their general-education counterparts -- and are also more likely to bully other students, a new study shows.

Autism, schizophrenia and bipolar disorder may share common underlying factors, family histories suggest

Posted: 02 Jul 2012 06:02 PM PDT

New research points to an increased risk of autism spectrum disorders among individuals whose parents or siblings have been diagnosed with schizophrenia or bipolar disorder.

Fast food intake increases risk of diabetes and heart disease in Singapore

Posted: 02 Jul 2012 06:02 PM PDT

Researchers have examined the eating habits of residents in Singapore and found new evidence that a diet heavy in fast food increases the risk of developing Type 2 diabetes and coronary heart disease.

Women infected with common parasite have increased risk of attempting suicide, study finds

Posted: 02 Jul 2012 06:01 PM PDT

Women infected with the Toxoplasma gondii parasite, which is spread through contact with cat feces or eating undercooked meat or unwashed vegetables, are at increased risk of attempting suicide, according to a new study of more than 45,000 women.

Teen sexting prevalent: Nearly 30 percent send nude pictures despite being 'bothered' by requests

Posted: 02 Jul 2012 06:00 PM PDT

A study of students at seven public high schools in Texas suggests that "sexting" was prevalent and may be linked to teens' sexual behaviors.

Uncontrollable anger prevalent among U.S. youth: Almost two-thirds have history of anger attacks

Posted: 02 Jul 2012 06:00 PM PDT

Nearly two-thirds of U.S. adolescents have experienced an anger attack in their lives that involved threatening violence or violent behavior. These severe attacks of uncontrollable anger are much more common among adolescents than previously recognized. Nearly one in 12 adolescents -- close to six million young people -- meet criteria for a diagnosis of Intermittent Explosive Disorder (IED), a syndrome characterized by persistent uncontrollable anger attacks not accounted for by other mental disorders.

Botulinum toxin a shot in the arm for preventing multiple sclerosis tremor

Posted: 02 Jul 2012 06:00 PM PDT

Botulinum toxin may help prevent shaking or tremor in the arms and hands of people with multiple sclerosis (MS), according to new research.

Success reported in treating autism spectrum disorder in mice

Posted: 02 Jul 2012 04:25 PM PDT

Using a mouse model of autism, researchers have successfully treated an autism spectrum disorder characterized by severe cognitive impairment.

New brain receptor for drug 'fantasy' identified

Posted: 02 Jul 2012 04:25 PM PDT

Researchers are closer to understanding the biology behind GHB (gamma-hydroxybutyric acid), a transmitter substance in the brain, best known in its synthetic form as the illegal drug fantasy.

Breaking the skin barrier: Drugs topically deliver gene therapy via commercial moisturizers for skin disease treatment

Posted: 02 Jul 2012 04:25 PM PDT

"Getting under your skin" takes on new meaning thanks to research that could transform gene therapy. A team from the fields of dermatology and nanotechnology is the first to demonstrate the use of commercial moisturizers to deliver gene therapy with great potential for life-saving therapies for skin cancers. The drug -- consisting of novel spherical arrangements of nucleic acids -- penetrates the skin's layers and can selectively target disease-causing genes while sparing normal genes.

Day dreaming good for you? Reflection is critical for development and well-being

Posted: 02 Jul 2012 03:40 PM PDT

As each day passes, the pace of life seems to accelerate -- demands on productivity continue ever upward and there is hardly ever a moment when we aren't, in some way, in touch with our family, friends, or coworkers. While moments for reflection may be hard to come by, a new article suggests that the long-lost art of introspection --even daydreaming -- may be an increasingly valuable part of life.

New way to grow, isolate cancer cells may add weapon against disease

Posted: 02 Jul 2012 03:40 PM PDT

A new method to isolate and grow the most dangerous cancer cells could enable new research into how cancer spreads and, ultimately, how to fight it. Researchers found that while a traditional culture of cancer cells has only a few capable of starting new tumors, a soft gel is capable of isolating tumor-repopulating cells and promoting the growth and multiplication of these cells in culture. The new culture technique could allow researchers to better study metastatic cancers.

Activity of rare genetic variant in glioma validated

Posted: 02 Jul 2012 03:39 PM PDT

Researchers have validated a link between a rare genetic variant and the risk of glioma, the most common and lethal type of brain tumor. The validation study also uncovered an association between the same rare genetic variant and improved rates of survival for patients with glioma.

Higher energies for laser-accelerated particles possible

Posted: 02 Jul 2012 02:28 PM PDT

Physicists have demonstrated for the first time that laser-accelerated protons follow the direction of the laser light. By incorporating this new data into a conventional model describing the laser particle acceleration, high proton energies which have not been realized so far might become achievable. This is important for developing laser particle acceleration for cancer therapy.

Rare leukemia-causing protein discovered

Posted: 02 Jul 2012 02:28 PM PDT

Researchers have discovered a new gene target for leukemia therapy. Researchers found that by inhibiting in animal models the protein Vav3, which controls cell signaling, the development of this leukemia -- known as BCR-ABL lymphoid leukemia -- is delayed.

Why heart attacks cause so much more damage in late pregnancy

Posted: 02 Jul 2012 01:24 PM PDT

While research has shown that the heart typically functions better during pregnancy due to a rise in cardiac pumping capacity to meet increased demands, a new study in rats and mice demonstrates that heart attacks occurring in the last trimester or late months of pregnancy result in worse heart function and more damaged heart tissue than heart attacks among non-pregnant females. This early study may help identify and better understand the mechanisms involved in the higher risks of heart disease during pregnancy.

Naked mole rat may hold the secret to long life

Posted: 02 Jul 2012 01:23 PM PDT

The naked mole rat's brain contains unusually high levels of NRG-1, a neuroprotecting protein, which preserves high activity, bone health, and cognitive ability throughout its lifespan, new research shows. And because the rodent has an 85 percent genetic similarity to humans, continuing investigation could lead to a longer and healthier life for us.

Researchers block pathway to cancer cell replication

Posted: 02 Jul 2012 01:23 PM PDT

Research suggests that patients with leukemia sometimes relapse because standard chemotherapy fails to kill the self-renewing leukemia initiating cells, often referred to as cancer stem cells. In such cancers, the cells lie dormant for a time, only to later begin cloning, resulting in a return and metastasis of the disease. One such type of cancer is called pediatric T cell acute lymphoblastic leukemia, often found in children, who have few treatment options beyond chemotherapy.

In vitro study identifies potential combination therapy for breast cancer

Posted: 02 Jul 2012 01:23 PM PDT

A new study demonstrates an effective combination therapy for breast cancer cells in vitro. The findings raise the possibility of using this type of combination therapy for different forms of breast cancer, including those that develop resistance to chemotherapy and other treatments.

Hormone discovered that preserves insulin production and beta cell function in diabetes

Posted: 02 Jul 2012 01:23 PM PDT

Researchers have found protective, anti-diabetic functions for a hormone that, like insulin, is produced by the islet cells of the pancreas. The new hormone was found to stimulate insulin secretion from rat and human islet cells and protect islet cells in the presence of toxic, cell-killing factors used in the study.

Surprising culprit behind chemo resistance in rare cancer

Posted: 02 Jul 2012 01:21 PM PDT

Researchers have shown how an aggressive form of multiple myeloma resists chemotherapy. Multiple myeloma is a rare cancer of plasma cells in the bone marrow. Though the finding has no immediate benefit for patients, the scientists say it could help guide research into better treatments.

Physical activity needed to reap benefits of dietary restriction

Posted: 02 Jul 2012 01:21 PM PDT

Dietary restriction alone does not extend lifespan – at least in fruit flies. Flies, which share many genetic similarities with humans, need physical activity in order to live longer on a Spartan diet. If the same axiom holds true in humans, those practicing caloric restriction in hopes of living longer need to make sure they eat enough to avoid fatigue.

Mosquitoes: How we smell is why they bite

Posted: 02 Jul 2012 12:32 PM PDT

A mosquito biologist is studying the olfactory behavior of mosquitoes as a means of developing more effective methods of disease control.

'Self-distancing' can help people calm aggressive reactions, study finds

Posted: 02 Jul 2012 12:32 PM PDT

A new study reveals a simple strategy that people can use to minimize how angry and aggressive they get when they are provoked by others.

Electronic medical record improves physician compliance of reviewing portal images, study suggests

Posted: 02 Jul 2012 12:32 PM PDT

The use of an electronic medical record for reviewing portal images dramatically improves compliance with timeliness and record keeping, according to a new study. Portal images are used to verify the positioning of patients during daily radiation treatments to improve the accuracy of the radiation field placement, to reduce exposure to normal tissue and to deliver accurate dose to tumor volumes.

Innate immune system protein provides a new target in war against bacterial infections

Posted: 02 Jul 2012 12:32 PM PDT

Scientists have identified a possible new approach to defeating bacterial infections by targeting an innate immune system component in a bid to invigorate the immune response.

Years before diagnosis, quality of life declines for Parkinson's disease patients

Posted: 02 Jul 2012 12:32 PM PDT

Growing evidence suggests that Parkinson's disease often starts with non-motor symptoms that precede diagnosis by several years. In the first study to examine patterns in the quality of life of Parkinson' disease patients prior to diagnosis, researchers have documented declines in physical and mental health, pain, and emotional health beginning several years before the onset of the disease and continuing thereafter.

Cutaneous human papillomavirus infection a risk factor for skin cancer

Posted: 02 Jul 2012 12:31 PM PDT

Researchers conducted a case control study and found associations between having antibodies to certain types of cutaneous human papillomavirus and a kind of skin cancer called squamous cell carcinoma. According to the researchers, evidence has been emerging that cutaneous human papillomavirus infection (not the mucosal HPV infection that is associated with cervical cancers) may be an additional risk factor for SCC.

Measuring the uncertainties of pandemic influenza

Posted: 02 Jul 2012 12:31 PM PDT

A major collaboration between US research centers has highlighted three factors that could ultimately determine whether an outbreak of influenza becomes a serious epidemic that threatens national health. The research suggests that the numbers in current response plans could be out by a factor of two or more depending on the characteristics of the particular pandemic influenza.

Natural intestinal flora strengthen immune system

Posted: 02 Jul 2012 12:29 PM PDT

Signals from natural intestinal bacteria are necessary for an effective immune response to various viral or bacterial germs, new research suggests.

You can't keep a good cell down: Vast majority of cells close to death after toxin exposure can survive and thrive

Posted: 02 Jul 2012 12:26 PM PDT

The vast majority of cells that appear to be on a one-way track to death after exposure to toxins can bounce back completely after those toxins are removed, scientists report in a new study. The finding is not only a testament to the indomitable cellular spirit, but could also offer some practical insight on how to save dying tissues after heart attacks or strokes as well as prevent cancer in cells transiently exposed to toxins.

Brain researchers start mapping the human 'connectome'

Posted: 02 Jul 2012 12:26 PM PDT

A research effort called the Human Connectome Project is seeking to explore, define, and map the functional connections of the human brain.

Premature infants do feel pain from procedures: Physiological markers for neonate pain identified

Posted: 02 Jul 2012 12:26 PM PDT

There was a time when a belief was widely held that premature neonates did not perceive pain. That, of course, has been refuted but measurements of neonate pain tend to rely on inexact measures, such as alertness and ability to react expressively to pain sensations. Researchers reported that there is a significant relationship between procedural pain and detectable oxidative stress in neonates.

Got kids? Then you're less likely to catch a cold

Posted: 02 Jul 2012 12:26 PM PDT

Being a parent reduces your risk of catching a cold—possibly because of unknown "psychological or behavioral differences between parents and nonparents," according to a new study.

Chronic inflammation in the brain leads the way to Alzheimer's disease

Posted: 02 Jul 2012 10:48 AM PDT

A new article suggests that chronic inflammation can predispose the brain to develop Alzheimer's disease.

World's number of IVF and ICSI babies has now reached a calculated total of 5 million

Posted: 02 Jul 2012 10:47 AM PDT

The number of babies born as a result of assisted reproduction technologies (ART) has reached an estimated total of 5 million since the world's first, Louise Brown, was born in July 1978.

Diving seabirds: Working hard and living long

Posted: 02 Jul 2012 10:47 AM PDT

Scientists have found that diving birds reach their 30s and then die quickly and suddenly, showing few signs of aging prior to death. Their findings could help us understand the aging process, providing critical insights for our aging population.

Abuse during childhood may contribute to obesity in adulthood

Posted: 02 Jul 2012 10:47 AM PDT

Investigators report research findings that may shed light on influences on obesity during adulthood. The study found an association of severity of sexual and physical abuse during childhood and adolescence with obesity during adulthood.

Seasonal changes in outpatient antibiotic use significantly alter seasonal patterns of drug resistance

Posted: 02 Jul 2012 10:47 AM PDT

A new study shows how seasonal changes in outpatient antibiotic use -- retail sales of antibiotics typically get a boost during the winter -- can significantly alter seasonal patterns of drug resistance. The findings suggest that hospital campaigns to reduce inappropriate antibiotic use should be coordinated with efforts in the broader community if they are to be most effective.

Why cancer rate increases with age (it's not what you think)

Posted: 02 Jul 2012 10:47 AM PDT

A new review presents compelling evidence against conventional wisdom's opinion that the accumulation of oncogenic mutations drives higher cancer rates in the elderly.

Viewing media coverage of terrorist attacks causes an increase in chronic pain intensity

Posted: 02 Jul 2012 10:44 AM PDT

Scientists have shown that exposure to terrorist attacks through the media predicted an increase in pain intensity and in the sensory component of pain during the pre-post war period, but did not predict depression or anxiety.

Childless women with fertility problems at higher risk of hospitalization for psychiatric disorders

Posted: 02 Jul 2012 10:44 AM PDT

Based on the largest cohort of women with fertility problems compiled to date, Danish investigators have shown that women who remained childless after their first investigation for infertility had more hospitalizations for psychiatric disorders than women who had at least one child following their investigation.

Single protein promotes resistance to widely used anti-estrogen drugs

Posted: 02 Jul 2012 10:44 AM PDT

Researchers have uncovered a single molecule they say is a major determinant of resistance to anti-estrogen therapy used to treat or prevent breast cancer in high-risk women. The scientists say glucose-regulated protein 78, activated as breast cells undergo stress induced by the agents tamoxifen and fulvestrant, turns off apoptosis, a cell death response, and turns on autophagy.

Physics confirms sprinters are performing better than ever before

Posted: 02 Jul 2012 10:40 AM PDT

Experts reveal that the men's 100 m sprint will be one event not to miss this summer.

Achieve Olympic feet with barefoot running

Posted: 02 Jul 2012 10:32 AM PDT

British Olympic runners could run more economically by just taking off their shoes, say researchers.

Drinking coffee may reduce risk of most common form of skin cancer

Posted: 02 Jul 2012 10:29 AM PDT

Increasing the number of cups of caffeinated coffee you drink could lower your risk of developing the most common form of skin cancer, basal cell carcinoma, according to a new article.

Invest in public health now for healthier future, experts urge

Posted: 02 Jul 2012 10:29 AM PDT

A special July/August issue of the Journal of Public Health Management and Practice (JPHMP), dedicated to public health financing, suggests that a rebalancing of the US healthcare investment in clinical care and public health initiatives is needed to improve the health of the population and reduce overall costs.

3-D movies linked to increased vision symptoms

Posted: 02 Jul 2012 10:29 AM PDT

Watching 3-D movies can "immerse" you in the experience -— but can also lead to visual symptoms and even motion sickness, reports a new article.

Novel mechanism and potential link responsible for Huntington's disease

Posted: 02 Jul 2012 10:29 AM PDT

Using an in vitro cell model of Huntington's disease (HD), researchers have discovered a novel mechanism and potential link between mutant huntingtin, cell loss and cell death or apoptosis in the brain, which is responsible for the devastating effects of this disease.

Potential treatment target identified in an animal model of pancreatic cancer

Posted: 01 Jul 2012 04:16 PM PDT

Detailed analysis of genes expressed in circulating tumor cells -- cells that break off from solid tumors and travel through the bloodstream -- has identified a potential treatment target in metastatic pancreatic cancer.

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